ID A0A172USJ0_9MYCO Unreviewed; 622 AA.
AC A0A172USJ0;
DT 07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT 07-SEP-2016, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE SubName: Full=Propionyl-CoA synthetase {ECO:0000313|EMBL:ANE81910.1};
GN Name=prpE {ECO:0000313|EMBL:ANE81910.1};
GN ORFNames=A7U43_23935 {ECO:0000313|EMBL:ANE81910.1};
OS Mycobacterium adipatum.
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Mycobacteriaceae;
OC Mycobacterium.
OX NCBI_TaxID=1682113 {ECO:0000313|EMBL:ANE81910.1, ECO:0000313|Proteomes:UP000077143};
RN [1] {ECO:0000313|EMBL:ANE81910.1, ECO:0000313|Proteomes:UP000077143}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=YC-RL4 {ECO:0000313|EMBL:ANE81910.1,
RC ECO:0000313|Proteomes:UP000077143};
RA Ren L., Fan S., Ruth N., Jia Y., Wang J., Qiao C.;
RT "Complete genome sequence of a phthalic acid esters degrading Mycobacterium
RT sp. YC-RL4.";
RL Submitted (MAY-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the ATP-dependent AMP-binding enzyme family.
CC {ECO:0000256|ARBA:ARBA00006432}.
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DR EMBL; CP015596; ANE81910.1; -; Genomic_DNA.
DR RefSeq; WP_068000000.1; NZ_CP015596.1.
DR AlphaFoldDB; A0A172USJ0; -.
DR STRING; 1682113.A7U43_23935; -.
DR KEGG; madi:A7U43_23935; -.
DR OrthoDB; 9803968at2; -.
DR Proteomes; UP000077143; Chromosome.
DR CDD; cd05967; PrpE; 1.
DR Gene3D; 3.30.300.30; -; 1.
DR Gene3D; 3.40.50.12780; N-terminal domain of ligase-like; 1.
DR InterPro; IPR032387; ACAS_N.
DR InterPro; IPR025110; AMP-bd_C.
DR InterPro; IPR045851; AMP-bd_C_sf.
DR InterPro; IPR020845; AMP-binding_CS.
DR InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR InterPro; IPR042099; ANL_N_sf.
DR PANTHER; PTHR43347; ACYL-COA SYNTHETASE; 1.
DR PANTHER; PTHR43347:SF3; ACYL-COA SYNTHETASE SHORT-CHAIN FAMILY MEMBER 3, MITOCHONDRIAL; 1.
DR Pfam; PF16177; ACAS_N; 1.
DR Pfam; PF00501; AMP-binding; 1.
DR Pfam; PF13193; AMP-binding_C; 1.
DR SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 1.
DR PROSITE; PS00455; AMP_BINDING; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000077143}.
FT DOMAIN 4..58
FT /note="Acetyl-coenzyme A synthetase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF16177"
FT DOMAIN 60..445
FT /note="AMP-dependent synthetase/ligase"
FT /evidence="ECO:0000259|Pfam:PF00501"
FT DOMAIN 510..586
FT /note="AMP-binding enzyme C-terminal"
FT /evidence="ECO:0000259|Pfam:PF13193"
SQ SEQUENCE 622 AA; 66857 MW; 8FCDF1FF64DDFFBF CRC64;
MSGYRALFDA SITDPSTFWA DAAKGVTWTR EPQRVLDDSN PPFYRWFPDG ELNTCANALD
RHIAERGDQA ALIYDSPVTG TKRVYTYREL LDQTARFAGV LQGLGVAKGD RVVIYMPMVP
EAVIAMLACA RLGAVHSVVF GGFAGHELAT RIDDARPTVV VSASCGIEPT RTVEYKPMLD
AALRLAEHTT PKCVILQREQ HPCELVEGRD VDWAQAMAAV QPVDPVPVAA TDPLYVLYTS
GTTGKPKGIV RDNGGHAVAL LWTMRHLYDI EPGDVFWAAS DVGWVVGHSY IVYAPLLLGA
TTVLYEGKPV GTPDAGAFWR VAAEHKVKAL FTAPTAIRAI KKEDPDAKLL ADYDLSGLKY
LFQAGERLDP GTYEWASEKL GIPVIDHWWQ TETGWAIAAD PMGVEALPVK PGSATVPMPG
YDVRVLRLDG SECEPGEEGS ICIKLPLPPG TLPTLWGDGA RYVSSYLSAF DGYYLTGDGG
HIDADGYLFV VGRTDDVINV AGHRMSTGSI EAVLAGHPAV AECAVIGVAD ELKGQVPRGL
VVLKSGASAD GVADELIDAV RNDIGAVASF KLVDVVAALP KTRSGKILRK TMRGIADGRD
EPVPSTIEDP SVLEALKETL QR
//
