ID A0A194Q5A4_PAPXU Unreviewed; 5846 AA.
AC A0A194Q5A4;
DT 05-OCT-2016, integrated into UniProtKB/TrEMBL.
DT 05-OCT-2016, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE SubName: Full=Dystonin {ECO:0000313|EMBL:KPJ00723.1};
GN ORFNames=RR46_07562 {ECO:0000313|EMBL:KPJ00723.1};
OS Papilio xuthus (Asian swallowtail butterfly).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Lepidoptera; Glossata; Ditrysia; Papilionoidea;
OC Papilionidae; Papilioninae; Papilio.
OX NCBI_TaxID=66420 {ECO:0000313|EMBL:KPJ00723.1, ECO:0000313|Proteomes:UP000053268};
RN [1] {ECO:0000313|EMBL:KPJ00723.1, ECO:0000313|Proteomes:UP000053268}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Ya'a_city_454_Px {ECO:0000313|EMBL:KPJ00723.1};
RC TISSUE=Whole body {ECO:0000313|EMBL:KPJ00723.1};
RX PubMed=26354079; DOI=10.1038/ncomms9212;
RA Li X., Fan D., Zhang W., Liu G., Zhang L., Zhao L., Fang X., Chen L.,
RA Dong Y., Chen Y., Ding Y., Zhao R., Feng M., Zhu Y., Feng Y., Jiang X.,
RA Zhu D., Xiang H., Feng X., Li S., Wang J., Zhang G., Kronforst M.R.,
RA Wang W.;
RT "Outbred genome sequencing and CRISPR/Cas9 gene editing in butterflies.";
RL Nat. Commun. 6:8212-8212(2015).
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DR EMBL; KQ459460; KPJ00723.1; -; Genomic_DNA.
DR STRING; 66420.A0A194Q5A4; -.
DR Proteomes; UP000053268; Unassembled WGS sequence.
DR GO; GO:0005856; C:cytoskeleton; IEA:InterPro.
DR GO; GO:0045104; P:intermediate filament cytoskeleton organization; IEA:InterPro.
DR CDD; cd00176; SPEC; 6.
DR Gene3D; 1.20.58.60; -; 11.
DR Gene3D; 3.90.1290.10; Plakin repeat; 16.
DR InterPro; IPR043197; Plakin.
DR InterPro; IPR035915; Plakin_repeat_sf.
DR InterPro; IPR001101; Plectin_repeat.
DR InterPro; IPR018159; Spectrin/alpha-actinin.
DR InterPro; IPR002017; Spectrin_repeat.
DR PANTHER; PTHR23169; ENVOPLAKIN; 1.
DR PANTHER; PTHR23169:SF23; SHORT STOP, ISOFORM H; 1.
DR Pfam; PF00681; Plectin; 1.
DR Pfam; PF00435; Spectrin; 6.
DR SMART; SM00250; PLEC; 37.
DR SMART; SM00150; SPEC; 15.
DR SUPFAM; SSF75399; Plakin repeat; 26.
DR SUPFAM; SSF46966; Spectrin repeat; 14.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000053268};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT REGION 2163..2297
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2465..2487
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2615..2662
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 4293..4316
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 4726..4787
