ID A0A183P1K0_9TREM Unreviewed; 422 AA.
AC A0A183P1K0;
DT 07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT 07-SEP-2016, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE RecName: Full=beta-N-acetylhexosaminidase {ECO:0000256|ARBA:ARBA00012663};
DE EC=3.2.1.52 {ECO:0000256|ARBA:ARBA00012663};
GN ORFNames=SMTD_LOCUS8236 {ECO:0000313|EMBL:VDP43662.1};
OS Schistosoma mattheei.
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Platyhelminthes; Trematoda;
OC Digenea; Strigeidida; Schistosomatoidea; Schistosomatidae; Schistosoma.
OX NCBI_TaxID=31246 {ECO:0000313|WBParaSite:SMTD_0000823501-mRNA-1};
RN [1] {ECO:0000313|WBParaSite:SMTD_0000823501-mRNA-1}
RP IDENTIFICATION.
RG WormBaseParasite;
RL Submitted (JUN-2016) to UniProtKB.
RN [2] {ECO:0000313|EMBL:VDP43662.1, ECO:0000313|Proteomes:UP000269396}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Denwood {ECO:0000313|EMBL:VDP43662.1}, and Denwood, Zambia
RC {ECO:0000313|Proteomes:UP000269396};
RG Pathogen Informatics;
RL Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=Hydrolysis of terminal non-reducing N-acetyl-D-hexosamine
CC residues in N-acetyl-beta-D-hexosaminides.; EC=3.2.1.52;
CC Evidence={ECO:0000256|ARBA:ARBA00001231};
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 20 family.
CC {ECO:0000256|ARBA:ARBA00006285}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; UZAL01028781; VDP43662.1; -; Genomic_DNA.
DR STRING; 31246.A0A183P1K0; -.
DR WBParaSite; SMTD_0000823501-mRNA-1; SMTD_0000823501-mRNA-1; SMTD_0000823501.
DR Proteomes; UP000269396; Unassembled WGS sequence.
DR GO; GO:0004563; F:beta-N-acetylhexosaminidase activity; IEA:UniProtKB-EC.
DR GO; GO:0102148; F:N-acetyl-beta-D-galactosaminidase activity; IEA:UniProtKB-EC.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR Gene3D; 3.20.20.80; Glycosidases; 1.
DR InterPro; IPR025705; Beta_hexosaminidase_sua/sub.
DR InterPro; IPR015883; Glyco_hydro_20_cat.
DR InterPro; IPR017853; Glycoside_hydrolase_SF.
DR PANTHER; PTHR22600; BETA-HEXOSAMINIDASE; 1.
DR PANTHER; PTHR22600:SF21; BETA-HEXOSAMINIDASE A; 1.
DR Pfam; PF00728; Glyco_hydro_20; 1.
DR PRINTS; PR00738; GLHYDRLASE20.
DR SUPFAM; SSF51445; (Trans)glycosidases; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Reference proteome {ECO:0000313|Proteomes:UP000269396}.
FT DOMAIN 1..228
FT /note="Glycoside hydrolase family 20 catalytic"
FT /evidence="ECO:0000259|Pfam:PF00728"
FT ACT_SITE 62
FT /note="Proton donor"
FT /evidence="ECO:0000256|PIRSR:PIRSR625705-1"
SQ SEQUENCE 422 AA; 47461 MW; 1FC7C8229365CF37 CRC64;
HANSWGKGYP EILTKCYIKG EPDGTLGPIN PINNISYNFM SQLYKELFSV FPDNWFHLGG
DEVEYNCWHS NPSIIEFMKR MKFGDDYHRL EGYYINNLIQ IINDVKPPGR NITPVVWQEI
FENGFRGDKS TVIHVWKDLY WESVVKNATK TGYRVLFSAA WYLNYISYGD DWRYHYHVDP
RDFGGSKDDA KLVIGGEAAM WGEYVDDTNL FSRSWPRGSA VAERLWTHGS PNATDFIPRV
EELRCRMLSC KSAALALPIR TFTSASDPPC SSKHFIFFES PSSAIRLLLL PLCILRPTAA
EAAATLVVFS CSCCCDCDRM ARSSAKSRSS SWILDVHCIP CFYPDVDVFS IQSITRRRMW
SILAVTATSA FSASDGMLSS PATLPLLICL TAIMISSIVG RPTSIRRSVC ATSMLDGFHA
AG
//
