ID A0A183EAH8_9BILA Unreviewed; 567 AA.
AC A0A183EAH8;
DT 07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT 07-SEP-2016, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE RecName: Full=RNA helicase {ECO:0000256|ARBA:ARBA00012552};
DE EC=3.6.4.13 {ECO:0000256|ARBA:ARBA00012552};
GN ORFNames=GPUH_LOCUS17969 {ECO:0000313|EMBL:VDN30793.1};
OS Gongylonema pulchrum.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Spirurina; Spiruromorpha; Spiruroidea; Gongylonematidae; Gongylonema.
OX NCBI_TaxID=637853 {ECO:0000313|Proteomes:UP000050760, ECO:0000313|WBParaSite:GPUH_0001799401-mRNA-1};
RN [1] {ECO:0000313|WBParaSite:GPUH_0001799401-mRNA-1}
RP IDENTIFICATION.
RG WormBaseParasite;
RL Submitted (JUN-2016) to UniProtKB.
RN [2] {ECO:0000313|EMBL:VDN30793.1, ECO:0000313|Proteomes:UP000271098}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG Pathogen Informatics;
RL Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; UYRT01085981; VDN30793.1; -; Genomic_DNA.
DR WBParaSite; GPUH_0001799401-mRNA-1; GPUH_0001799401-mRNA-1; GPUH_0001799401.
DR Proteomes; UP000050760; Unplaced.
DR Proteomes; UP000271098; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0003724; F:RNA helicase activity; IEA:UniProtKB-EC.
DR CDD; cd17946; DEADc_DDX24; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 3.
DR InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR014014; RNA_helicase_DEAD_Q_motif.
DR PANTHER; PTHR47959:SF13; ATP-DEPENDENT RNA HELICASE RHLE; 1.
DR PANTHER; PTHR47959; ATP-DEPENDENT RNA HELICASE RHLE-RELATED; 1.
DR Pfam; PF00270; DEAD; 2.
DR SMART; SM00487; DEXDc; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 3.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR PROSITE; PS51195; Q_MOTIF; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Helicase {ECO:0000256|ARBA:ARBA00022806};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000271098}.
FT DOMAIN 141..169
FT /note="DEAD-box RNA helicase Q"
FT /evidence="ECO:0000259|PROSITE:PS51195"
FT DOMAIN 233..474
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT REGION 39..99
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT MOTIF 141..169
FT /note="Q motif"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00552"
FT COMPBIAS 60..75
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 83..99
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 567 AA; 63178 MW; 73C6160FB3EEBB67 CRC64;
MPKVIAGCGE WRPVQITGDL VGDENLVFLS TVEECLPIEV DGSGGASRPK GKRTRKRKAE
KKDGLLADPR ELPRKKKRPK KERKDEVHAS PEHPEECQNS KEIWETAQDG CVYAPNAFHA
LKYNGPWRGE LAEAGANAAR TQWTALDISD EVLQAVADMG FTEPTEIQRL VIPSAVRDRL
DIIGCAETVN FDSPNQQKFN DLSFRALSEI DLISLDARKR FTEPTEIQRL VIPSAVRDRL
DIIGCAETGS GKTLAFAVPI IEYLLAAKRS SMDGNEQQRT IRALILAPTR ELVVQIKKHI
HALLKYTPFK VASIVGGLSL QKQERILKYV PEIVVATPGR LLALMSSAES IKCLSSCFGY
LKVASIVGGL SLQKQERILK YVPEIVVATP GRLLALMSSA ESIKCLSSWS ELQCLVVDET
DRMIEKGHFE DLQQILAAIR KTTSQKLQTF VFSATLTYIH PATKKKHRER STNMTVEEKI
RRLIEVTGIR RGKNKVIDIS GERGTAETIV ESRINCKNLL EKDTALVYLL KRYSGRTLVF
TNSVDASRRL HGILTQVPFL ISTQSIT
//