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 4174..4215
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 4321..4348
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 4529..4584
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 5079..5154
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 5439..5494
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 5548..5575
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 5659..5686
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 2175..2207
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2224..2246
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2247..2264
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2265..2297
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2465..2482
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2624..2638
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2639..2656
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 4743..4787
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 5846 AA; 653046 MW; 44C48D643516D8A5 CRC64;
MPRNSIFVYR KRVIERSWVE VRLSEESKNA ARIFTEQSSS LLERLEVFER QLHERIASHI
PRDLDSLEHL VLQHKDWETG LHGLATDVEE VQNTFRSIAL KTPAMKKNLD KVMGKWNDMQ
SKSQLFVERL KFVEIIVNSM EENNQTISEF EIKLAQFHDL PNDVEMLKDM HEDLLRMQVA
VSKQQVQVDQ MNDDGDTCRR LVETSRTGLP HASLPRKHPD LERLDKELEQ INTRWNNVCQ
QLAERLRSCE AAYQLLRNYS VGLQQETDWA LLTSVVERTP KIEKVNVDGG RFIREAKIHG
SRCQRYAEWL CEEVHPSLDA RQLKRQGEAE LSQRMQRCGR TAGELSGAEA VARELDELNA
KHQRLLDLLY ERLRRIAAAN PGDIVTLRLV EAMAPRSARS FRQEFNMQDV ATTEHTYTTF
TTEKYVRTSH STEFDGQGPV KSIANGKLTS PNYTTKTILT EEERPDVRKL KRVHKMYEGP
NIIESRGIIH PETREILTVG QAISMRILDV RTGRLLSSPE TRQTMTIEQA AQEGLIDPKL
AARLTGPCGM TEDGNEVTLL EAIQRELYDA EQGLSDPAEK RIKVTVDGEK STTQGMSISD
ALNQGQVDLQ RGLYRLPNGT YITIAEAYQR GFLIYNEIIK IKSSALSLSD AISQDLVDNN
GWILDRNSGD RFQLDVAIRN ELINTEFREI VDHKNDTKIT LAEAIDRNII NTKHSKYIHN
VTKEKFSFKD AASKRYISKP MTLKDVCDNN LMTNDGKILS PANRSPLNIL EAISAGVLDS
DNVKCISNTT TGQLLTLSEA LGARIILTDN KFRDNLTGEL CTIPEAVDRG LITSVSQRSI
FDIDGFRDPK TGEFVSFNTA LSKGNLKYAN GETFLKSESG DFVYLEDCTK VSIIRPEVLE
MFNRKIGVFE NGKELSVLDA VFKNILDPKT GNLLDVTTKK PIPFNKAVEI NMITPEGAAL
LNSLLNITLT LQTVTKTVKR YVTVTNTNTS RRSDSTVTFT EAIQRGLIDE NTQTFTDPTT
GTVFPIQQAL DEGLLGVEKN EPRVARLSDR VTKKDLVPGQ VVELKITKKS FIKDLPPSPE
SKLENDARPE TIKSPEHVRT PFQPHHGITH EIKTVSSKST SLEPTVTSLT IKKNTIELPN
GGWSLKEAIH QKLFDPSTGM FVIPGTDRVL DLEEALKLNI INPESARVID PKTKKELSLH
KALALHILDS TGRYKYVTEI ITMKEAIERK FVILTQITQS TSVHKVITIT SMAGMPDKME
ISEPGQNVDT EDQSALEPVQ VIPGVIFDPA TALTISTTSG ISENILEAVD RGLVPTNSVK
