ID   A0A172RW46_9ACTN        Unreviewed;       475 AA.
AC   A0A172RW46;
DT   07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT   07-SEP-2016, sequence version 1.
DT   03-MAY-2023, entry version 28.
DE   RecName: Full=M18 family aminopeptidase {ECO:0000256|RuleBase:RU004387};
DE            EC=3.4.11.- {ECO:0000256|RuleBase:RU004387};
GN   ORFNames=SAMN02910314_00343 {ECO:0000313|EMBL:SEO46315.1};
OS   Denitrobacterium detoxificans.
OC   Bacteria; Actinomycetota; Coriobacteriia; Eggerthellales; Eggerthellaceae;
OC   Denitrobacterium.
OX   NCBI_TaxID=79604 {ECO:0000313|EMBL:SEO46315.1, ECO:0000313|Proteomes:UP000182975};
RN   [1] {ECO:0000313|Proteomes:UP000182975}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 21843 {ECO:0000313|Proteomes:UP000182975};
RA   Varghese N.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- COFACTOR:
CC       Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC         Evidence={ECO:0000256|ARBA:ARBA00001947,
CC         ECO:0000256|RuleBase:RU004387};
CC   -!- SIMILARITY: Belongs to the peptidase M18 family.
CC       {ECO:0000256|ARBA:ARBA00008290, ECO:0000256|RuleBase:RU004386}.
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DR   EMBL; FOEC01000001; SEO46315.1; -; Genomic_DNA.
DR   RefSeq; WP_066660154.1; NZ_FOEC01000001.1.
DR   AlphaFoldDB; A0A172RW46; -.
DR   STRING; 79604.AAY81_00740; -.
DR   KEGG; ddt:AAY81_00740; -.
DR   PATRIC; fig|79604.3.peg.151; -.
DR   OrthoDB; 5288740at2; -.
DR   Proteomes; UP000182975; Unassembled WGS sequence.
DR   GO; GO:0004177; F:aminopeptidase activity; IEA:UniProtKB-KW.
DR   GO; GO:0008237; F:metallopeptidase activity; IEA:UniProtKB-KW.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR   Gene3D; 2.30.250.10; Aminopeptidase i, Domain 2; 1.
DR   Gene3D; 3.40.630.10; Zn peptidases; 1.
DR   InterPro; IPR001948; Peptidase_M18.
DR   InterPro; IPR023358; Peptidase_M18_dom2.
DR   PANTHER; PTHR28570; ASPARTYL AMINOPEPTIDASE; 1.
DR   PANTHER; PTHR28570:SF2; M18 FAMILY AMINOPEPTIDASE 1-RELATED; 1.
DR   Pfam; PF02127; Peptidase_M18; 1.
DR   PRINTS; PR00932; AMINO1PTASE.
DR   SUPFAM; SSF101821; Aminopeptidase/glucanase lid domain; 1.
DR   SUPFAM; SSF53187; Zn-dependent exopeptidases; 1.
PE   3: Inferred from homology;
KW   Aminopeptidase {ECO:0000256|ARBA:ARBA00022438,
KW   ECO:0000256|RuleBase:RU004386};
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|RuleBase:RU004386};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723,
KW   ECO:0000256|RuleBase:RU004386};
KW   Metalloprotease {ECO:0000256|ARBA:ARBA00023049,
KW   ECO:0000256|RuleBase:RU004386};
KW   Protease {ECO:0000256|ARBA:ARBA00022670, ECO:0000256|RuleBase:RU004386};
KW   Reference proteome {ECO:0000313|Proteomes:UP000182975};
KW   Zinc {ECO:0000256|ARBA:ARBA00022833, ECO:0000256|RuleBase:RU004386}.
SQ   SEQUENCE   475 AA;  51148 MW;  AA0C1B25E9C9F9B4 CRC64;
     MERKNAWKAY SEEDLVKVTN LANSYIDFIS SCKTERECAA YVMETARAAG YRSLEEVRAA
     GQALKPGDRV YASNYDKSVM LVQIGKKPLE EGFNILGAHI DSPRLDVKQN PLYEQNDFAL
     LDTHYYGGVK KYQWVTVPLA IHGVVVKKDG AKVQVNVGED AADPAFCVTD LLIHLGADQL
     KKDGGHVVEG EDLDVLVGGR PLVVSEEDAK AAPKGSAEAM AAKEPVKAAI VKLFREKYGF
     DEEDLLSAEL EVVPAGRARS CGFDESMVLG YGQDDRVCSY PSLIAQLQAG DLDRTAICLL
     VDKEEIGSVG ATGMTSMFFE NTVAEIMALA GEEGDLPLRR ALAASNMLSS DVSAGIDPLY
     ANAFDVKNAG MLGHGLVFNK YTGARGKSGS NDANAEYMGK IRGIMDAGNV TFHTCELGKV
     DQGGGGTIAY ILAKYGMNVI DCGVPVLSMH APWEVTNKAD IYEALKGYSA FLQYA
//