ID A0A172YC19_9GAMM Unreviewed; 444 AA.
AC A0A172YC19;
DT 07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT 07-SEP-2016, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE RecName: Full=histidine kinase {ECO:0000256|ARBA:ARBA00012438};
DE EC=2.7.13.3 {ECO:0000256|ARBA:ARBA00012438};
GN ORFNames=A5892_04260 {ECO:0000313|EMBL:ANF56777.1};
OS Halotalea alkalilenta.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Oceanospirillales;
OC Halomonadaceae; Halotalea.
OX NCBI_TaxID=376489 {ECO:0000313|EMBL:ANF56777.1, ECO:0000313|Proteomes:UP000077875};
RN [1] {ECO:0000313|EMBL:ANF56777.1, ECO:0000313|Proteomes:UP000077875}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=IHB B 13600 {ECO:0000313|EMBL:ANF56777.1,
RC ECO:0000313|Proteomes:UP000077875};
RA Swarnkar M.K., Sharma A., Kaushal K., Soni R., Rana S., Singh A.K.,
RA Gulati A.;
RT "Complete Genome Sequence of Halotalea alkalilenta IHB B 13600.";
RL Submitted (APR-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + protein L-histidine = ADP + protein N-phospho-L-
CC histidine.; EC=2.7.13.3; Evidence={ECO:0000256|ARBA:ARBA00000085};
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DR EMBL; CP015243; ANF56777.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A172YC19; -.
DR STRING; 376489.A5892_04260; -.
DR KEGG; haa:A5892_04260; -.
DR Proteomes; UP000077875; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR CDD; cd06225; HAMP; 1.
DR CDD; cd00082; HisKA; 1.
DR Gene3D; 1.10.287.130; -; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR InterPro; IPR003660; HAMP_dom.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR005467; His_kinase_dom.
DR InterPro; IPR003661; HisK_dim/P.
DR InterPro; IPR036097; HisK_dim/P_sf.
DR InterPro; IPR004358; Sig_transdc_His_kin-like_C.
DR PANTHER; PTHR45436:SF15; SENSOR HISTIDINE KINASE CRDS; 1.
DR PANTHER; PTHR45436; SENSOR HISTIDINE KINASE YKOH; 1.
DR Pfam; PF00672; HAMP; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF00512; HisKA; 1.
DR PRINTS; PR00344; BCTRLSENSOR.
DR SMART; SM00304; HAMP; 1.
DR SMART; SM00387; HATPase_c; 1.
DR SMART; SM00388; HisKA; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF158472; HAMP domain-like; 1.
DR SUPFAM; SSF47384; Homodimeric domain of signal transducing histidine kinase; 1.
DR PROSITE; PS50885; HAMP; 1.
DR PROSITE; PS50109; HIS_KIN; 1.
PE 4: Predicted;
KW Kinase {ECO:0000256|ARBA:ARBA00022777}; Membrane {ECO:0000256|SAM:Phobius};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000077875};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius};
KW Two-component regulatory system {ECO:0000256|ARBA:ARBA00023012}.
FT TRANSMEM 156..179
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 180..233
FT /note="HAMP"
FT /evidence="ECO:0000259|PROSITE:PS50885"
FT DOMAIN 241..441
FT /note="Histidine kinase"
FT /evidence="ECO:0000259|PROSITE:PS50109"
SQ SEQUENCE 444 AA; 49538 MW; 5D1864033F6E7739 CRC64;
MITCTVALII TVTVVSLAVV TLLESNPTSF LGRHRQNDMG TRLIDTLRFD SQGNPQSVTL
IDEIHIWRAA FPDQFQYRVL DPQGTVLLSS EHLISNFPSA DDYFDPQAER FAVESDGRGF
HVETLPFTYD GNQFFLQTAV SDYLSEVIVR NRLKPVFTTV TIIAGISLGV FILAIYFTFH
SMFRPLRRVS DAAARISPEN LTSRLSLDGI PSEVRPLAEA FNSALDRLEE GFRVQQSFFA
SAAHELKTPL TLIRGQIELQ GDSSQQARLL QDVDLMSRHV QQLLHIAEVS ELYNYRSAST
DVVAVVDEVI RYLGRRAEKK RVRIVVAHRA TASALEADKA ALFILLKNLV ENAVEVSPES
AVVTIDISNH SVAVNDQGEG IDPAHLPHIF SKFWRAPGNK YEGAGLGLAI CWKIANTYGW
QLFVDRSVPH TRFVVLFDGQ VGNR
//
