ID   A0A177DK28_ALTAL        Unreviewed;       969 AA.
AC   A0A177DK28;
DT   07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT   07-SEP-2016, sequence version 1.
DT   27-MAR-2024, entry version 28.
DE   RecName: Full=Pep3/Vps18/deep orange beta-propeller domain-containing protein {ECO:0000259|Pfam:PF05131};
GN   ORFNames=CC77DRAFT_990648 {ECO:0000313|EMBL:OAG19717.1};
OS   Alternaria alternata (Alternaria rot fungus) (Torula alternata).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Dothideomycetes;
OC   Pleosporomycetidae; Pleosporales; Pleosporineae; Pleosporaceae; Alternaria;
OC   Alternaria sect. Alternaria; Alternaria alternata complex.
OX   NCBI_TaxID=5599 {ECO:0000313|EMBL:OAG19717.1, ECO:0000313|Proteomes:UP000077248};
RN   [1] {ECO:0000313|EMBL:OAG19717.1, ECO:0000313|Proteomes:UP000077248}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=SRC1lrK2f {ECO:0000313|EMBL:OAG19717.1,
RC   ECO:0000313|Proteomes:UP000077248};
RG   DOE Joint Genome Institute;
RA   Zeiner C.A., Purvine S.O., Zink E.M., Wu S., Pasa-Tolic L., Chaput D.L.,
RA   Haridas S., Grigoriev I.V., Santelli C.M., Hansel C.M.;
RT   "Comparative analysis of secretome profiles of manganese(II)-oxidizing
RT   ascomycete fungi.";
RL   Submitted (MAY-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004287};
CC       Peripheral membrane protein {ECO:0000256|ARBA:ARBA00004287};
CC       Cytoplasmic side {ECO:0000256|ARBA:ARBA00004287}.
CC   -!- SIMILARITY: Belongs to the VPS18 family.
CC       {ECO:0000256|ARBA:ARBA00010454}.
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DR   EMBL; KV441480; OAG19717.1; -; Genomic_DNA.
DR   RefSeq; XP_018385138.1; XM_018536324.1.
DR   AlphaFoldDB; A0A177DK28; -.
DR   STRING; 5599.A0A177DK28; -.
DR   GeneID; 29121918; -.
DR   KEGG; aalt:CC77DRAFT_990648; -.
DR   VEuPathDB; FungiDB:CC77DRAFT_990648; -.
DR   OMA; WIQREKW; -.
DR   OrthoDB; 22879at2759; -.
DR   Proteomes; UP000077248; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006886; P:intracellular protein transport; IEA:UniProtKB-UniRule.
DR   GO; GO:0016192; P:vesicle-mediated transport; IEA:InterPro.
DR   CDD; cd16462; RING-H2_Pep3p-like; 1.
DR   InterPro; IPR000547; Clathrin_H-chain/VPS_repeat.
DR   InterPro; IPR007810; Pep3_Vps18.
DR   PANTHER; PTHR23323; VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN; 1.
DR   PANTHER; PTHR23323:SF26; VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 18 HOMOLOG; 1.
DR   Pfam; PF00637; Clathrin; 1.
DR   Pfam; PF05131; Pep3_Vps18; 1.
DR   SUPFAM; SSF57850; RING/U-box; 1.
DR   PROSITE; PS50236; CHCR; 1.
PE   3: Inferred from homology;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Reference proteome {ECO:0000313|Proteomes:UP000077248};
KW   Zinc {ECO:0000256|ARBA:ARBA00022833};
KW   Zinc-finger {ECO:0000256|ARBA:ARBA00022771}.
FT   DOMAIN          24..437
FT                   /note="Pep3/Vps18/deep orange beta-propeller"
FT                   /evidence="ECO:0000259|Pfam:PF05131"
FT   REGION          1..21
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          817..858
FT                   /evidence="ECO:0000256|SAM:Coils"
SQ   SEQUENCE   969 AA;  108733 MW;  D9FE1A5A220A8271 CRC64;
     MAYDTSSGYA PPSTSNMQED ASGPMFNIER VTLQFNISSD FVAAAVANNV VVLALSTGRI
     LRIDLDSPAD IDDIDLPKKP SEVGVIRRLF LDPSASHLIV TTTLAENYYL HTQSRTPKAL
     SRLKGVVIES ISWNPSQPTA STREILVGAS DGNVYEVYIE PSSEFYRREE RYLKSVYRTN
     DGPITGLWTD MVPGRTDLRR IIVATPSTFL HFAGKVGRQG SEGSGSIFSK LFESESATVH
     EVSNVASTAT SLLSVSPENQ ENPNREESNA ERIFGWLTSQ GVLHGKLYLS QDTSELGSKV
     LGDAKMLPRS QVPPSQTASG RTRRTQDAVS SMILSQWHIL QLVEGRIVAI NRLDDTVVLD
     QVVLEPGQSA LGLVVDLKKN TYWLFTTQEI FEIVVTDESR DVWKIMLRAQ QFEAASQYAK
     TPAQKDAVAT ASGDYLVGKS QWMEAATVYG RSTKPFEQVA LTFIDNGEQD ALRKYLVTKL
     STLKKSSIMQ RTMVATWLIE LYMAKLNTLD DTITTKAELS ESMNTAETHD QLSVIRKEYQ
     DFVSKYKADL DRKTVYEIIS SHGREEELLY FATVVNDYNY VLSYWVQRER WQESLDVLKK
     QTDPEIFYKY SSVLMAHVPV ELVDIMMRHS TFDAQKLIPA FLNYNNHTKA SLAQNQAVRY
     LLFEINQHNS TDAAIHNTLI SIYASHPTPD ESALLAYLEG QSLAHEQNYD ADFALRLCIQ
     HKRVQSCVHI YSSMQQYVQA VDLALKYDEV DLASTVADRS NTSPPLRKKL WLAIAKKVIS
     QSSGIKTAIE FLRRVDLLRI EDLIPFFPDF VVIDDFKEEI CAALEDYSHK IDSLKQEMDD
     SEATATHIKS DIKALEQRYA IVEPGERCYV CGLPLLARQF FVFPCQHAFH SDCLAKRVVE
     LAGIARGKRI AELQAEVQRG VKVGKGRERA IRELDALVGS SCVLCGELAV KLVNEPFISA
     TDDKDEWAL
//