ID A0A172RZ03_9ACTN Unreviewed; 557 AA.
AC A0A172RZ03;
DT 07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT 07-SEP-2016, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE SubName: Full=Acetyl-CoA synthetase {ECO:0000313|EMBL:SEO73874.1};
GN ORFNames=SAMN02910314_01034 {ECO:0000313|EMBL:SEO73874.1};
OS Denitrobacterium detoxificans.
OC Bacteria; Actinomycetota; Coriobacteriia; Eggerthellales; Eggerthellaceae;
OC Denitrobacterium.
OX NCBI_TaxID=79604 {ECO:0000313|EMBL:SEO73874.1, ECO:0000313|Proteomes:UP000182975};
RN [1] {ECO:0000313|Proteomes:UP000182975}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 21843 {ECO:0000313|Proteomes:UP000182975};
RA Varghese N.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the ATP-dependent AMP-binding enzyme family.
CC {ECO:0000256|ARBA:ARBA00006432}.
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DR EMBL; FOEC01000005; SEO73874.1; -; Genomic_DNA.
DR RefSeq; WP_066663317.1; NZ_FOEC01000005.1.
DR AlphaFoldDB; A0A172RZ03; -.
DR STRING; 79604.AAY81_07340; -.
DR KEGG; ddt:AAY81_07340; -.
DR PATRIC; fig|79604.3.peg.1479; -.
DR OrthoDB; 9803968at2; -.
DR Proteomes; UP000182975; Unassembled WGS sequence.
DR GO; GO:0016878; F:acid-thiol ligase activity; IEA:UniProt.
DR GO; GO:0016405; F:CoA-ligase activity; IEA:UniProt.
DR Gene3D; 3.30.300.30; -; 1.
DR Gene3D; 3.40.50.12780; N-terminal domain of ligase-like; 1.
DR InterPro; IPR025110; AMP-bd_C.
DR InterPro; IPR045851; AMP-bd_C_sf.
DR InterPro; IPR020845; AMP-binding_CS.
DR InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR InterPro; IPR042099; ANL_N_sf.
DR PANTHER; PTHR43605:SF10; ACYL-COA SYNTHETASE MEDIUM CHAIN FAMILY MEMBER 3; 1.
DR PANTHER; PTHR43605; ACYL-COENZYME A SYNTHETASE; 1.
DR Pfam; PF00501; AMP-binding; 1.
DR Pfam; PF13193; AMP-binding_C; 1.
DR SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 1.
DR PROSITE; PS00455; AMP_BINDING; 1.
PE 3: Inferred from homology;
KW Ligase {ECO:0000256|ARBA:ARBA00022598};
KW Reference proteome {ECO:0000313|Proteomes:UP000182975}.
FT DOMAIN 40..400
FT /note="AMP-dependent synthetase/ligase"
FT /evidence="ECO:0000259|Pfam:PF00501"
FT DOMAIN 465..543
FT /note="AMP-binding enzyme C-terminal"
FT /evidence="ECO:0000259|Pfam:PF13193"
SQ SEQUENCE 557 AA; 62849 MW; 18610E0439782AFD CRC64;
MDYILSKYCP RIEFDSYEDF FENFTINIPQ NFNFAYDVVD EWARVEPEKK ALVWVDDNDD
RKEFTFSDIS RMSNQMANVF WEQGIRKGDV VLMILRRRWE YWVCAMALCK IGATVVPATI
QLTRKDIAYR CNLAGVKMMV CVNDDYVCEQ TELALQDAPS VQGKIVCGGE REGWLSFSDL
IASASPEWQR PEGDAATQID DIMLMYFTSG TTGNAKAVEH SFKHPFGHII TAKYWQQVQE
NKLHMSVTDS GWAKFGWGKL YGQWMAGACV FCYDMMKFVP AKLLQVMQDY KLTTFCAPPT
MYRFMLQEDV ASYDLSPIQN FATAGEPLNA EVTVAWERLT GKKIREGFGQ SEGPVLVATF
PWLEPRPGSM GKPSPLLNIR LLDDDGNFVP DGEEGAICVT HLKDAYPPGL FVGYFGDPER
TKEALGGEYY NLHDMAWRDP DGYLSFVGRN DDVIKCSGYR IGPFEVESAL VAHPAVVECA
VTAAPDPIRG KVVKATVVLA RGYEGTPELT KELQNHVKKT TAPYKYPRIV EYVDELPKTV
GGKIKRKLIR TNDGIAD
//
