ID A0A194Q2X3_PAPXU Unreviewed; 1922 AA.
AC A0A194Q2X3;
DT 05-OCT-2016, integrated into UniProtKB/TrEMBL.
DT 05-OCT-2016, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE SubName: Full=Myosin heavy chain, muscle {ECO:0000313|EMBL:KPI99349.1};
GN ORFNames=RR46_05533 {ECO:0000313|EMBL:KPI99349.1};
OS Papilio xuthus (Asian swallowtail butterfly).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Lepidoptera; Glossata; Ditrysia; Papilionoidea;
OC Papilionidae; Papilioninae; Papilio.
OX NCBI_TaxID=66420 {ECO:0000313|EMBL:KPI99349.1, ECO:0000313|Proteomes:UP000053268};
RN [1] {ECO:0000313|EMBL:KPI99349.1, ECO:0000313|Proteomes:UP000053268}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Ya'a_city_454_Px {ECO:0000313|EMBL:KPI99349.1};
RC TISSUE=Whole body {ECO:0000313|EMBL:KPI99349.1};
RX PubMed=26354079; DOI=10.1038/ncomms9212;
RA Li X., Fan D., Zhang W., Liu G., Zhang L., Zhao L., Fang X., Chen L.,
RA Dong Y., Chen Y., Ding Y., Zhao R., Feng M., Zhu Y., Feng Y., Jiang X.,
RA Zhu D., Xiang H., Feng X., Li S., Wang J., Zhang G., Kronforst M.R.,
RA Wang W.;
RT "Outbred genome sequencing and CRISPR/Cas9 gene editing in butterflies.";
RL Nat. Commun. 6:8212-8212(2015).
CC -!- SIMILARITY: Belongs to the TRAFAC class myosin-kinesin ATPase
CC superfamily. Myosin family. {ECO:0000256|ARBA:ARBA00008314,
CC ECO:0000256|PROSITE-ProRule:PRU00782}.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00782}.
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DR EMBL; KQ459580; KPI99349.1; -; Genomic_DNA.
DR STRING; 66420.A0A194Q2X3; -.
DR Proteomes; UP000053268; Unassembled WGS sequence.
DR GO; GO:0016459; C:myosin complex; IEA:UniProtKB-KW.
DR GO; GO:0030017; C:sarcomere; IEA:UniProt.
DR GO; GO:0003779; F:actin binding; IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0003774; F:cytoskeletal motor activity; IEA:InterPro.
DR Gene3D; 1.10.10.820; -; 1.
DR Gene3D; 1.20.5.340; -; 5.
DR Gene3D; 1.20.5.370; -; 4.
DR Gene3D; 1.20.58.530; -; 4.
DR Gene3D; 1.20.58.60; -; 1.
DR Gene3D; 3.30.70.1590; -; 2.
DR Gene3D; 3.40.850.10; Kinesin motor domain; 1.
DR Gene3D; 1.20.120.720; Myosin VI head, motor domain, U50 subdomain; 1.
DR Gene3D; 4.10.270.10; Myosin, subunit A; 1.
DR InterPro; IPR000048; IQ_motif_EF-hand-BS.
DR InterPro; IPR036961; Kinesin_motor_dom_sf.
DR InterPro; IPR001609; Myosin_head_motor_dom.
DR InterPro; IPR002928; Myosin_tail.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR014751; XRCC4-like_C.
DR PANTHER; PTHR45615:SF40; MYOSIN HEAVY CHAIN, MUSCLE-RELATED; 1.
DR PANTHER; PTHR45615; MYOSIN HEAVY CHAIN, NON-MUSCLE; 1.
DR Pfam; PF00063; Myosin_head; 4.
DR Pfam; PF01576; Myosin_tail_1; 1.
DR PRINTS; PR00193; MYOSINHEAVY.
DR SMART; SM00015; IQ; 1.
DR SMART; SM00242; MYSc; 1.
DR SUPFAM; SSF90257; Myosin rod fragments; 6.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 5.
DR PROSITE; PS50096; IQ; 1.
DR PROSITE; PS51456; MYOSIN_MOTOR; 1.
PE 3: Inferred from homology;
KW Actin-binding {ECO:0000256|PROSITE-ProRule:PRU00782};
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054};
KW Motor protein {ECO:0000256|ARBA:ARBA00023175};
KW Muscle protein {ECO:0000256|ARBA:ARBA00023179};
KW Myosin {ECO:0000256|ARBA:ARBA00023123, ECO:0000256|PROSITE-
KW ProRule:PRU00782}; Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000053268};
KW Thick filament {ECO:0000256|ARBA:ARBA00022433}.
