ID A0A177D328_ALTAL Unreviewed; 510 AA.
AC A0A177D328;
DT 07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT 07-SEP-2016, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE SubName: Full=S-adenosyl-L-methionine-dependent methyltransferase {ECO:0000313|EMBL:OAG13861.1};
GN ORFNames=AA0117_g11038 {ECO:0000313|EMBL:RYN69135.1},
GN CC77DRAFT_1026276 {ECO:0000313|EMBL:OAG13861.1};
OS Alternaria alternata (Alternaria rot fungus) (Torula alternata).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Dothideomycetes;
OC Pleosporomycetidae; Pleosporales; Pleosporineae; Pleosporaceae; Alternaria;
OC Alternaria sect. Alternaria; Alternaria alternata complex.
OX NCBI_TaxID=5599 {ECO:0000313|EMBL:OAG13861.1, ECO:0000313|Proteomes:UP000077248};
RN [1] {ECO:0000313|EMBL:OAG13861.1, ECO:0000313|Proteomes:UP000077248}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SRC1lrK2f {ECO:0000313|EMBL:OAG13861.1,
RC ECO:0000313|Proteomes:UP000077248};
RG DOE Joint Genome Institute;
RA Zeiner C.A., Purvine S.O., Zink E.M., Wu S., Pasa-Tolic L., Chaput D.L.,
RA Haridas S., Grigoriev I.V., Santelli C.M., Hansel C.M.;
RT "Comparative analysis of secretome profiles of manganese(II)-oxidizing
RT ascomycete fungi.";
RL Submitted (MAY-2016) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000291422}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=FERA 1177 {ECO:0000313|Proteomes:UP000291422};
RA Armitage A.D., Cockerton H.M., Sreenivasaprasad S., Woodhall J., Lane C.,
RA Harrison R.J., Clarkson J.P.;
RT "Genomics, evolutionary history and diagnostics of the Alternaria alternata
RT species group including apple and Asian pear pathotypes.";
RL bioRxiv 0:0-0(2019).
RN [3] {ECO:0000313|EMBL:RYN69135.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=FERA 1177 {ECO:0000313|EMBL:RYN69135.1};
RA Armitage A.D., Cockerton H.M., Sreenivasaprasad S., Woodhall J., Lane C.,
RA Harrison R.J., Clarkson J.P.;
RT "Genomics, evolutionary history and diagnostics of the Alternaria alternata
RT species group including apple and Asian pear pathotypes.";
RL J. ISSAAS 0:0-0(2019).
CC -!- SIMILARITY: Belongs to the methyltransferase superfamily. METL family.
CC {ECO:0000256|ARBA:ARBA00009725}.
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DR EMBL; KV441505; OAG13861.1; -; Genomic_DNA.
DR EMBL; PDXD01000046; RYN69135.1; -; Genomic_DNA.
DR RefSeq; XP_018379282.1; XM_018526224.1.
DR STRING; 5599.A0A177D328; -.
DR GeneID; 29111818; -.
DR KEGG; aalt:CC77DRAFT_1026276; -.
DR VEuPathDB; FungiDB:CC77DRAFT_1026276; -.
DR OMA; MFLFRDY; -.
DR OrthoDB; 5471626at2759; -.
DR Proteomes; UP000077248; Unassembled WGS sequence.
DR Proteomes; UP000291422; Unassembled WGS sequence.
DR GO; GO:0008173; F:RNA methyltransferase activity; IEA:UniProt.
DR GO; GO:0008757; F:S-adenosylmethionine-dependent methyltransferase activity; IEA:UniProt.
DR GO; GO:0001510; P:RNA methylation; IEA:UniProt.
DR CDD; cd02440; AdoMet_MTases; 1.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR InterPro; IPR013217; Methyltransf_12.
DR InterPro; IPR026113; METTL2/6/8-like.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR PANTHER; PTHR22809:SF11; METHYLTRANSFERASE-LIKE PROTEIN; 1.
DR PANTHER; PTHR22809; METHYLTRANSFERASE-RELATED; 1.
DR Pfam; PF08242; Methyltransf_12; 1.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
PE 3: Inferred from homology;
KW Methyltransferase {ECO:0000313|EMBL:OAG13861.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000077248};
KW Transferase {ECO:0000313|EMBL:OAG13861.1}.
FT DOMAIN 214..322
FT /note="Methyltransferase type 12"
FT /evidence="ECO:0000259|Pfam:PF08242"
FT REGION 1..115
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 406..433
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 466..510
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 10..39
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 56..81
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 406..426
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 510 AA; 57404 MW; A3FCDEE7C3C803C2 CRC64;
MDAMESANTD AMDGPSSQDS GDSRFQTDNS MSRKPQPKQQ LSKAMEHMRF AVTVDPIPHT
STSTPPPEAS DAASPPTQQG PENDAYGVPA SLQPVRAPPS RSHDPGNNQK RSDPFAFGSR
YLEEGDNIFE FNAWDHVTVD SNYLAFSEEQ YSKQRQEPVS EFDRKRYNDQ PEKWWNQFYK
NNKTNFFKNR KWLAQEFPIL EELGAEDGPE ATLLEVGAGA GNSAFPILQR SQNKRLKIHA
CDFSKKAVEL IRNHELYDPE RIQADVWDVA ASPDSENGGL PPGLIEGSVD VVLMIFIFSA
LNPKQWDQAV RNIWRVLKPG GQVLFRDYGR GDLAQVRFKK GRYMEENFYV RGDGTRVYFF
EQSELEDIWG GAARKRDTTV GNVADTTISQ TEAEGVIADK IESLSLHDPD SQTREQSHDD
VNDPETPRPG FEVAHIGVDR RMLVNRQRRL KMYRCWMQAV FRKAGMESEV PTSTLRQDKE
EEEGGDGVAD EQGESQASKE DAVEGGGVKV
//
