ID A0A177HVN8_9ACTN Unreviewed; 508 AA.
AC A0A177HVN8;
DT 07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT 07-SEP-2016, sequence version 1.
DT 24-JAN-2024, entry version 20.
DE SubName: Full=Oxygen-dependent choline dehydrogenase {ECO:0000313|EMBL:OAH14294.1};
DE EC=1.1.99.1 {ECO:0000313|EMBL:OAH14294.1};
DE EC=1.2.1.8 {ECO:0000313|EMBL:OAH14294.1};
GN Name=betA_1 {ECO:0000313|EMBL:OAH14294.1};
GN ORFNames=STSP_23550 {ECO:0000313|EMBL:OAH14294.1};
OS Streptomyces jeddahensis.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1716141 {ECO:0000313|EMBL:OAH14294.1, ECO:0000313|Proteomes:UP000077381};
RN [1] {ECO:0000313|EMBL:OAH14294.1, ECO:0000313|Proteomes:UP000077381}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=G25(2015) {ECO:0000313|Proteomes:UP000077381};
RA Poehlein A., Roettig A., Hiessl S., Hauschild P., Schauer J., Madkour M.H.,
RA Al-Ansari A.M., Almakishah N.H., Steinbuechel A., Daniel R.;
RT "Genome sequence of Streptomyces sp. G25.";
RL Submitted (DEC-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=FAD; Xref=ChEBI:CHEBI:57692;
CC Evidence={ECO:0000256|ARBA:ARBA00001974};
CC -!- SIMILARITY: Belongs to the GMC oxidoreductase family.
CC {ECO:0000256|ARBA:ARBA00010790}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OAH14294.1}.
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DR EMBL; LOHS01000067; OAH14294.1; -; Genomic_DNA.
DR RefSeq; WP_067275667.1; NZ_LOHS01000067.1.
DR AlphaFoldDB; A0A177HVN8; -.
DR STRING; 1716141.STSP_23550; -.
DR PATRIC; fig|1716141.3.peg.2480; -.
DR OrthoDB; 9798604at2; -.
DR Proteomes; UP000077381; Unassembled WGS sequence.
DR GO; GO:0008802; F:betaine-aldehyde dehydrogenase activity; IEA:UniProtKB-EC.
DR GO; GO:0008812; F:choline dehydrogenase activity; IEA:UniProtKB-EC.
DR GO; GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.
DR Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 2.
DR InterPro; IPR036188; FAD/NAD-bd_sf.
DR InterPro; IPR000172; GMC_OxRdtase_N.
DR InterPro; IPR007867; GMC_OxRtase_C.
DR PANTHER; PTHR42784; PYRANOSE 2-OXIDASE; 1.
DR PANTHER; PTHR42784:SF1; PYRANOSE 2-OXIDASE; 1.
DR Pfam; PF05199; GMC_oxred_C; 1.
DR Pfam; PF00732; GMC_oxred_N; 1.
DR SUPFAM; SSF54373; FAD-linked reductases, C-terminal domain; 1.
DR SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
PE 3: Inferred from homology;
KW Oxidoreductase {ECO:0000313|EMBL:OAH14294.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000077381}.
FT DOMAIN 226..294
FT /note="Glucose-methanol-choline oxidoreductase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF00732"
FT DOMAIN 374..494
FT /note="Glucose-methanol-choline oxidoreductase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF05199"
SQ SEQUENCE 508 AA; 53178 MW; 2998379781EE906E CRC64;
MTGTSRTGVL IVGSGIMGSV VSRLLRDTDP TLDITMVDGG QPIGSAPGLH LHDLDDPALW
SRYNERVATG IQGLYTGAEV VRDVADSITG LAPGMFHALA FGEDAEAMPA AALAWNAGGM
GVHWTAATPW PAGDEVFDFG DPGHWATDLD TARRLLAVTP AAIGPTPVGQ RVLDVLRRRY
DGVGPDDRRC QPMPMAVTAT PAGPMPRTAP GTVFPAIATG GDPAFTLLTG TLATALVTEG
GRVAGARLRR VADGAECELL ADTVVVCADA LRTPQLLFAS GIRPAALGRH LNEHAFISAR
VLLDLDRFGI GLDALPLPRP GEFATDSLWL PQNGAAQPFH GQIMNRTYVD EAGRPLAHSV
GLSLYAPLES RPENRLVFSE SDTDLAGMPR FTVEFGYSDA DRELISRALD QVRSLAEEFG
TFDPATELAL LPPGSSLHQT GTVRAGSADD GTSVCDPDGR VWGFDNLYLA GNGVIPTAMA
ANVTLAGAVT AVRAARAVAE RSTASAAH
//
