ID A0A176VSN1_MARPO Unreviewed; 691 AA.
AC A0A176VSN1;
DT 07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT 07-SEP-2016, sequence version 1.
DT 24-JAN-2024, entry version 21.
DE RecName: Full=isocitrate lyase {ECO:0000256|ARBA:ARBA00012909};
DE EC=4.1.3.1 {ECO:0000256|ARBA:ARBA00012909};
GN ORFNames=AXG93_1544s1210 {ECO:0000313|EMBL:OAE23085.1};
OS Marchantia polymorpha subsp. ruderalis.
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Marchantiophyta;
OC Marchantiopsida; Marchantiidae; Marchantiales; Marchantiaceae; Marchantia.
OX NCBI_TaxID=1480154 {ECO:0000313|EMBL:OAE23085.1, ECO:0000313|Proteomes:UP000077202};
RN [1] {ECO:0000313|EMBL:OAE23085.1, ECO:0000313|Proteomes:UP000077202}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Tak-1 and cv. Tak-2 {ECO:0000313|Proteomes:UP000077202};
RC TISSUE=Whole gametophyte {ECO:0000313|EMBL:OAE23085.1};
RA Honkanen S., Jones V.A., Morieri G., Champion C., Hetherington A.J.,
RA Kelly S., Saint-Marcoux D., Proust H., Prescott H., Dolan L.;
RT "Mechanisms controlling the formation of the plant cell surface in tip-
RT growing cells are functionally conserved among land plants.";
RL Submitted (MAR-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Involved in storage lipid mobilization during the growth of
CC higher plant seedling. {ECO:0000256|ARBA:ARBA00003575}.
CC -!- PATHWAY: Carbohydrate metabolism; glyoxylate cycle; (S)-malate from
CC isocitrate: step 1/2. {ECO:0000256|ARBA:ARBA00004793}.
CC -!- SUBCELLULAR LOCATION: Glyoxysome {ECO:0000256|ARBA:ARBA00004130}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OAE23085.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; LVLJ01002948; OAE23085.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A176VSN1; -.
DR OrthoDB; 983054at2759; -.
DR UniPathway; UPA00703; UER00719.
DR Proteomes; UP000077202; Unassembled WGS sequence.
DR GO; GO:0009514; C:glyoxysome; IEA:UniProtKB-SubCell.
DR GO; GO:0004451; F:isocitrate lyase activity; IEA:InterPro.
DR GO; GO:0006097; P:glyoxylate cycle; IEA:UniProtKB-UniPathway.
DR GO; GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-KW.
DR CDD; cd00377; ICL_PEPM; 1.
DR Gene3D; 1.10.10.850; -; 1.
DR Gene3D; 3.20.20.60; Phosphoenolpyruvate-binding domains; 1.
DR InterPro; IPR039556; ICL/PEPM.
DR InterPro; IPR006254; Isocitrate_lyase.
DR InterPro; IPR018523; Isocitrate_lyase_ph_CS.
DR InterPro; IPR015813; Pyrv/PenolPyrv_Kinase-like_dom.
DR InterPro; IPR040442; Pyrv_Kinase-like_dom_sf.
DR NCBIfam; TIGR01346; isocit_lyase; 1.
DR PANTHER; PTHR21631:SF3; BIFUNCTIONAL GLYOXYLATE CYCLE PROTEIN; 1.
DR PANTHER; PTHR21631; ISOCITRATE LYASE/MALATE SYNTHASE; 1.
DR Pfam; PF00463; ICL; 1.
DR SUPFAM; SSF51621; Phosphoenolpyruvate/pyruvate domain; 1.
DR PROSITE; PS00161; ISOCITRATE_LYASE; 1.
PE 4: Predicted;
KW Glyoxylate bypass {ECO:0000256|ARBA:ARBA00022435};
KW Glyoxysome {ECO:0000256|ARBA:ARBA00022453};
KW Lyase {ECO:0000256|ARBA:ARBA00023239};
KW Reference proteome {ECO:0000313|Proteomes:UP000077202};
KW Tricarboxylic acid cycle {ECO:0000256|ARBA:ARBA00022532}.
SQ SEQUENCE 691 AA; 76242 MW; 2AD64FE99585EC14 CRC64;
MAREIGDASM AMVIGGLGKK ILRFAVVAER DGGSRNRSST LTILVFEFGR GESGELYTLF
FDCLDESGSL DLILQLLTSE PITSSSFGPK VSSLQFSLSW PNSTPAVPAA NQTPRIAQIS
RYTVPGNASL LLFERGKKAP LRISVAQEEL EFQNQVREIK QWWGSERFQH TTRPYTAESV
AKLRGSLPQH YASSEQAKKL YALLRRHQAN KTCSRTFGAL DPVQVAQMGK YLDSIYVSGW
QCASTASTSN EPGPDLADYP MDTVPNKVEH LFFAQCFHDR KQREARLNMS KEQRLATPYV
DYLAPLIADG DTGFGATTAT VKLMKMFVER GAAGVHMEDQ SSTTKKCGHM GGKVLVPTQE
HINRLIAARL QFDVMGVEQV LVARTDSEAA SLLMSNIDAR DHPFILGASN PAVKGKSLVQ
VVQAAAAKGA TGAQLQALES EWKAQARVCL FSDLVAEKIQ ALAISSQEKS SRTAQWLAKV
GDLSHDQARE LAASLGVTDV FWCWDLPRTR EGYYRYLGGT KAAIARGIAF APYADLIWME
TAKPDYKQAK EFALGVKAKY PHQMLAYNQS PSFNWDAANM TDKEFEEYIP KLAELGFVWQ
FITLAGFHAD ALITDKFARA YAQEGMLAYV RDIQRQERVH GVETLAHQTW SGASYYDQIL
QTVSGGYSST AAMGHGVTED QFKQGPKNAK L
//