VLDPNSGQRI SLKQAFGKGI IDQRTGEYKD MSGKKITLAD ATKIGLIAVV GAPLVAASKV
IQVVKNTMVK DPKTGEDVPL EVAYERGLVD DLTYKKYEDS LKDKSVSPTP RDDTSSDREI
YERGVIDQNV QEKTQTTSMT TTTTVSQIVT TTILDPKSGE TLSIQEAYDR GLVDSTTYMK
YRDSFKDVSP DKAFVGQEKL LDSNKITSPT QKSISVGAAV SEGFITVESI QNSLLADTVA
KQFLPAKQVK PSPGDVIEID ENALNKTPKY QIKAVKENAS ATLDSKPIVL SKLRKRVISP
SKALEKGLID ENTAQILDSV KLYKDKNGMP ITLKTAIETG LVDQNKGNIK DPVHGYSYSI
KEAIKRGILD EECQDEILIP IAKSLSITEI MQQGLWDDTT KKIVHPETGS LLTLREAIIC
DIIDPLSAVQ VSPGKLITLE EAIEKNVIDT DKNVVKTNRG VLDLVSAVNA DIFPEIKEKP
LENIPLAGMT LAVAIKRGII DPIKGEMKHP LTGEIIPIGE AIEKDLLMGI PYPQSSNTIP
LKDAIAKGYV DLSDYTFTNP ITKEVITVDE AMAQGLLAIK LDPEIVDTTG IVTTITETFT
SQHTVTTKMV ELLADYVLLS ANEVQNTKTG EVISMEEARK KGIVRDEQTN KEQFITSDTN
ISFNDAIMLG YIDLEKGTFT NPKTGETITV TEAVNSGLLN TEIQSSSEPE AKTKELEMLD
LNEAFELLFD EKTQKFRDPK SPNKVMTFKE ALEQKVINPD SVIYKMGSDK SITLQEALHT
GVLDSKSGKV KEPSSGRSLD VKKAAKMGLL AVVAAPVLAG MAVVQGAKAV TSKVISPKQM
IKEKDNIPTM APKSISGKDK KDIDLVTPKQ TVDDKDNLKD KPKNKIAADV AQGENIANKE
DQIISQFKDV KPKKKQSEDQ TKSDETSSKA KLSPLASSQN FLEHEVAKLN EEKSKDSNKI
TPLKKDNEDE VYKPDLNVEK PIEQEIKTPI KQKDDKTVLG EVKKDTQDKL RGIDTKPEVS
NQNDIVISEE RKTSVGDKTS VTFDTHEKVI KGQPTTIKEL PTTSDITVIS RTVSTSIPSE
QIIKHSSTDV TTVTKVTTVS QKQSSTSTVS NTVSVSSKVY KDLGDDNQDQ VDKVIIQEIT
EDEDIKQLQL DDKPHTPEQD NKQSSESVKI TDLVELNKCE QPLEVAKGLI YDPKTKTVIS
LSSGSAEDIA TAVDRGTIST ESVKLLEPTT GKEMTLQEAI DKGIVDQKTG QLKDKSGKSI
NLSQAAQIGL IAVVGAPVLA AAKLIDVVKN AVISDDKEDS NKTSPKSSLS LTSPSQKPDS
DQRTKHQEDK NKVVGEEKPL GISPQVTKTV ENKLLGAEIV HRTPQDTKTI SATFIDAEKQ
PLRDLDEITE QNVTKVKTEQ LKVLYENIPL IDAIMESKIE PKVCRIILNG VESPLTVQDS
LEQEQISRFT PVDVISKNCV IVKESRPKYS ISISQKLTPE ELSEMGVYDI EKQIFLNPET
GSKISFEELV YGLHVFDPAT ILVKDLGSKS DSYVPFDEAI SRHIIDKTTG HMVNPKTGKR
VSFWECVQIG WIVEQPEDVS VIEQTTIETA FEKGLYNPKT GEIKDINTGK LVPIGEAVEK
CLIDHESLLI KLPRTNENIT LSDAIDRGIV EIHEGIITII ETRETIEISV AIQRGIITIT
RRPISIEAAI VNDMYEPISG KIKDAVTEQL VSVEDAVDRN IVHPTISEIK DTALEKFIPL
SEALDSKLVD PETGKYKDKK TGKDIPLDDA LRKGLISTKD VTFSLFDVIE LGYYSPDTGK
ILNPKSGQIV TVKEAIETSL VDPSDVKIKD DKSEAVIPFK QAVTSGLLDL KEGIMTSPVS
NLKDACEKGY LLSDKKPMTL QEGLVQGYYD PDTGLLTINN VTMTLDDAIK IGNINPEALT
VRDSGSGEII TLSDAIKAGI IDSKEGKVRD PVQGDKISLT DASERGLIVP AKRKLSLPEA
VFKGFYDAKT GKFLHPQMKD KIPTDRAIKK RMLDPQSTLV HIGGKVIPFE FAVDKGIVDG
RTGSIMLGDE RVDFREAFER GILVEVRKPL SLIEALEKGV YNEITGLFMD PQSGKKYTLA
EAIKMSLIDP HSVHIQDNRL GKWDKITLTE SMETGVIDNK SGKIRNINNE NEEISLRKAF
EIGLLIDSKA PISLQRALHQ GLYDDSTGKF IDPATSRKIT LHEAIRRSII SSKYLCYFDK
KSEKPLTLAD CCRSEIVDRR SGKFVEPGSD VQIPLSEAMS LGLIVDIESA GFSLYETLAM
