ID   A0A183S4A8_9TREM        Unreviewed;       430 AA.
AC   A0A183S4A8;
DT   07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT   07-SEP-2016, sequence version 1.
DT   27-MAR-2024, entry version 25.
DE   RecName: Full=Neurotransmitter-gated ion-channel transmembrane domain-containing protein {ECO:0000259|Pfam:PF02932};
OS   Schistosoma rodhaini.
OC   Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Platyhelminthes; Trematoda;
OC   Digenea; Strigeidida; Schistosomatoidea; Schistosomatidae; Schistosoma.
OX   NCBI_TaxID=6188 {ECO:0000313|WBParaSite:SROB_0002314101-mRNA-1};
RN   [1] {ECO:0000313|WBParaSite:SROB_0002314101-mRNA-1}
RP   IDENTIFICATION.
RG   WormBaseParasite;
RL   Submitted (JUN-2016) to UniProtKB.
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DR   AlphaFoldDB; A0A183S4A8; -.
DR   STRING; 6188.A0A183S4A8; -.
DR   WBParaSite; SROB_0002314101-mRNA-1; SROB_0002314101-mRNA-1; SROB_0002314101.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0006811; P:monoatomic ion transport; IEA:InterPro.
DR   Gene3D; 1.20.58.390; Neurotransmitter-gated ion-channel transmembrane domain; 1.
DR   InterPro; IPR036719; Neuro-gated_channel_TM_sf.
DR   InterPro; IPR038050; Neuro_actylchol_rec.
DR   InterPro; IPR006029; Neurotrans-gated_channel_TM.
DR   Pfam; PF02932; Neur_chan_memb; 1.
DR   SUPFAM; SSF90112; Neurotransmitter-gated ion-channel transmembrane pore; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        402..419
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          293..419
FT                   /note="Neurotransmitter-gated ion-channel transmembrane"
FT                   /evidence="ECO:0000259|Pfam:PF02932"
FT   REGION          205..231
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          265..327
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        297..311
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        312..326
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   430 AA;  48972 MW;  5A9CD0A125A4B0A7 CRC64;
     MCTSLSGYPD IYKSSIHSIF ANVLDQNAYN WRLHILLFRI NFDSTFVFLS NYLDNAKVNR
     FGKPHGNKFC SPEFCYANSR QAHMRSQFST GSPNHKFPGC YYPDNEAEMK HFSQFSRRQT
     QETEQATPCS FCPACAGLAA AAVASGRGSN DIDPSYHAEK QYSMQTTPKN HFPHDPTDEL
     ATVWAAAIND SNICNKRLSS RALIENNKQS EDEEETTDDE DHEPHLMRNK NIGPDLEHFL
     LQCIKPGASK KALSAANAKW NSPLQNTQLT SPLYPFTSPI CQDDSEDDER SKMNLPRWSS
     AGHSIGNRSH RGLNHNSDKE INHDPDNNNL WRANSSSFIS RKFKKSANNS DQRLLKRVHM
     VTRDVSEIVK GIRFMQKQNE KKEKNNKIIS EWRAVGMVLD RLFFIIYLCA LGISILLYFP
     RSGEDSEETI
//