ID A0A178AFD5_9PLEO Unreviewed; 794 AA.
AC A0A178AFD5;
DT 07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT 07-SEP-2016, sequence version 1.
DT 27-MAR-2024, entry version 38.
DE RecName: Full=asparagine--tRNA ligase {ECO:0000256|ARBA:ARBA00012816};
DE EC=6.1.1.22 {ECO:0000256|ARBA:ARBA00012816};
GN ORFNames=IQ06DRAFT_320591 {ECO:0000313|EMBL:OAK95217.1};
OS Stagonospora sp. SRC1lsM3a.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Dothideomycetes;
OC Pleosporomycetidae; Pleosporales; Massarineae; Massarinaceae; Stagonospora.
OX NCBI_TaxID=765868 {ECO:0000313|EMBL:OAK95217.1, ECO:0000313|Proteomes:UP000077206};
RN [1] {ECO:0000313|EMBL:OAK95217.1, ECO:0000313|Proteomes:UP000077206}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SRC1lsM3a {ECO:0000313|EMBL:OAK95217.1,
RC ECO:0000313|Proteomes:UP000077206};
RG DOE Joint Genome Institute;
RA Zeiner C.A., Purvine S.O., Zink E.M., Wu S., Pasa-Tolic L., Chaput D.L.,
RA Haridas S., Grigoriev I.V., Santelli C.M., Hansel C.M.;
RT "Comparative analysis of secretome profiles of manganese(II)-oxidizing
RT ascomycete fungi.";
RL Submitted (MAY-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the mitochondrial carrier (TC 2.A.29) family.
CC {ECO:0000256|ARBA:ARBA00006375}.
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DR EMBL; KV441723; OAK95217.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A178AFD5; -.
DR STRING; 765868.A0A178AFD5; -.
DR InParanoid; A0A178AFD5; -.
DR OrthoDB; 5481380at2759; -.
DR Proteomes; UP000077206; Unassembled WGS sequence.
DR GO; GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-KW.
DR GO; GO:0004816; F:asparagine-tRNA ligase activity; IEA:UniProtKB-EC.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0006421; P:asparaginyl-tRNA aminoacylation; IEA:InterPro.
DR GO; GO:0048250; P:iron import into the mitochondrion; IEA:UniProt.
DR CDD; cd04318; EcAsnRS_like_N; 1.
DR Gene3D; 1.50.40.10; Mitochondrial carrier domain; 1.
DR Gene3D; 2.40.50.140; Nucleic acid-binding proteins; 1.
DR InterPro; IPR004364; Aa-tRNA-synt_II.
DR InterPro; IPR006195; aa-tRNA-synth_II.
DR InterPro; IPR045864; aa-tRNA-synth_II/BPL/LPL.
DR InterPro; IPR004522; Asn-tRNA-ligase.
DR InterPro; IPR002312; Asp/Asn-tRNA-synth_IIb.
DR InterPro; IPR018108; Mitochondrial_sb/sol_carrier.
DR InterPro; IPR023395; Mt_carrier_dom_sf.
DR InterPro; IPR012340; NA-bd_OB-fold.
DR InterPro; IPR004365; NA-bd_OB_tRNA.
DR NCBIfam; TIGR00457; asnS; 1.
DR PANTHER; PTHR22594:SF34; ASPARAGINE--TRNA LIGASE, MITOCHONDRIAL-RELATED; 1.
DR PANTHER; PTHR22594; ASPARTYL/LYSYL-TRNA SYNTHETASE; 1.
DR Pfam; PF00153; Mito_carr; 3.
DR Pfam; PF00152; tRNA-synt_2; 1.
DR Pfam; PF01336; tRNA_anti-codon; 1.
DR PRINTS; PR01042; TRNASYNTHASP.
DR SUPFAM; SSF55681; Class II aaRS and biotin synthetases; 1.
DR SUPFAM; SSF103506; Mitochondrial carrier; 1.
DR SUPFAM; SSF50249; Nucleic acid-binding proteins; 1.
DR PROSITE; PS50862; AA_TRNA_LIGASE_II; 1.
DR PROSITE; PS50920; SOLCAR; 3.
PE 3: Inferred from homology;
KW Aminoacyl-tRNA synthetase {ECO:0000256|ARBA:ARBA00023146,
KW ECO:0000313|EMBL:OAK95217.1}; ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Ligase {ECO:0000256|ARBA:ARBA00022598};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|PROSITE-
KW ProRule:PRU00282}; Mitochondrion {ECO:0000256|ARBA:ARBA00023128};
KW Mitochondrion inner membrane {ECO:0000256|ARBA:ARBA00022792};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Protein biosynthesis {ECO:0000256|ARBA:ARBA00022917};
KW Reference proteome {ECO:0000313|Proteomes:UP000077206};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|PROSITE-
KW ProRule:PRU00282}; Transmembrane helix {ECO:0000256|ARBA:ARBA00022989}.
FT DOMAIN 178..523
FT /note="Aminoacyl-transfer RNA synthetases class-II family
FT profile"
FT /evidence="ECO:0000259|PROSITE:PS50862"
FT REPEAT 501..589
FT /note="Solcar"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00282"
FT REPEAT 600..684
FT /note="Solcar"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00282"
FT REPEAT 691..782
FT /note="Solcar"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00282"
SQ SEQUENCE 794 AA; 86506 MW; 4FB69C1C00FF02CF CRC64;
MLPIRRSACR FSLLRHNRFT TPASAQVSPS CRPRYNSTLC PDNIAELLRP SAAESKSVPP
LVTDGQTLKV NGYVRSVRKQ KRIAFAAIGD GSTLHTVQAV LSPELAEGLS TGVAVTVTGT
WTPSQGQGQS YELQVSDVQI LGENDAATSP IQKKYQTAEY LRTVPHLRPR LPFNALILRL
RSLVTAQITN YFANQNFVQC HPPIITSSDC EGAGEVFTVT PGAAVKSDSG SASSVKEHED
PFFGSPKYLT VSSQLHLEAL AQSVNKVWTL SPTFRAEKSD TARHLSEFYM LEAEMTFADD
LQTVMDVVEN MLRAVTEGIQ SSAVGQELLE ARARDHSTDA TSLSHDALAH RWQGLIHGPW
PRITYDTAIQ HLEDAVNNNN VEFEFAPKHA DGLQTEHERY IAESLGHGGP VFVTDYPRNI
KPFYMAPTKD AKTGGRTAST VACFDLLVPE ICELVGGSMR EHRLSELLKS MDEHGLRHTA
SAPSEDSEGS LQCYEALPPN FSLTANMLAG AFAGIAEHSV MYPVDLLKTR IQIINPSPGA
MYSGISNAMV TISRVEGFGT LWRGLSSVVM GAGPAHAVYF ASYEATKHAL GGNEGGSEEH
HPLAAAASGA AATISSDALM NPFDVIKQRM QMHGSIYKSV PHCAREVFRT EGIGAFYVSY
PTTLCMTVPF TALQFMAYES FSKVMNPTGR YDPYTHCFAG GIAGGFAAGF TTPLDVIKTL
LQTRGNATDA ELRNVSGLWQ AAKIIHQREG YRGYFRGLKP RIITTMPSTA ICWSAYEMAK
AFFIKRSTDP SKSI
//
