ID A0A183I2C5_9BILA Unreviewed; 1218 AA.
AC A0A183I2C5;
DT 07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT 07-SEP-2016, sequence version 1.
DT 27-MAR-2024, entry version 33.
DE SubName: Full=Myosin motor domain-containing protein {ECO:0000313|WBParaSite:OFLC_0001388801-mRNA-1};
GN ORFNames=OFLC_LOCUS13887 {ECO:0000313|EMBL:VDP14901.1};
OS Onchocerca flexuosa.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Spirurina; Spiruromorpha; Filarioidea; Onchocercidae; Onchocerca.
OX NCBI_TaxID=387005 {ECO:0000313|Proteomes:UP000050787, ECO:0000313|WBParaSite:OFLC_0001388801-mRNA-1};
RN [1] {ECO:0000313|WBParaSite:OFLC_0001388801-mRNA-1}
RP IDENTIFICATION.
RG WormBaseParasite;
RL Submitted (JUN-2016) to UniProtKB.
RN [2] {ECO:0000313|EMBL:VDP14901.1, ECO:0000313|Proteomes:UP000267606}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG Pathogen Informatics;
RL Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the TRAFAC class myosin-kinesin ATPase
CC superfamily. Myosin family. {ECO:0000256|ARBA:ARBA00008314,
CC ECO:0000256|PROSITE-ProRule:PRU00782}.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00782}.
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DR EMBL; UZAJ01040450; VDP14901.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A183I2C5; -.
DR STRING; 387005.A0A183I2C5; -.
DR WBParaSite; OFLC_0001388801-mRNA-1; OFLC_0001388801-mRNA-1; OFLC_0001388801.
DR Proteomes; UP000050787; Unplaced.
DR Proteomes; UP000267606; Unassembled WGS sequence.
DR GO; GO:0016459; C:myosin complex; IEA:UniProtKB-KW.
DR GO; GO:0032982; C:myosin filament; IEA:UniProtKB-KW.
DR GO; GO:0030017; C:sarcomere; IEA:UniProt.
DR GO; GO:0003779; F:actin binding; IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0003774; F:cytoskeletal motor activity; IEA:InterPro.
DR Gene3D; 1.20.5.340; -; 2.
DR Gene3D; 1.20.5.4820; -; 1.
DR Gene3D; 1.20.58.530; -; 1.
DR Gene3D; 3.40.850.10; Kinesin motor domain; 1.
DR InterPro; IPR000048; IQ_motif_EF-hand-BS.
DR InterPro; IPR036961; Kinesin_motor_dom_sf.
DR InterPro; IPR001609; Myosin_head_motor_dom.
DR InterPro; IPR002928; Myosin_tail.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR45615; MYOSIN HEAVY CHAIN, NON-MUSCLE; 1.
DR PANTHER; PTHR45615:SF71; MYOSIN HEAVY CHAIN, NON-MUSCLE; 1.
DR Pfam; PF00063; Myosin_head; 1.
DR Pfam; PF01576; Myosin_tail_1; 1.
DR SMART; SM00242; MYSc; 1.
DR SUPFAM; SSF90257; Myosin rod fragments; 4.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS50096; IQ; 1.
DR PROSITE; PS51456; MYOSIN_MOTOR; 1.
PE 3: Inferred from homology;
KW Actin-binding {ECO:0000256|PROSITE-ProRule:PRU00782};
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Motor protein {ECO:0000256|ARBA:ARBA00023175};
KW Muscle protein {ECO:0000256|ARBA:ARBA00023179};
KW Myosin {ECO:0000256|ARBA:ARBA00023123, ECO:0000256|PROSITE-
KW ProRule:PRU00782}; Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Thick filament {ECO:0000256|ARBA:ARBA00022433}.
FT DOMAIN 1..135
FT /note="Myosin motor"
FT /evidence="ECO:0000259|PROSITE:PS51456"
FT REGION 13..35
FT /note="Actin-binding"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00782"
FT REGION 1123..1159
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1126..1149
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1218 AA; 143436 MW; 581D42992BF9A6AF CRC64;
MFRTVSQMHK EQLTRLMTTL RNTNPHFVRC IIPNHEKKAG KISSLLVLEQ LRCNGVLEGI
RICRQGFPNR VLFQEFRHRY EILTPNIIPK GFMDGKEAVR KMIDGLEMEN NLYRIGQSKI
FFRTGVLAHL EEERDLKLTG LIVSFQAQCR AFLARRLYQK RMQQSNAIRV LQRNGLAWLK
LRNWQWWRLF TKVKPLLQVT NQEAAIALKD EELKVVKDKL SKKEIEYGDI EKRLKQLSEE
RNVLQEQLQQ ESEERAEVEE MRERLSSKKV ELEDMLTELN SKLDEGEEQV EKLTEEKKKL
QETVRDLEEQ LEEEEQARQK LMLDKVSVDQ RWKKLEEKHA ELVDSYEKLV KEKKNIEERA
AQLTNHLLEE EERAKHVGKQ RSRIEMQLQE QEQELKKEKQ MRTEVERLKR KLEIELEEQK
ELLEEKRNKL EELNSLLSKR EEELTTLLTK SDEDSANNVI LQKQIRELES ALEELKEDLD
NEKVLREKAE KIRRDLNDDL ETLRTEYLEA ADKTAISLEI QKKKDEELKE LKRALESANA
AGDVKAEELK QKYQKQVEEL VEQVEQQKRL RSQVEKTKNS LDIEKSSLAA ELIVVQAAKA
EADKKRKQAE TACIELNARI AELDSAKSAL AQHLAKAQSE LDSVVKQKED DEQNVSALQR
KITLLEQQLA EAQDQLQEET RSKLAMQTRV RQLEDDLIES LEMREEVELK RKELEGQLDS
VRVALADAKK KADEGVLQQM EEMKKKAQRD LEVTQKTLAE MEVARDRFER SKRKLQQEVE
DANIELNNVR TYSRDLEKKQ RRFDQQLAEE RANLQKVVNE RDALAQESRD RETRILSLNN
DLESLRSQLE ESERVKRMLQ MELDESVSSK DDVGKNVHEL EKAKRQLEAE LQEQRAQVEE
LEDAVQIAED ARLRLDVNLQ ALKSEQERML AAKEQESEEK RRSLLKQIRD LENELENERR
TRTGAVSNRK KIESQLMEME QQLELANRLK DDYSRQFKKY QQIIKDMQHD SEEVRQSKEE
LANSLREMER KLRTLDAENT RLLEANESLM NQKRQLEAEK DELEDARSRG GGMNVDERRR
LEAKVAALEE EVEEEQSLAE LALDKQRKAQ MQVEQLTTEL SVERSTTQKL ETEKQAMERA
NRELKNKVSE LETSAQTRSR AQIAALEAKI QYLEEQYNAE SQERANATRQ YRRIEKRLAD
AILQLEDERR NTEQNKEQ
//
