ID A0A176LD03_9ACTN Unreviewed; 466 AA.
AC A0A176LD03;
DT 07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT 07-SEP-2016, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=F420-dependent methylene-tetrahydromethanopterin reductase {ECO:0000313|EMBL:OAB02362.1};
GN ORFNames=A6P39_02195 {ECO:0000313|EMBL:OAB02362.1};
OS Streptomyces sp. FXJ1.172.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=710705 {ECO:0000313|EMBL:OAB02362.1};
RN [1] {ECO:0000313|EMBL:OAB02362.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=FXJ1.172 {ECO:0000313|EMBL:OAB02362.1};
RA Liu M., Liu N., Shang F., Huang Y.;
RT "Activation and identification of NC-1, a novel cryptic cyclodepsipeptide
RT from red soil-derived Streptomyces sp. FXJ1.172.";
RL Submitted (APR-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the NtaA/SnaA/DszA monooxygenase family.
CC {ECO:0000256|ARBA:ARBA00033748}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OAB02362.1}.
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DR EMBL; LWRP01000016; OAB02362.1; -; Genomic_DNA.
DR RefSeq; WP_067039092.1; NZ_CP119133.1.
DR AlphaFoldDB; A0A176LD03; -.
DR STRING; 710705.A6P39_02195; -.
DR OrthoDB; 9135350at2; -.
DR GO; GO:0004497; F:monooxygenase activity; IEA:InterPro.
DR GO; GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro.
DR CDD; cd01095; Nitrilotriacetate_monoxgenase; 1.
DR Gene3D; 3.20.20.30; Luciferase-like domain; 1.
DR InterPro; IPR011251; Luciferase-like_dom.
DR InterPro; IPR036661; Luciferase-like_sf.
DR InterPro; IPR016215; NTA_MOA.
DR NCBIfam; TIGR03860; FMN_nitrolo; 1.
DR PANTHER; PTHR30011; ALKANESULFONATE MONOOXYGENASE-RELATED; 1.
DR PANTHER; PTHR30011:SF16; C2H2 FINGER DOMAIN TRANSCRIPTION FACTOR (EUROFUNG)-RELATED; 1.
DR Pfam; PF00296; Bac_luciferase; 1.
DR PIRSF; PIRSF000337; NTA_MOA; 1.
DR SUPFAM; SSF51679; Bacterial luciferase-like; 1.
PE 3: Inferred from homology;
KW Flavoprotein {ECO:0000256|PIRSR:PIRSR000337-1};
KW FMN {ECO:0000256|PIRSR:PIRSR000337-1}.
FT DOMAIN 34..402
FT /note="Luciferase-like"
FT /evidence="ECO:0000259|Pfam:PF00296"
FT BINDING 105
FT /ligand="FMN"
FT /ligand_id="ChEBI:CHEBI:58210"
FT /evidence="ECO:0000256|PIRSR:PIRSR000337-1"
FT BINDING 155
FT /ligand="FMN"
FT /ligand_id="ChEBI:CHEBI:58210"
FT /evidence="ECO:0000256|PIRSR:PIRSR000337-1"
FT BINDING 159
FT /ligand="FMN"
FT /ligand_id="ChEBI:CHEBI:58210"
FT /evidence="ECO:0000256|PIRSR:PIRSR000337-1"
FT BINDING 230
FT /ligand="FMN"
FT /ligand_id="ChEBI:CHEBI:58210"
FT /evidence="ECO:0000256|PIRSR:PIRSR000337-1"
SQ SEQUENCE 466 AA; 50949 MW; 7AFA8A37C303599D CRC64;
MTRTDPLDVP RPHAQLHFGV FFQGVNHWTI WSAPDSGSQI DPASFRRVAQ TAERGLFDAF
FLGEGLRLRE VDGRIHDLDV AGRPDAITQL AALAAVTHQI GLVSTSNSTF NEPADLARRL
SGLDLLSEGR AGWNVVTTDN AWTGANFRRG GYLDHADRYR RAEEFLTVAR ALWDGWGDGA
IADSAGAREW SVPGAVHRVR HRGAQFDVDL APTLPRSAQG HPVIFQAGDS GEGRDFAARN
ADVIFSAHGN VFDDALAFAE DIRTRLRAVG RPDDDLRILP GTEIIIGATE EEAQEKKRWI
RLQQVTPATA LGIAGLLWGI DLSDRDADGP LPNEDPVVTE NDGSFGARRI TDPRAVVAEW
RAKAEAHGWS LRETVIALGP QRGHVGTPSG LADKFAHFVR HGAIDGFNVT PYLIPDGLDD
IVDLLVPELQ DRGIYRTEYS GTTLREHLGL RAPLTHRSAP DRRQAG
//
