ID A0A176L5S3_9ACTN Unreviewed; 297 AA.
AC A0A176L5S3;
DT 07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT 07-SEP-2016, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE SubName: Full=NADPH:quinone reductase {ECO:0000313|EMBL:OAA99836.1};
GN ORFNames=A6P39_15440 {ECO:0000313|EMBL:OAA99836.1};
OS Streptomyces sp. FXJ1.172.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=710705 {ECO:0000313|EMBL:OAA99836.1};
RN [1] {ECO:0000313|EMBL:OAA99836.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=FXJ1.172 {ECO:0000313|EMBL:OAA99836.1};
RA Liu M., Liu N., Shang F., Huang Y.;
RT "Activation and identification of NC-1, a novel cryptic cyclodepsipeptide
RT from red soil-derived Streptomyces sp. FXJ1.172.";
RL Submitted (APR-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBUNIT: Homotetramer. {ECO:0000256|ARBA:ARBA00011881}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OAA99836.1}.
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DR EMBL; LWRP01000076; OAA99836.1; -; Genomic_DNA.
DR RefSeq; WP_067045554.1; NZ_CP119133.1.
DR AlphaFoldDB; A0A176L5S3; -.
DR STRING; 710705.A6P39_15440; -.
DR OrthoDB; 3727682at2; -.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR CDD; cd05289; MDR_like_2; 1.
DR Gene3D; 3.90.180.10; Medium-chain alcohol dehydrogenases, catalytic domain; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR013154; ADH-like_N.
DR InterPro; IPR011032; GroES-like_sf.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR020843; PKS_ER.
DR InterPro; IPR002364; Quin_OxRdtase/zeta-crystal_CS.
DR PANTHER; PTHR44154; QUINONE OXIDOREDUCTASE; 1.
DR PANTHER; PTHR44154:SF1; QUINONE OXIDOREDUCTASE; 1.
DR Pfam; PF08240; ADH_N; 1.
DR Pfam; PF13602; ADH_zinc_N_2; 1.
DR SMART; SM00829; PKS_ER; 1.
DR SUPFAM; SSF50129; GroES-like; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR PROSITE; PS01162; QOR_ZETA_CRYSTAL; 1.
PE 4: Predicted;
KW RNA-binding {ECO:0000256|ARBA:ARBA00022884}.
FT DOMAIN 10..295
FT /note="Enoyl reductase (ER)"
FT /evidence="ECO:0000259|SMART:SM00829"
SQ SEQUENCE 297 AA; 30491 MW; B6B55220B69BCCD2 CRC64;
MKRVSFAEFG GPDVLRLLDA EEPHAGPGQV RIAVRAAGVN PVDWRIREGQ ILGAHPVELP
SGVGLDASGV VDEVGEGVAG VGVGDHVFGE GSSTYAEFAV LSAWARMPEG LTFEEAAGYP
SVVETALRII REVGVRSGQT LLVSGAAGGV GSAVLQIARD RGITVIGTAG AANQDYLRGL
GALATTYGEG WVARVRRLGH VDAALDLAGS GVIRELVGLT GDPRKVISIA DLGAPALGVR
FSGVAGSMPE ALAEAVGLIS RGKLRIPVEK SYPLAEAAAA HMDSQSGHTR GRRVLVI
//
