ID A0A176VXH6_MARPO Unreviewed; 998 AA.
AC A0A176VXH6;
DT 07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT 07-SEP-2016, sequence version 1.
DT 22-FEB-2023, entry version 19.
DE RecName: Full=ER membrane protein complex subunit 1 {ECO:0000256|ARBA:ARBA00020824};
GN ORFNames=AXG93_4094s1010 {ECO:0000313|EMBL:OAE25051.1};
OS Marchantia polymorpha subsp. ruderalis.
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Marchantiophyta;
OC Marchantiopsida; Marchantiidae; Marchantiales; Marchantiaceae; Marchantia.
OX NCBI_TaxID=1480154 {ECO:0000313|EMBL:OAE25051.1, ECO:0000313|Proteomes:UP000077202};
RN [1] {ECO:0000313|EMBL:OAE25051.1, ECO:0000313|Proteomes:UP000077202}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Tak-1 and cv. Tak-2 {ECO:0000313|Proteomes:UP000077202};
RC TISSUE=Whole gametophyte {ECO:0000313|EMBL:OAE25051.1};
RA Honkanen S., Jones V.A., Morieri G., Champion C., Hetherington A.J.,
RA Kelly S., Saint-Marcoux D., Proust H., Prescott H., Dolan L.;
RT "Mechanisms controlling the formation of the plant cell surface in tip-
RT growing cells are functionally conserved among land plants.";
RL Submitted (MAR-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBUNIT: Component of the ER membrane protein complex (EMC).
CC {ECO:0000256|ARBA:ARBA00011276}.
CC -!- SUBCELLULAR LOCATION: Endoplasmic reticulum membrane
CC {ECO:0000256|ARBA:ARBA00004115}; Single-pass type I membrane protein
CC {ECO:0000256|ARBA:ARBA00004115}. Membrane
CC {ECO:0000256|ARBA:ARBA00004479}; Single-pass type I membrane protein
CC {ECO:0000256|ARBA:ARBA00004479}.
CC -!- SIMILARITY: Belongs to the EMC1 family.
CC {ECO:0000256|ARBA:ARBA00007904}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OAE25051.1}.
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DR EMBL; LVLJ01002413; OAE25051.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A176VXH6; -.
DR OrthoDB; 37872at2759; -.
DR Proteomes; UP000077202; Unassembled WGS sequence.
DR GO; GO:0072546; C:EMC complex; IEA:InterPro.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 1.
DR InterPro; IPR026895; EMC1.
DR InterPro; IPR011678; EMC1_C.
DR InterPro; IPR002372; PQQ_repeat.
DR InterPro; IPR011047; Quinoprotein_ADH-like_supfam.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR PANTHER; PTHR21573:SF0; ER MEMBRANE PROTEIN COMPLEX SUBUNIT 1; 1.
DR PANTHER; PTHR21573; UNCHARACTERIZED; 1.
DR Pfam; PF07774; EMC1_C; 1.
DR Pfam; PF13360; PQQ_2; 1.
DR SUPFAM; SSF50998; Quinoprotein alcohol dehydrogenase-like; 1.
PE 3: Inferred from homology;
KW Endoplasmic reticulum {ECO:0000256|ARBA:ARBA00022824};
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000077202};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..25
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 26..998
FT /note="ER membrane protein complex subunit 1"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5008052171"
FT TRANSMEM 965..988
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 781..997
FT /note="ER membrane protein complex subunit 1 C-terminal"
FT /evidence="ECO:0000259|Pfam:PF07774"
SQ SEQUENCE 998 AA; 110465 MW; 77C46C9D55ECCC93 CRC64;
MNLQVLQQTA LGVLILCSIW ICCDALYEDQ VGVWDWHQQY IGKVKHAVFQ TQGSGRKRVI
VGTEEDAIAS LNLRTGEVYW RRVLGEGDSV NALDIINGKY VISLSKDGSN VRAWHLPDGA
LVWESLLLPS MGSVASLLVL PVDINNDRMN DMLIFSGSML YALSCHDGGI IWKADLQALR
EDLVIKKVSL SSDGTLFGVG FSDVSGLVIV EIDLRFGHIR KINPVGISKA LDTKELMLVN
GVAVALDAAF TTVVTALIKT GGDVKIVETL LSDLVSAEVK SAQILSTTLE GAVAFQVNGK
VVVVKVDSAT GQLDVLEVFE SSVVLSNSLN VVESKHATAI VEPTEDGGSI GKFSLRVVYA
NSWSVDAAKD SVSLESHRGL IRKVFLNAYL RTDRSYGFRA LVVGEDDSLS LLQQGEVVWT
REDGLASIID TWTSELPLER DRHPVSEVEH DLADWLRGHW LKLKATLFLA SAEELAAVQA
LRLHSSDKTK MARDHNGFRK LLIVLTKAGK VIALHTGDGR IVWSVLLPSL RAESGISKVP
LKLMPWQVPH QHALDENPVV LVVGRSKGIS DSTGILSWVD VYKGKELRSS KLNFPVKLMI
PLPFTDTSEQ RLHLFIDDKQ KAHVFPATEE SLSLFLKHKA NVVYHIVDKE KGTIVGYTIK
NMVDGITEGE TDGHVFHTEP IWSVIFPSET EVISTVVTRR PDEAVHTQSK ILGSRDVLYK
YLNKNMIFVA TVTPKAAQHI GSATPEEAGL VAYLIDTVTG RVLHRVSHPF MQGPVHAVFN
ENWVVYHYFN LKMYRYEMSV IEIYDQNRMG DKGVLQLMLG RHNASSPVSS YSIPSIEVKT
QTYFFTFSVK AMTVTSTARG ITGKHILVGT VNDQVLALDK RFFDPRRTVS PSQAEREEGI
IPLTDAIPIF PQSYITHVHQ VEGLRGILTV PARLESTSLV FTYGLDLFFT RTAPSRTYDS
LTEDFSYALL LITIVALIIG IVVTWILSER KELGEKWK
//
