ID A0A172ZF41_9BACL Unreviewed; 589 AA.
AC A0A172ZF41;
DT 07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT 07-SEP-2016, sequence version 1.
DT 27-MAR-2024, entry version 32.
DE SubName: Full=B12-binding domain-containing radical SAM protein {ECO:0000313|EMBL:ANF96113.1};
GN ORFNames=AR543_08945 {ECO:0000313|EMBL:ANF96113.1};
OS Paenibacillus bovis.
OC Bacteria; Bacillota; Bacilli; Bacillales; Paenibacillaceae; Paenibacillus.
OX NCBI_TaxID=1616788 {ECO:0000313|EMBL:ANF96113.1, ECO:0000313|Proteomes:UP000078148};
RN [1] {ECO:0000313|Proteomes:UP000078148}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BD3526 {ECO:0000313|Proteomes:UP000078148};
RA Wu Z., Gao C., Liu Z., Zheng H.;
RT "Genome of Paenibacillus bovis sp. nov.";
RL Submitted (OCT-2015) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:ANF96113.1, ECO:0000313|Proteomes:UP000078148}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BD3526 {ECO:0000313|EMBL:ANF96113.1,
RC ECO:0000313|Proteomes:UP000078148};
RX PubMed=26769366; DOI=10.1099/ijsem.0.000900;
RA Gao C., Han J., Liu Z., Xu X., Hang F., Wu Z.;
RT "Paenibacillus bovis sp. nov., isolated from raw yak (Bos grunniens)
RT milk.";
RL Int. J. Syst. Evol. Microbiol. 66:1413-1418(2016).
CC -!- COFACTOR:
CC Name=[4Fe-4S] cluster; Xref=ChEBI:CHEBI:49883;
CC Evidence={ECO:0000256|ARBA:ARBA00001966};
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DR EMBL; CP013023; ANF96113.1; -; Genomic_DNA.
DR RefSeq; WP_060533686.1; NZ_CP013023.1.
DR AlphaFoldDB; A0A172ZF41; -.
DR STRING; 1616788.AR543_08945; -.
DR KEGG; pbv:AR543_08945; -.
DR OrthoDB; 9801424at2; -.
DR Proteomes; UP000078148; Chromosome.
DR GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR GO; GO:0031419; F:cobalamin binding; IEA:InterPro.
DR GO; GO:0051536; F:iron-sulfur cluster binding; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR CDD; cd02068; radical_SAM_B12_BD; 1.
DR Gene3D; 3.40.50.280; Cobalamin-binding domain; 1.
DR Gene3D; 3.80.30.20; tm_1862 like domain; 1.
DR InterPro; IPR006158; Cobalamin-bd.
DR InterPro; IPR036724; Cobalamin-bd_sf.
DR InterPro; IPR025288; DUF4080.
DR InterPro; IPR006638; Elp3/MiaA/NifB-like_rSAM.
DR InterPro; IPR034466; Methyltransferase_Class_B.
DR InterPro; IPR007197; rSAM.
DR InterPro; IPR023404; rSAM_horseshoe.
DR PANTHER; PTHR43409; ANAEROBIC MAGNESIUM-PROTOPORPHYRIN IX MONOMETHYL ESTER CYCLASE-RELATED; 1.
DR PANTHER; PTHR43409:SF18; RADICAL SAM SUPERFAMILY PROTEIN; 1.
DR Pfam; PF02310; B12-binding; 1.
DR Pfam; PF13311; DUF4080; 1.
DR Pfam; PF04055; Radical_SAM; 1.
DR SFLD; SFLDG01082; B12-binding_domain_containing; 1.
DR SFLD; SFLDG01123; methyltransferase_(Class_B); 1.
DR SMART; SM00729; Elp3; 1.
DR SUPFAM; SSF52242; Cobalamin (vitamin B12)-binding domain; 1.
DR SUPFAM; SSF102114; Radical SAM enzymes; 1.
DR PROSITE; PS51332; B12_BINDING; 1.
DR PROSITE; PS51918; RADICAL_SAM; 1.
PE 4: Predicted;
KW 4Fe-4S {ECO:0000256|ARBA:ARBA00022485};
KW Iron {ECO:0000256|ARBA:ARBA00022485};
KW Iron-sulfur {ECO:0000256|ARBA:ARBA00022485};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000078148}.
FT DOMAIN 1..133
FT /note="B12-binding"
FT /evidence="ECO:0000259|PROSITE:PS51332"
FT DOMAIN 172..406
FT /note="Radical SAM core"
FT /evidence="ECO:0000259|PROSITE:PS51918"
SQ SEQUENCE 589 AA; 68952 MW; 078FD72E4ECCC5E0 CRC64;
MKVVLSTLNA KYIHTSLAIR CLKAYSEKDF DIELAEYTIK DPVMNIVSDL YQRRPDVIGF
SCYIWNIEET IKVIDVLRKV LPEVKIILGG PEVSYDTEHW MNRLTNVDFI VVGEGEETFH
HLLQEIEGAG KYHFIYGVAY RKGEEVIVMP GRPKQDLNEL PSPHRFAEDV ADLGKRVVYF
ETSRGCPFSC QFCLSSIEVG VRYFDIERTK SDILYLIENG AKLIKFVDRT FNIKRDYALE
MFRFLIENHN GCTFQFEITA DIMRPEVLDY LAEHAPPGVF RFEIGVQSTN DPTNELVKRR
QNFTKLSRTV TKIRESGKID QHLDLIAGLP MEDYNTFRKT FNDVFALGPE ELQLGFLKML
RGTGLRIDAD KYEYTYMDQA PYEILSSHML SFDDIVRLKR LEDVLEKYWN AHRMDYTLHY
LMKDEFSSPF DFFQEFGNYW EAQGWQKIGH QLEDLFIRLQ SFLRDRGTER MDVILGLMKL
DYFLNHKYKP RKIWWEPTVD KSRLNQHIQR AVRQPETISA EFAELDLDDK DMHKHMVMEE
LPFRLDQLLA GVPITGAQGR SLLMVAYQQN EQQKPLFFVA ALTSERAAL
//
