ID A0A183HZQ1_9BILA Unreviewed; 409 AA.
AC A0A183HZQ1;
DT 07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT 07-SEP-2016, sequence version 1.
DT 24-JAN-2024, entry version 24.
DE RecName: Full=protein-L-isoaspartate(D-aspartate) O-methyltransferase {ECO:0000256|ARBA:ARBA00011890};
DE EC=2.1.1.77 {ECO:0000256|ARBA:ARBA00011890};
GN ORFNames=OFLC_LOCUS12963 {ECO:0000313|EMBL:VDP12600.1};
OS Onchocerca flexuosa.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Spirurina; Spiruromorpha; Filarioidea; Onchocercidae; Onchocerca.
OX NCBI_TaxID=387005 {ECO:0000313|Proteomes:UP000050787, ECO:0000313|WBParaSite:OFLC_0001296401-mRNA-1};
RN [1] {ECO:0000313|WBParaSite:OFLC_0001296401-mRNA-1}
RP IDENTIFICATION.
RG WormBaseParasite;
RL Submitted (JUN-2016) to UniProtKB.
RN [2] {ECO:0000313|EMBL:VDP12600.1, ECO:0000313|Proteomes:UP000267606}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG Pathogen Informatics;
RL Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the methyltransferase superfamily. L-
CC isoaspartyl/D-aspartyl protein methyltransferase family.
CC {ECO:0000256|ARBA:ARBA00005369}.
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DR EMBL; UZAJ01039993; VDP12600.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A183HZQ1; -.
DR STRING; 387005.A0A183HZQ1; -.
DR WBParaSite; OFLC_0001296401-mRNA-1; OFLC_0001296401-mRNA-1; OFLC_0001296401.
DR Proteomes; UP000050787; Unplaced.
DR Proteomes; UP000267606; Unassembled WGS sequence.
DR GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR GO; GO:0004719; F:protein-L-isoaspartate (D-aspartate) O-methyltransferase activity; IEA:InterPro.
DR GO; GO:0036211; P:protein modification process; IEA:InterPro.
DR CDD; cd02440; AdoMet_MTases; 1.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 2.
DR InterPro; IPR002048; EF_hand_dom.
DR InterPro; IPR000682; PCMT.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR NCBIfam; TIGR00080; pimt; 1.
DR PANTHER; PTHR11579; PROTEIN-L-ISOASPARTATE O-METHYLTRANSFERASE; 1.
DR PANTHER; PTHR11579:SF0; PROTEIN-L-ISOASPARTATE(D-ASPARTATE) O-METHYLTRANSFERASE; 1.
DR Pfam; PF01135; PCMT; 2.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 2.
DR PROSITE; PS50222; EF_HAND_2; 1.
DR PROSITE; PS01279; PCMT; 1.
PE 3: Inferred from homology;
FT DOMAIN 365..400
FT /note="EF-hand"
FT /evidence="ECO:0000259|PROSITE:PS50222"
SQ SEQUENCE 409 AA; 44735 MW; FD1B6AE2F5D6ACAA CRC64;
MSFPQNVSNS MLVNFLKKLS CDLVLQLLIF IETGNIKDER VEKVMLSVDR ADFCPRNSYQ
DFPQQIGYNA TISAPHMHAL ALELLKDHLS EGSKALDIGS GSGYLTVCMA LMVGRRGRVI
GIDHIKELVD LSINNINKHH SDLLMDGRLK MVTGDGRSGH KADAPYAAIH VGAAAQKLPD
IKNMAWRSHG DSNASLVENL RRNGLFRDER VKMTMLRVDR ADFCPRNPYL DNPEPIGSNA
TISAPHMHAA ALERLKDHLT EGDKALDIGS GSGYLTTCMA YMVGATGKVV GVEHIRQLVD
LSISNIKKNH ASLLEGRILI VEGDGRRGFP QYAPYNAIHV GAAAPNVPDE LLNQLAPGGR
MLIPVGAAHA DQRFLQIDKD GKGKVTVNDL MGVVYVPLTN KENQIGRNQ
//