NMYNITELVF VHPVTERKIT LKTAITEELV NPEMSLVKNI PSSKYIKLTE AIQTGIIDEN
NSVYILPNGN QINLLDAKHR GLIVNSKKHL SLEEIIRNGL FRADNGKIVD PSTNEFIDIN
KAIEINLINP DLTIVKDSFT NKFKPLLSAI QHGDVDVTKG RVLDTKAKKT YSLDIAFDKG
LLVTVTQPLT SQTITRRYVT DSSALNEPVL REFTLDEAIK YEFIDPKTAL IKDPHKNKYI
PLQLGITEGI IDTNLKGSFD TQTGRSRTLC FTFENGLIVY VREPLTFEQA LENGHLNLTT
ARFTDPHSKE VLTVKDAATL GYIDSDTALI KDNLKKRLVK LPEAFRKGLM DAEKGNILDT
ETSKLNTLSA AIESGLLMTP KKSFTLIETL NFGIYNPTTG ALNDPFITTS IIDRKRLTLG
EAIQQGIVDP SSTVVKEPDT GKIWPLTQAI EQQLINPVEG RLITDPQKGT SIDLVKALKK
GLLLPAETRQ AVEEKYRLCD DTLSKLLEWI AIVEERLANQ EPVKENMDEL RNQINVLKLI
KDDLESHQRQ VSACADQAKQ LLVSGGDVLA PHEVAALERG VRQLKQRFDR CTERCDKMLR
RLAAARDELG KFTNELNTFE SWMEGAYRSL EDKEAALSNL DNLPAYSEEV REFVSDVIAH
QADLRFITMA AQKFIDESKE FVSIVNEQRA SLESRSAPLS ARGDQVRDAA GSARRRHSEL
AARAQRLLDR LRTAHAALQR HRAALQRAQQ WLQDLEPQVR SALEEGVGGE PRAVKAQLQR
VKALHNEILS QGRLVDNAKE ACEQLLNSLE GNITPSEARQ LESPVQQLVS RVSELGAAVA
ERCADLEAAL LHCQGLQDAA EAQANWLAQA ENAFKNQQKP ASLIRERLDE QVREQRLAHG
EAEARRATLA KLLAGAREAA RAPSNARIAK KLEQRAEDIY ARYEKLVERS SKRGQFLEEV
SSELARFTQQ AAKLEAAHSQ LLEMGDTRLH ELSAARDKQM PLLEECLRNG KQLLAKKDVT
DTHVVRDRIK ALENQWRDFN TSLEEKQKLS KQRADHLNQY ETLRIQVIEW LHIMEEKVSR
LQPVAVDLDI VKVQHEELRP LTKEYRDFSI NIDKVNEAGA LYENLTRGER ADSPHRRRQI
YSPTKRQTPT RSLDARSPSP SKGHMVSPGS HSASSGFSSR RSSQDGFHLE ELSPVQQQLS
DINNRYGLVG SKLSDRQAEI DSIRDEIRKH LDNFRALNNF LDKVQRQLPK ESVPNTKDEA
DKTIKQARAV LEEMYEKQSL LDSTKTQIHE LLKRKQSAQG ADRLHDELKD LASRWKSLHD
AFKDKIRLME EMKDFHDTYN NLSQWLSAKD RMMAALGPIS SDSRMVQTQV QQVQVLREEF
RGQQPQLSHL EQVGAAVLDR LEPDSPDATK LRQKVHELQD KWNRLLDQLE QRAASLGAAA
DTCRELDAGL ARLRDTLTAI SDRLDAAPLH PADDRLRSIE NLERQLEGQR PLLADLEAAG
EALGAVLGEP AARQDVAHKL AGAARQYEAL QRRLDMAKAE AEAALKEGRN LEESVSRTLG
WLQTELGSLP GRLRVSAARA TLQQQLDKHE PLYRQLNQRE HEIIMLLDKG REMEKKPSHQ
GLRKDLDRIQ TQWDKLKRET VDRYTRLQTA MEHCRKYSKA QENFLPWLSD TEERLLKLPP
TTFTKKEVEK QLRELQQIRN DIWKRSGEFE NNKTLGETFI SACDVDQEVV RDQIDSMKER
WDRINNEVLQ HVEFLESTLR KLGEFLERVR GVEAPLQRCE ERLEAVSSVP PHAAHDAVAR
VADQLHALRA PLQSVHSAAE DIISLALECA GPEVAERARP VLEETARALS DRLQQLEARA
DTARDQLAGA TAALAHFQDK VKGVSHDLSD LEKELDSMKA PGRDVKTVRQ QLDDLGRFYK
RLENADDLIA DAERAAAGLV DSGHSVDVTK TRDQVEGLRK QLGKLDERAR SKEQDLEDTL
SKLEAFYKAY DAVMEDVQEA TEQVRSLKPV SSEVEQIRSQ QKDFADLKTK TLEPLGQNVA
HCNKIGQGLV RSANQGVSTQ TLEKDLEKMN DRWNALKEKM NERERRLDVG LLQSGKFAEA
LAGLEKWLSD TEDMVHNQKP PSADYKVVKA QLQEQKFLKK MLMDRQNSMS SLFAMGNEVA
AGCEPAERKA VEKQLKALMQ RFDALTDGAQ QRMLDLEQAM KVAKLFQEQL QPLVEWLSSA
ERQVKALELV PTDEEKIQQK IREHKV
//
