ID   A0A183QP83_9TREM        Unreviewed;       326 AA.
AC   A0A183QP83;
DT   07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT   07-SEP-2016, sequence version 1.
DT   27-MAR-2024, entry version 26.
DE   SubName: Full=Integrin_alpha2 domain-containing protein {ECO:0000313|WBParaSite:SROB_0000547101-mRNA-1};
OS   Schistosoma rodhaini.
OC   Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Platyhelminthes; Trematoda;
OC   Digenea; Strigeidida; Schistosomatoidea; Schistosomatidae; Schistosoma.
OX   NCBI_TaxID=6188 {ECO:0000313|WBParaSite:SROB_0000547101-mRNA-1};
RN   [1] {ECO:0000313|WBParaSite:SROB_0000547101-mRNA-1}
RP   IDENTIFICATION.
RG   WormBaseParasite;
RL   Submitted (JUN-2016) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004479}; Single-
CC       pass type I membrane protein {ECO:0000256|ARBA:ARBA00004479}.
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DR   AlphaFoldDB; A0A183QP83; -.
DR   STRING; 6188.A0A183QP83; -.
DR   WBParaSite; SROB_0000547101-mRNA-1; SROB_0000547101-mRNA-1; SROB_0000547101.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0007229; P:integrin-mediated signaling pathway; IEA:UniProtKB-KW.
DR   Gene3D; 1.20.5.930; Bicelle-embedded integrin alpha(iib) transmembrane segment; 1.
DR   Gene3D; 2.60.40.1530; ntegrin, alpha v. Chain A, domain 4; 1.
DR   InterPro; IPR018184; Integrin_alpha_C_CS.
DR   InterPro; IPR048286; Integrin_alpha_Ig-like_3.
DR   InterPro; IPR032695; Integrin_dom_sf.
DR   PANTHER; PTHR23220; INTEGRIN ALPHA; 1.
DR   PANTHER; PTHR23220:SF133; INTEGRIN ALPHA-PS2; 1.
DR   Pfam; PF20806; Integrin_A_Ig_3; 1.
DR   SUPFAM; SSF69179; Integrin domains; 1.
DR   PROSITE; PS00242; INTEGRIN_ALPHA; 1.
PE   4: Predicted;
KW   Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW   Integrin {ECO:0000256|ARBA:ARBA00023037};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        215..242
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          12..196
FT                   /note="Integrin alpha third immunoglobulin-like"
FT                   /evidence="ECO:0000259|Pfam:PF20806"
FT   REGION          253..326
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        259..287
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        297..326
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   326 AA;  37336 MW;  2AACA2B5C8FFADF0 CRC64;
     MSAENQIGDV RIVGKFTVRN LRKHSLIPAS RLIIDWPFEF SGLINEPHGK YLLYLLENPY
     VIQHALPIPG QTGDNGTSVV CDSQALQKVV NPHNFRIFSR LRKSNDGVPV RTAPINIPSE
     NLSRYPPLSD KMILESVPDR LTDSKKLVDR KMTTISCYNG RIRCVPIVCD LGKLSYKAGP
     ITLEFIARLW ENTMREIEVH IFNNLEQKPI PPKYMALYIG LAVFGGLLLL SILVIILYKA
     GFFKRKRFMR RRTKVPPTEP TQRLGQYTST EPKQRQPLVS PIQTSYHDDR KISSRRTNYH
     PVPNTQEPAY RRTPYSPSSD FPISHK
//