ID A0A176J6L5_9BACI Unreviewed; 494 AA.
AC A0A176J6L5;
DT 07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT 07-SEP-2016, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE RecName: Full=4,4'-diaponeurosporene oxygenase {ECO:0000256|ARBA:ARBA00039159};
DE AltName: Full=4,4'-diaponeurosporene oxidase {ECO:0000256|ARBA:ARBA00041900};
DE AltName: Full=Carotenoid oxidase {ECO:0000256|ARBA:ARBA00042619};
GN ORFNames=AS29_010440 {ECO:0000313|EMBL:KZZ84581.1};
OS Bacillus sp. SJS.
OC Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Bacillus.
OX NCBI_TaxID=1423321 {ECO:0000313|EMBL:KZZ84581.1, ECO:0000313|Proteomes:UP000028527};
RN [1] {ECO:0000313|EMBL:KZZ84581.1, ECO:0000313|Proteomes:UP000028527}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SJS {ECO:0000313|EMBL:KZZ84581.1,
RC ECO:0000313|Proteomes:UP000028527};
RA Newman J.D., Stropko S.J., Pipes S.E.;
RT "Bacillus sp. SJS genome.";
RL Submitted (APR-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=2 AH2 + all-trans-4,4'-diaponeurosporene + 2 O2 = 4,4'-
CC diaponeurosporenal + 2 A + 3 H2O; Xref=Rhea:RHEA:56104,
CC ChEBI:CHEBI:13193, ChEBI:CHEBI:15377, ChEBI:CHEBI:15379,
CC ChEBI:CHEBI:17499, ChEBI:CHEBI:62743, ChEBI:CHEBI:79065;
CC Evidence={ECO:0000256|ARBA:ARBA00035945};
CC -!- PATHWAY: Carotenoid biosynthesis; staphyloxanthin biosynthesis;
CC staphyloxanthin from farnesyl diphosphate: step 3/5.
CC {ECO:0000256|ARBA:ARBA00037901}.
CC -!- SIMILARITY: Belongs to the carotenoid/retinoid oxidoreductase family.
CC CrtP subfamily. {ECO:0000256|ARBA:ARBA00038194}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KZZ84581.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; JAQV02000018; KZZ84581.1; -; Genomic_DNA.
DR RefSeq; WP_035410644.1; NZ_JAQV02000018.1.
DR AlphaFoldDB; A0A176J6L5; -.
DR STRING; 1423321.AS29_010440; -.
DR eggNOG; COG1233; Bacteria.
DR OrthoDB; 9814556at2; -.
DR Proteomes; UP000028527; Unassembled WGS sequence.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR GO; GO:0016117; P:carotenoid biosynthetic process; IEA:UniProtKB-KW.
DR Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 2.
DR InterPro; IPR002937; Amino_oxidase.
DR InterPro; IPR014105; Carotenoid/retinoid_OxRdtase.
DR InterPro; IPR036188; FAD/NAD-bd_sf.
DR NCBIfam; TIGR02734; crtI_fam; 1.
DR PANTHER; PTHR43734:SF7; 4,4'-DIAPONEUROSPORENE OXYGENASE; 1.
DR PANTHER; PTHR43734; PHYTOENE DESATURASE; 1.
DR Pfam; PF01593; Amino_oxidase; 1.
DR SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
PE 3: Inferred from homology;
KW Carotenoid biosynthesis {ECO:0000256|ARBA:ARBA00022746,
KW ECO:0000256|RuleBase:RU362075};
KW Oxidoreductase {ECO:0000256|RuleBase:RU362075};
KW Reference proteome {ECO:0000313|Proteomes:UP000028527}.
FT DOMAIN 11..486
FT /note="Amine oxidase"
FT /evidence="ECO:0000259|Pfam:PF01593"
SQ SEQUENCE 494 AA; 55511 MW; C584BEDFE3195179 CRC64;
MKKAVVIGAG LGGLSAAITL ASEGWDVTVA EKNSHPGGKM MPVKLGSFHF DFGPNTITMP
QVFEEVFHKA GKKMQDYLKM VKLQKHTVNC FPDGTVFFLS SDKAAMKQQL RNLDPKGYRN
YDRFISEITR LYGLSEKHFF PRMFKSVLDY TSPSLSYAFM RVRPLETMDH FFRRYFGNEQ
VIQAFNRYAT YIGSSPYQSP ATFAMIAYLE LVQGVFYIKG GNTKIAEAFY ELAKEMGVQF
MMNTKVQELQ ISNKRINTVL LENGQELTAD EVILNADLLK SFPELVAESE RPHFTDKKRN
GYSPSISAFV ILAGIEGKID KLAHHSVFFS KNYRKEFDEL FKNQNYSEDP TIYISNSSFS
DPSQAAAGSN LFILVNAPPL NQDGRLQISP QDYKSLIYEK LEQAGVSLSG KIMEEQLFTP
LDIQDRFGAY RGALYGISAN KKWDAFMRPG NFPADIQNLS FAGGSTHPGG GSPMVTISGM
NVAEEIAKRE SKRR
//