FT DOMAIN 1..738
FT /note="Myosin motor"
FT /evidence="ECO:0000259|PROSITE:PS51456"
FT REGION 532..554
FT /note="Actin-binding"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00782"
FT REGION 1880..1922
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1922 AA; 221545 MW; DB9E6D807313FC54 CRC64;
MLSNRIGDYP LISQGKTRIP GVNDSEEFDK TLQAFDILGF TQEEKDNVYK ITAAVMHMGC
MKFKQRGREE QAEADGTEDG DKVAKLLGVD CQDLYKNLLK PRIKVGNEFV TQGRNKDQVT
NSVGALCKGM FDRLFKWLVK KCNETLDTKQ KRQHFIGVLD IAGFEIFDFN GFEQLCINFT
NEKLQQFFNH HMFVLEQEEY TREGIHWEFI DFGMDLVACI DLIEKFNGFE QLCINFTNEK
LQQFFNHHMF VLEQEEYKKE GINWAFIDFG MDLLACIDLI EKYNGFEQLC INFTNEKLQQ
FFNHHMFVLE QEEYQREGIE WTFIDFGMDL QHCIDLIEKM NSFNQLCVNF TNEKLQQYFN
HYMFILEQEE YERERIQWTF IDFGLDLQPT IDLIEKPMGI LSILEEESMF PKATDQTFVE
KLNNNHLGKS APYLKPKPPK PGCQAAHFAI GHYAGNVGYN ITGWLEKNKD PLNDTVVDQF
KKGANKLLVE IFADHPGQSG DASAGGGGKG AGGKRAKGSA FQTVSSLYRE QLNNLMTTLR
STQPHFVRCI IPNELKQAGL IDSHLVMHQL TCNGVLEGIR ICRKGFPNRM VYPDFKLRYM
ILAPALMAAE SDPKIAARKC LESVELDPES YRIGHTKARY YKILAPQAAD KETDPKKVAQ
VILDATGLDP ESYRLGHTKA CLQYKILCPN LLKEPITPEK ATQKILEHTG LDSESFRLGK
TKVFFRAGVL GQMEELRDDR LSKIVSWMQA YIRGYLSRKE YKKLQEQRLA LQVVQRNLRK
YLQLRTWPWW KLWQRVKPLL NVTRIEDEIA KLEEKAQKAQ EAFEKEEKLR KEVEALNAKL
LEEKTALLST LEGEKGSLSE TQERANKLQA QKNDLENQLR DTQDRLTQEE DARNQLFQAK
KKLEQEVSGL KKDIEDLELS VQKSEQDKAT KDHQIRNLND EIAHQDELIN KLNKEKKMQG
ESNQKTSEEL QAAEDKVNHL NKVKQKLEQT LDELEDSLER EKKLRADVEK QRRKVEGDLK
LTQEAVTDLE RNKKELEQTI QRKDKEISSL TAKLEDEQSL VSKLQKQIKE LQARIEELEE
EVESERQARA KAEKQRADLA RELEELGERL EEAGGATSAQ IELNKKREAE LSKLRRDLEE
ANIQHESTLA NLRKKHNDAV AEMGEQLDQL NKLKAKAEKE RSQYFSEVND LRAGLDHLSN
EKAAQEKVVK QLQHNLNEVQ NKADEANRTL NDLDAAKKKL SIENSDLLRQ LEEAESQVSQ
LSKIKVSLTT QLEDTKRLAD EEARERATLL GKFRNLEHDL DNIREQVEEE AEGKADLQRQ
LSKANAEAQL WRSKYESEGV ARSEELEEAK RKLQARLAEA EETIESLNQK VVALEKTKQR
LATEVEDLQL EVDRATAIAN AAEKKQKAFD KIIGEWKLKV DDLAAELDAS QKECRNYSTE
LFRLKGAYEE GQEQLEAVRR ENKNLADEVK DLLDQIGEGG RNIHEIEKAR KRLEAEKDEL
QAALEEAEAA LEQEENKVLR AQLELSQVRQ EIDRRIQEKE EEFENTRKNH QRALDSMQAS
LEAEAKGKAE ALRMKKKLEA DINELEIALD HANKANAEAQ KNIKRYQQQI KDLQTALEEE
QRARDDAREQ LGISERRANA LQNELEESRT LLEQADRARR QAEQELGDAH EQLNELSAQS
ASLSAAKRKL ESELQTLHSD LDELLNEAKN SEEKAKKAMV DAARLADELR AEQEHAQTQE
KLRKALEQQI KELQVRLDEA EANALKGGKK AIQKLEQRVR ELENELDGEQ RRHADAQKNL
RKSERRIKEL SFQAEEDRKN HERMQDLVDK LQQKIKTYKR QIEEAEEIAA LNLAKFRKAQ
QELEEAEERA DLAEQAISKF RGKGRAGSTA RGVSPAPQRT RPALDGFGTF PPRFDLAPES
DF
//
