ID A0A183VWX5_TRIRE Unreviewed; 611 AA.
AC A0A183VWX5;
DT 07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT 07-SEP-2016, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE SubName: Full=XPGI domain-containing protein {ECO:0000313|WBParaSite:TRE_0000498501-mRNA-1};
GN ORFNames=TRE_LOCUS4980 {ECO:0000313|EMBL:VDQ00860.1};
OS Trichobilharzia regenti (Nasal bird schistosome).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Platyhelminthes; Trematoda;
OC Digenea; Strigeidida; Schistosomatoidea; Schistosomatidae; Trichobilharzia.
OX NCBI_TaxID=157069 {ECO:0000313|WBParaSite:TRE_0000498501-mRNA-1};
RN [1] {ECO:0000313|WBParaSite:TRE_0000498501-mRNA-1}
RP IDENTIFICATION.
RG WormBaseParasite;
RL Submitted (JUN-2016) to UniProtKB.
RN [2] {ECO:0000313|EMBL:VDQ00860.1, ECO:0000313|Proteomes:UP000280995}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG Pathogen Informatics;
RL Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR EMBL; UZAO01053673; VDQ00860.1; -; Genomic_DNA.
DR STRING; 157069.A0A183VWX5; -.
DR WBParaSite; TRE_0000498501-mRNA-1; TRE_0000498501-mRNA-1; TRE_0000498501.
DR Proteomes; UP000280995; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0004519; F:endonuclease activity; IEA:UniProtKB-KW.
DR GO; GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
DR Gene3D; 1.10.150.20; 5' to 3' exonuclease, C-terminal subdomain; 1.
DR Gene3D; 3.40.50.1010; 5'-nuclease; 1.
DR InterPro; IPR036279; 5-3_exonuclease_C_sf.
DR InterPro; IPR008918; HhH2.
DR InterPro; IPR029060; PIN-like_dom_sf.
DR InterPro; IPR006086; XPG-I_dom.
DR InterPro; IPR006084; XPG/Rad2.
DR PANTHER; PTHR16171:SF7; DNA EXCISION REPAIR PROTEIN ERCC-5; 1.
DR PANTHER; PTHR16171; DNA REPAIR PROTEIN COMPLEMENTING XP-G CELLS-RELATED; 1.
DR Pfam; PF00867; XPG_I; 1.
DR PRINTS; PR00853; XPGRADSUPER.
DR SMART; SM00279; HhH2; 1.
DR SMART; SM00484; XPGI; 1.
DR SUPFAM; SSF47807; 5' to 3' exonuclease, C-terminal subdomain; 1.
DR SUPFAM; SSF88723; PIN domain-like; 1.
PE 4: Predicted;
KW DNA damage {ECO:0000256|ARBA:ARBA00022763};
KW DNA repair {ECO:0000256|ARBA:ARBA00023204};
KW Endonuclease {ECO:0000256|ARBA:ARBA00022759};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022759};
KW Nuclease {ECO:0000256|ARBA:ARBA00022759};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000280995}.
FT DOMAIN 464..539
FT /note="XPG-I"
FT /evidence="ECO:0000259|SMART:SM00484"
FT REGION 381..412
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 386..412
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 611 AA; 68983 MW; 3519020A4E7E2EE8 CRC64;
MDLNSDAFCS LPLPAQLRVV QLAREILDTS SCRRDLIQRN NEASFDPETF SDVQTKRLLL
RRRLAERQQE LSDNLTKQEA VQQVLQLDNS MIKNILKNQS LCSALSTEST ETIATAMRIQ
SQDVGHAILL KQSPLKKSNS LSKLPSSTTF DLEKLIALNP IELNASINNE EVECTKEASS
LDASLDDTKD LKKVSNVELP SNDVCSPKQL QIPVNEQNII EESITDSKCY SFDEQSTISE
SLNKKQMEDE SEKEANISDN FNKVDQTIII NNNNSSENVL VVSASQDSFS LETEKLPIKP
ESPVFESLLC DHNNIRRDES NLNSNLSQQI HEVDDVKDFE DTQQNNEMNS DEDDDDDDFI
EVETHEHVDL SNISSESTIL QKYSTDKSSS HEESESTYTH EESESFDKET VEDSNIKEYI
SSSDLEDDDL IVDDNMLREK ADRLTRQAQS TTTRCISEAQ DLLRLFGFPF VVSPEEAEAQ
CVALQRYGLV DLVASDDSDV WPFGVRLVCR HLFGTGDDKK RRTNPSLYKL DEVKRKLGLT
VENILRLTLL CGSDYTHGID QVGPVTAIEI LSEFGEVDDS LNTEMNNWLH GKCKPSEELL
QNILKPLEQF T
//
