ID A0A183LRI6_9TREM Unreviewed; 1067 AA.
AC A0A183LRI6;
DT 07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT 07-SEP-2016, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=ANF_receptor domain-containing protein {ECO:0000313|WBParaSite:SMRZ_0000641201-mRNA-1};
GN ORFNames=SMRZ_LOCUS6411 {ECO:0000313|EMBL:VDO70959.1};
OS Schistosoma margrebowiei.
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Platyhelminthes; Trematoda;
OC Digenea; Strigeidida; Schistosomatoidea; Schistosomatidae; Schistosoma.
OX NCBI_TaxID=48269 {ECO:0000313|WBParaSite:SMRZ_0000641201-mRNA-1};
RN [1] {ECO:0000313|WBParaSite:SMRZ_0000641201-mRNA-1}
RP IDENTIFICATION.
RG WormBaseParasite;
RL Submitted (JUN-2016) to UniProtKB.
RN [2] {ECO:0000313|EMBL:VDO70959.1, ECO:0000313|Proteomes:UP000277204}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Zambia {ECO:0000313|EMBL:VDO70959.1,
RC ECO:0000313|Proteomes:UP000277204};
RG Pathogen Informatics;
RL Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; UZAI01002382; VDO70959.1; -; Genomic_DNA.
DR STRING; 48269.A0A183LRI6; -.
DR WBParaSite; SMRZ_0000641201-mRNA-1; SMRZ_0000641201-mRNA-1; SMRZ_0000641201.
DR Proteomes; UP000277204; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0004965; F:G protein-coupled GABA receptor activity; IEA:InterPro.
DR Gene3D; 3.40.50.2300; -; 4.
DR InterPro; IPR001828; ANF_lig-bd_rcpt.
DR InterPro; IPR002455; GPCR3_GABA-B.
DR InterPro; IPR028082; Peripla_BP_I.
DR PANTHER; PTHR10519; GABA-B RECEPTOR; 1.
DR PANTHER; PTHR10519:SF20; GAMMA-AMINOBUTYRIC ACID TYPE B RECEPTOR SUBUNIT 2; 1.
DR Pfam; PF01094; ANF_receptor; 1.
DR SUPFAM; SSF53822; Periplasmic binding protein-like I; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000277204};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 584..608
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 62..187
FT /note="Receptor ligand binding region"
FT /evidence="ECO:0000259|Pfam:PF01094"
FT REGION 283..302
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 323..343
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 323..340
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1067 AA; 122050 MW; 47D1E8BE9B63D445 CRC64;
ALLDSHIDRQ STYKQVACRW LRQNPTKWKS WTVDWDKKLN LTVAGLFSMY GKWVLYGLDR
VAQEAMNFVN ADSDYFRNSE YALSLDVRNL TCEPDVVLSD YFKVLENAVN TRLIGSIAAL
CSDSIEAVVE LANIRKQIIV SPTVGSARFL EQQQYHYFFR TVPSMTLANF ILLRLFLVWG
WHRIVTLEEL KQQNSRIFVV EYDARGTYLI LCAAYHEGMY FSAGYVWFLN PWLSDQWWSE
LVSRNTECNF SEMLNITSWT FTVGHQLLIG PMVHSFIPRT SEFMDSDSKS GNNSSGTPNR
TSFEQIRRRR NVFVQSQTFE VPPVLSRTKH NPNPNDFGKS TFSDHSKRKL IKDPLHDYTV
YTYDAVILLA SAVVHLLREN PAAASALNHP DVSETLRTLV ARTNFGYRFQ TDNSTTGQSS
EINELVPGIN DDNFGVDAGF QLAGDYYGIR SQSPASASNL RFNDHNERIA DYWLLKQRHL
NTTVPIIMWS TKNYEEVHEQ DQQQQSYDPF NHMISSNNMS NKYDWKTTNA PFLYDEFQKR
MTERWLDHVN WHTLGGPPND GSINEKNCTL SFLSNQLHMG CTGATVFVTV TVTVLVLLPL
IIFAHFYYRR KLKEIENRTR KPFEELCTEL ADLDVSYGLL CELINHCCKH QWQHRPSSMN
QVLEVLIAYP DCIRPFLTDD PPKPNTTIDS LPFQPTVDTC IISESAMTGL AAIDSVGGFR
TIRSASTVVV PISSCSPSPV PLNLPDGNSD KYYGSEKRLS EQTNLRDNTL SNHHTIFDWS
DNYTSHPYTD SSVHSKLIEF YQLPMFSDRQ TLFPPVVTDE SKEPNIMSKS GESSSLPPVF
DNYTTSFVTS IPNAINTSNV LFNLSTSPIS TTPSYQSIDE TSQLIMKSPE LITDQYTYST
GNTLHIRKQK RSNTTLINNA TSNILDEFDN LLSDNQLKLS LDADSIMHIE ESDRSHMWIS
EDKNSDKQFF IIPRNKFHMF NVSSVPRNPI QTRNINRLRP TRSLINLTSV RYPKHYLQNN
IESNHCASVD HFSSFTKQSD IHSPDLILPP SLFTFISDSF ISGRKTV
//
