ID A0A183N086_9TREM Unreviewed; 431 AA.
AC A0A183N086;
DT 07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT 07-SEP-2016, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE SubName: Full=Ras-GEF domain-containing protein {ECO:0000313|WBParaSite:SMRZ_0002171201-mRNA-1};
GN ORFNames=SMRZ_LOCUS21711 {ECO:0000313|EMBL:VDP40491.1};
OS Schistosoma margrebowiei.
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Platyhelminthes; Trematoda;
OC Digenea; Strigeidida; Schistosomatoidea; Schistosomatidae; Schistosoma.
OX NCBI_TaxID=48269 {ECO:0000313|WBParaSite:SMRZ_0002171201-mRNA-1};
RN [1] {ECO:0000313|WBParaSite:SMRZ_0002171201-mRNA-1}
RP IDENTIFICATION.
RG WormBaseParasite;
RL Submitted (JUN-2016) to UniProtKB.
RN [2] {ECO:0000313|EMBL:VDP40491.1, ECO:0000313|Proteomes:UP000277204}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Zambia {ECO:0000313|EMBL:VDP40491.1,
RC ECO:0000313|Proteomes:UP000277204};
RG Pathogen Informatics;
RL Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; UZAI01018829; VDP40491.1; -; Genomic_DNA.
DR STRING; 48269.A0A183N086; -.
DR WBParaSite; SMRZ_0002171201-mRNA-1; SMRZ_0002171201-mRNA-1; SMRZ_0002171201.
DR Proteomes; UP000277204; Unassembled WGS sequence.
DR GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:UniProtKB-KW.
DR GO; GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
DR Gene3D; 1.10.840.10; Ras guanine-nucleotide exchange factors catalytic domain; 1.
DR InterPro; IPR008937; Ras-like_GEF.
DR InterPro; IPR023578; Ras_GEF_dom_sf.
DR InterPro; IPR001895; RASGEF_cat_dom.
DR InterPro; IPR036964; RASGEF_cat_dom_sf.
DR PANTHER; PTHR23113; GUANINE NUCLEOTIDE EXCHANGE FACTOR; 1.
DR PANTHER; PTHR23113:SF368; RAS-GEF DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF00617; RasGEF; 1.
DR SMART; SM00147; RasGEF; 1.
DR SUPFAM; SSF48366; Ras GEF; 1.
DR PROSITE; PS50009; RASGEF_CAT; 1.
PE 4: Predicted;
KW Guanine-nucleotide releasing factor {ECO:0000256|ARBA:ARBA00022658,
KW ECO:0000256|PROSITE-ProRule:PRU00168};
KW Reference proteome {ECO:0000313|Proteomes:UP000277204}.
FT DOMAIN 1..231
FT /note="Ras-GEF"
FT /evidence="ECO:0000259|PROSITE:PS50009"
FT REGION 300..320
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 431 AA; 49395 MW; 49273831C80ABD92 CRC64;
MVAVVVSSGV SLEFYTLKWN SKEKLQYAPN IVASTRWFNQ IIFWVHKDIL NEKSLSKRTE
ILSHFIRIAK KLVDLNNFSS GMAIVSALHM QCIHRLNATW SNLSSRDRHT FRKLSDLFSQ
EENFINLRSA VDNSRLPCIP YLGVYLSDLT FIDVAASSSY SRRENSTWTN QGKQDRINNI
LRIIANFQQS NYPFVRNESI ASYLEAQRYI EELQRFIEDA NYKLSIQLEP PPTSSPPDLS
CQNTVPPNYS FLSNNDNILK PVPIYNCTTN ITSNCDTITT TTTTLSSIKT TTLSLSCKTK
NNKTTGTRHT NKGNPSNSTV NQLEKQIKSN SSLYDLLEPP IIPPPPRVKQ TYSQEDISIP
SNIHCLTSNH SVVNSIQRPR KRPTHRKLGS WGVRKCEHSK KGYNTRLRNM NNNNNNNRFS
EYNKMIKRFL S
//
