ID A0A176L412_9ACTN Unreviewed; 977 AA.
AC A0A176L412;
DT 07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT 07-SEP-2016, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:OAA99246.1};
GN ORFNames=A6P39_19355 {ECO:0000313|EMBL:OAA99246.1};
OS Streptomyces sp. FXJ1.172.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=710705 {ECO:0000313|EMBL:OAA99246.1};
RN [1] {ECO:0000313|EMBL:OAA99246.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=FXJ1.172 {ECO:0000313|EMBL:OAA99246.1};
RA Liu M., Liu N., Shang F., Huang Y.;
RT "Activation and identification of NC-1, a novel cryptic cyclodepsipeptide
RT from red soil-derived Streptomyces sp. FXJ1.172.";
RL Submitted (APR-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the AfsR/DnrI/RedD regulatory family.
CC {ECO:0000256|ARBA:ARBA00005820}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OAA99246.1}.
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DR EMBL; LWRP01000099; OAA99246.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A176L412; -.
DR STRING; 710705.A6P39_19355; -.
DR OrthoDB; 7628974at2; -.
DR GO; GO:0043531; F:ADP binding; IEA:InterPro.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0098542; P:defense response to other organism; IEA:UniProt.
DR GO; GO:0000160; P:phosphorelay signal transduction system; IEA:UniProtKB-KW.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd15831; BTAD; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 2.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR005158; BTAD.
DR InterPro; IPR002182; NB-ARC.
DR InterPro; IPR001867; OmpR/PhoB-type_DNA-bd.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR016032; Sig_transdc_resp-reg_C-effctor.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR InterPro; IPR019734; TPR_repeat.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR PANTHER; PTHR35807:SF1; TRANSCRIPTIONAL REGULATOR REDD; 1.
DR PANTHER; PTHR35807; TRANSCRIPTIONAL REGULATOR REDD-RELATED; 1.
DR Pfam; PF03704; BTAD; 1.
DR Pfam; PF00931; NB-ARC; 1.
DR Pfam; PF13424; TPR_12; 1.
DR PRINTS; PR00364; DISEASERSIST.
DR SMART; SM00382; AAA; 1.
DR SMART; SM01043; BTAD; 1.
DR SMART; SM00028; TPR; 6.
DR SMART; SM00862; Trans_reg_C; 1.
DR SUPFAM; SSF46894; C-terminal effector domain of the bipartite response regulators; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF48452; TPR-like; 3.
PE 3: Inferred from homology;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Two-component regulatory system {ECO:0000256|ARBA:ARBA00023012}.
FT DOMAIN 11..88
FT /note="OmpR/PhoB-type"
FT /evidence="ECO:0000259|SMART:SM00862"
FT DOMAIN 95..236
FT /note="Bacterial transcriptional activator"
FT /evidence="ECO:0000259|SMART:SM01043"
FT DOMAIN 307..459
FT /note="AAA+ ATPase"
FT /evidence="ECO:0000259|SMART:SM00382"
FT REGION 246..268
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 977 AA; 105579 MW; 03460BBC54514BD5 CRC64;
MLGPLHAQIT GREVRLDGPR QAKMLAALLV DANSVVAMER LVAVMWDGKA PATAVRQVQD
ALSGLRRNLA ACGASRSLIS TRRGGYQIHL TPDQLDLLEF DHERHLAEGH TNPFETAVAL
RRALACWRGN ALVDISSRVL ELDAARLDEK RAATHKLCLS IELDLGRHRE VIEELTALLR
EHPYDEQVAE HLMVALYRCR RQGEALQVYE RLRRTLAGEL GVDPTPPIQA LHRRILVADP
ALAAPAPASA PASGPSGTRP DSPGAAAGEP VMAMPVRQLP LDVPDFVGRA DALAEVARLL
DASAPDRAPV AVIVGGPGVG KSCLVTHAAR LASPTFPDGQ LYLNLAGTSD APRDPALMLA
EALRALSIAG SAIPNGLSER AALYRSLLAD RRMLVVLDDA GHADQVLPLL PGADGCAVLI
TSRTLLTQLP GARHIDLDVL SPAEARELFT GIVGRRRVER EPAEADAILD CCGNLPLAIR
IASAKLTGRP AWSLRVLRER IEDESRRLAE LRIGDLSVRA SVELSLRLLP ADAVRALSLL
GLLGAYTLPG WVVGPLLDRS DAEEVLDTLV DASLVRLTAT DAIGQPRYRL HDLIRTCAVE
TAAQLPAADK RGAIVRVLSA WLDLAGRGTD RLPAGLLAAP PGSAPRLSLP DAVVDRLLAD
PVGWFDVERD TLLGAVKLAV DWGLDELAWE LAASPVTYYD HRCLYQDWEH GHRLALDAAE
AAGNARGASV LLRGLGQLHI YRDEFDGATR ALASSVELCQ NGEDKRGEAL SMAMLGTVSR
VQGRYGEAAE RVEQALAVAS GEGDRHLEAQ LSCSMAVMRL MQGELDEAES WFGEALRQAR
ALDDGHRVAV VLRRFSRLHD QRGDPDEALS CLWQALATFE ELADERCAAY TLLEVGRVYA
GQHDRDRATP ALERAAHLFH RHGDRQDEAA CWQLIGDLDA AAGVHDLARR HHGRALRLWQ
TIGDMQQTKA PAPPSSP
//
