ID A0A177EPY6_9MICR Unreviewed; 442 AA.
AC A0A177EPY6;
DT 07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT 07-SEP-2016, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE RecName: Full=FAD-binding FR-type domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=NEIG_01597 {ECO:0000313|EMBL:OAG33172.1};
OS Nematocida sp. ERTm5.
OC Eukaryota; Fungi; Fungi incertae sedis; Microsporidia; Nematocida.
OX NCBI_TaxID=1805481 {ECO:0000313|EMBL:OAG33172.1, ECO:0000313|Proteomes:UP000077089};
RN [1] {ECO:0000313|EMBL:OAG33172.1, ECO:0000313|Proteomes:UP000077089}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ERTm5 {ECO:0000313|EMBL:OAG33172.1,
RC ECO:0000313|Proteomes:UP000077089};
RA Reinke A.W., Balla K.M., Bennett E.J., Troemel E.R.;
RT "Identification of microsporidia host-exposed proteins reveals a repertoire
RT of large paralogous families and rapidly evolving proteins.";
RL Submitted (FEB-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=FAD; Xref=ChEBI:CHEBI:57692;
CC Evidence={ECO:0000256|ARBA:ARBA00001974};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OAG33172.1}.
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DR EMBL; LTDK01000083; OAG33172.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A177EPY6; -.
DR VEuPathDB; MicrosporidiaDB:NEIG_01597; -.
DR OrthoDB; 9164at2759; -.
DR Proteomes; UP000077089; Unassembled WGS sequence.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR Gene3D; 3.40.50.80; Nucleotide-binding domain of ferredoxin-NADP reductase (FNR) module; 1.
DR Gene3D; 2.40.30.10; Translation factors; 1.
DR InterPro; IPR003097; CysJ-like_FAD-binding.
DR InterPro; IPR039261; FNR_nucleotide-bd.
DR InterPro; IPR023173; NADPH_Cyt_P450_Rdtase_alpha.
DR InterPro; IPR001433; OxRdtase_FAD/NAD-bd.
DR InterPro; IPR017938; Riboflavin_synthase-like_b-brl.
DR PANTHER; PTHR19384:SF10; NADPH-DEPENDENT DIFLAVIN OXIDOREDUCTASE 1; 1.
DR PANTHER; PTHR19384; NITRIC OXIDE SYNTHASE-RELATED; 1.
DR Pfam; PF00667; FAD_binding_1; 1.
DR Pfam; PF00175; NAD_binding_1; 1.
DR SUPFAM; SSF52343; Ferredoxin reductase-like, C-terminal NADP-linked domain; 1.
DR SUPFAM; SSF63380; Riboflavin synthase domain-like; 1.
PE 4: Predicted;
KW FAD {ECO:0000256|ARBA:ARBA00022827};
KW Flavoprotein {ECO:0000256|ARBA:ARBA00022630};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002}.
FT DOMAIN 87..231
FT /note="Sulfite reductase [NADPH] flavoprotein alpha-
FT component-like FAD-binding"
FT /evidence="ECO:0000259|Pfam:PF00667"
FT DOMAIN 312..418
FT /note="Oxidoreductase FAD/NAD(P)-binding"
FT /evidence="ECO:0000259|Pfam:PF00175"
SQ SEQUENCE 442 AA; 50377 MW; D99998EF8AAA6344 CRC64;
MKSKKLMNAW QKREVLLENY TEDRKKLLLR PIHSIEIKEG VVVSGLEYAD AYSDQCTGGN
ASDRLETYKL NTTEIYRGRQ CVIRGTVDGL KMKYTPGDSL LMWAPNSDEI VEVLMGLFNI
KEDKCVQFRR IRCRDSSLIF SFSGRISGYF KYFLDITSIP SKLALFRLSQ YAEKNKDQLE
YLSSKEGSGD YFALGRNWNT LIDILLQFRV KIPFEALLEV SKEIKPRAFS FINGEDDDCE
FVAGILTDTE SPVRNGHFSD FLLRNTGNKA ETMGTSLIQK KFMDCIYRVK HKENNLFKLR
SSSTVCLLFG IGTGVAPFIS FIRNCRKDCQ FTLFYGCKSS EENILVKTSI AHGKEHPSEY
TGAFLLKTEC PNVEVHVVYS QTHLSIRMGE FLEKNAAQVQ KKCAELSLDG IYICGNKEAT
KSISNYFAVN HPEVLLHSDD WS
//
