ID A0A176QBB9_9MICO Unreviewed; 831 AA.
AC A0A176QBB9;
DT 07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT 07-SEP-2016, sequence version 1.
DT 27-MAR-2024, entry version 30.
DE RecName: Full=histidine kinase {ECO:0000256|ARBA:ARBA00012438};
DE EC=2.7.13.3 {ECO:0000256|ARBA:ARBA00012438};
GN ORFNames=AWH69_11610 {ECO:0000313|EMBL:OAB87023.1};
OS Janibacter melonis.
OC Bacteria; Actinomycetota; Actinomycetes; Micrococcales; Intrasporangiaceae;
OC Janibacter.
OX NCBI_TaxID=262209 {ECO:0000313|EMBL:OAB87023.1, ECO:0000313|Proteomes:UP000076976};
RN [1] {ECO:0000313|EMBL:OAB87023.1, ECO:0000313|Proteomes:UP000076976}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CD11-4 {ECO:0000313|EMBL:OAB87023.1,
RC ECO:0000313|Proteomes:UP000076976};
RA Nair G.R., Kaur G., Chander A.M., Mayilraj S.;
RT "Janibacter melonis strain CD11_4 genome sequencing and assembly.";
RL Submitted (JAN-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + protein L-histidine = ADP + protein N-phospho-L-
CC histidine.; EC=2.7.13.3; Evidence={ECO:0000256|ARBA:ARBA00000085};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OAB87023.1}.
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DR EMBL; LQZG01000003; OAB87023.1; -; Genomic_DNA.
DR RefSeq; WP_068275675.1; NZ_LQZG01000003.1.
DR AlphaFoldDB; A0A176QBB9; -.
DR STRING; 262209.AWH69_11610; -.
DR Proteomes; UP000076976; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR CDD; cd00075; HATPase; 1.
DR CDD; cd00082; HisKA; 1.
DR CDD; cd01987; USP_OKCHK; 1.
DR Gene3D; 1.10.287.130; -; 1.
DR Gene3D; 1.20.120.620; Backbone structure of the membrane domain of e. Coli histidine kinase receptor kdpd; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR Gene3D; 3.40.50.620; HUPs; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR005467; His_kinase_dom.
DR InterPro; IPR003661; HisK_dim/P.
DR InterPro; IPR036097; HisK_dim/P_sf.
DR InterPro; IPR038318; KdpD_sf.
DR InterPro; IPR025201; KdpD_TM.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR014729; Rossmann-like_a/b/a_fold.
DR InterPro; IPR004358; Sig_transdc_His_kin-like_C.
DR InterPro; IPR003852; Sig_transdc_His_kinase_KdpD_N.
DR InterPro; IPR006016; UspA.
DR PANTHER; PTHR45569; SENSOR PROTEIN KDPD; 1.
DR PANTHER; PTHR45569:SF1; SENSOR PROTEIN KDPD; 1.
DR Pfam; PF13493; DUF4118; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF00512; HisKA; 1.
DR Pfam; PF02702; KdpD; 1.
DR Pfam; PF00582; Usp; 1.
DR PRINTS; PR00344; BCTRLSENSOR.
DR SMART; SM00387; HATPase_c; 1.
DR SMART; SM00388; HisKA; 1.
DR SUPFAM; SSF52402; Adenine nucleotide alpha hydrolases-like; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF47384; Homodimeric domain of signal transducing histidine kinase; 1.
DR PROSITE; PS50109; HIS_KIN; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Kinase {ECO:0000256|ARBA:ARBA00022777, ECO:0000313|EMBL:OAB87023.1};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000076976};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius};
KW Two-component regulatory system {ECO:0000256|ARBA:ARBA00023012}.
FT TRANSMEM 379..399
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 411..444
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 456..475
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 612..825
FT /note="Histidine kinase"
FT /evidence="ECO:0000259|PROSITE:PS50109"
SQ SEQUENCE 831 AA; 87797 MW; 6D8BE291B7359DCA CRC64;
MTRGRLRVLL GAAPGVGKTC TMLEEGRRLR ADGRDVVVGL VETHGRAATA AMVEGLEVVP
RTLVTHRGLE LAEMDLEAVL ARAPQVALVD ELAHTNAPGS HHAKRWQDVD ALLDAGVDVI
TTVNIQHIES LHDVVEQITG VPQSETTPDA FLRRADQVEV VDLAPQALRD RLLGGVVYPA
ERVDAALSNY FRLGNLIALR ELALLWLADE VDEALRRYRD EHDIDATWQA RERVVVALTG
GPEGETLLRR GARIAARSSG GGLHAVHVTA QDGLRAPDPA ALVQQRALVE QLGGSYHQVV
GDDVPAALVD FARSVDATQL VIGVSRRGRL AAALTGPGIG ATVVRESGDI DVHIVTHSAA
GGRFALPPVG GALSLRRRAL GMLLALLGGP LLTWLLVALR SPESITSDVL SYQLLVVVVA
LVGGLWPALF AAVLSAVTLD FFFIDPLYTV TIADPLHLLA LLLYVTIAAL VSVVVDRAAR
RSRTARRAAA ESELVQTVAG SVVRGDDAVQ ALVDQTREAL HLRGARVLAG EEVLASAGEV
DLAGAAPVST LELAPGTTLE LTGEVAASER RLLGVVAAQL TAALEHQRLT ETAREIEPIA
ASDRVRGALL SALSHDLRRP LAAATAAVGG VRAAGPDLRE EDRRELLDTA EESLAALSAL
MSDLLDVSRL SSGVLTIATT PTDPAEAIAP ALDELGLGPA QVRLALAHDE VEVLADPVLL
QRVVVNLLTN AVRHSPPDEP VLVSTSTFGG RLEIRVADRG PGIAQDRRDE VFLPFQRLGD
TDNTTGLGLG LALSRGFVEG MHGRLTPEDT PGGGLTMVVS LPVHDPSQEA R
//
