ID   A0A178EI82_9PLEO        Unreviewed;       719 AA.
AC   A0A178EI82;
DT   07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT   07-SEP-2016, sequence version 1.
DT   27-MAR-2024, entry version 28.
DE   SubName: Full=Zn-dependent exopeptidase {ECO:0000313|EMBL:OAL55737.1};
GN   ORFNames=IQ07DRAFT_583180 {ECO:0000313|EMBL:OAL55737.1};
OS   Pyrenochaeta sp. DS3sAY3a.
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Dothideomycetes;
OC   Pleosporomycetidae; Pleosporales; Pleosporineae; Cucurbitariaceae;
OC   Pyrenochaeta.
OX   NCBI_TaxID=765867 {ECO:0000313|EMBL:OAL55737.1, ECO:0000313|Proteomes:UP000077535};
RN   [1] {ECO:0000313|EMBL:OAL55737.1, ECO:0000313|Proteomes:UP000077535}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DS3sAY3a {ECO:0000313|EMBL:OAL55737.1,
RC   ECO:0000313|Proteomes:UP000077535};
RG   DOE Joint Genome Institute;
RA   Zeiner C.A., Purvine S.O., Zink E.M., Wu S., Pasa-Tolic L., Chaput D.L.,
RA   Haridas S., Grigoriev I.V., Santelli C.M., Hansel C.M.;
RT   "Comparative analysis of secretome profiles of manganese(II)-oxidizing
RT   ascomycete fungi.";
RL   Submitted (MAY-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the peptidase M28 family. M28B subfamily.
CC       {ECO:0000256|ARBA:ARBA00005634}.
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DR   EMBL; KV441637; OAL55737.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A178EI82; -.
DR   STRING; 765867.A0A178EI82; -.
DR   InParanoid; A0A178EI82; -.
DR   OrthoDB; 67337at2759; -.
DR   Proteomes; UP000077535; Unassembled WGS sequence.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   CDD; cd08022; M28_PSMA_like; 1.
DR   CDD; cd02121; PA_GCPII_like; 1.
DR   Gene3D; 3.50.30.30; -; 1.
DR   Gene3D; 1.20.930.40; Transferrin receptor-like, dimerisation domain; 1.
DR   Gene3D; 3.40.630.10; Zn peptidases; 1.
DR   InterPro; IPR046450; PA_dom_sf.
DR   InterPro; IPR003137; PA_domain.
DR   InterPro; IPR007484; Peptidase_M28.
DR   InterPro; IPR039373; Peptidase_M28B.
DR   InterPro; IPR007365; TFR-like_dimer_dom.
DR   InterPro; IPR036757; TFR-like_dimer_dom_sf.
DR   PANTHER; PTHR10404:SF46; GLUTAMATE CARBOXYPEPTIDASE 2 HOMOLOG; 1.
DR   PANTHER; PTHR10404; N-ACETYLATED-ALPHA-LINKED ACIDIC DIPEPTIDASE; 1.
DR   Pfam; PF02225; PA; 1.
DR   Pfam; PF04389; Peptidase_M28; 1.
DR   Pfam; PF04253; TFR_dimer; 1.
DR   SUPFAM; SSF52025; PA domain; 1.
DR   SUPFAM; SSF47672; Transferrin receptor-like dimerisation domain; 1.
DR   SUPFAM; SSF53187; Zn-dependent exopeptidases; 1.
PE   3: Inferred from homology;
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Reference proteome {ECO:0000313|Proteomes:UP000077535};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL          1..17
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           18..719
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5008085430"
FT   DOMAIN          161..234
FT                   /note="PA"
FT                   /evidence="ECO:0000259|Pfam:PF02225"
FT   DOMAIN          346..536
FT                   /note="Peptidase M28"
FT                   /evidence="ECO:0000259|Pfam:PF04389"
FT   DOMAIN          607..717
FT                   /note="Transferrin receptor-like dimerisation"
FT                   /evidence="ECO:0000259|Pfam:PF04253"
FT   REGION          216..277
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   719 AA;  78863 MW;  5031177F04832A21 CRC64;
     MATVWLLLLA LTQSSIACQR DLHLRDDIEH KQDLPLIPRQ LQPFPPQWSP NEKTLHTSIS
     TASIEAWSSY YTHGDHIAGR NKSMAEETAK QWTANGVPSS LVEYEVFLNY PKEQALILKR
     GNASIHQAQM YEDVLEEDET TGYPGAPPGF HGFSASGKVE AEYVYVGRGH KDDFAALKAA
     NVNLTGKIAL AKYGGPFRGV KVQNAEANGM IGVVIFTDPG DDGPQEAKGD APYPKGPARQ
     PSSIQRGSVA YINKYPGDPT TPGQPSKPGV KRVTPSNLPK IPSIPISYRD AIPILKALDG
     QGIPGKSINR GGWLGGLNAT YSTGPAPGVT LSLTNIMEET ITPIWNVIGI INGTNANETV
     IIGNHRDAWI IGGAADPNSG SAILVELTKA FGTLLKTGWK PRRNIIFASW DAEEYALVGS
     TEWVEDHAPW LSATAISYLN IDIGVSGPLP GSSSTPELRA LALATMQKTV YGARTLLDAW
     NALNQFRPED NGFGNLGSGS DYTAFMQLGI SSLDFGFDAD RSTPVYHYHS SYDSFAWMKS
     RIDTDFAIHA TAARFLALLT YRLADDALLP LDMADWARNV NYYVRDLVVA TMNLGGDYSE
     VQQQINITAL DEAAKRVRRV ADEWVERTGA EAFRRDEARV RRANGRMVEV LRLFVREGGL
     PGRPFYTNAL VAPNRDDGYK AHTLPASMET LEDKKFDECR QWNLWIAERL NRAAELLVV
//