ID   A0A194QBS0_PAPXU        Unreviewed;       381 AA.
AC   A0A194QBS0;
DT   05-OCT-2016, integrated into UniProtKB/TrEMBL.
DT   05-OCT-2016, sequence version 1.
DT   27-MAR-2024, entry version 19.
DE   RecName: Full=Lipase {ECO:0000256|PIRNR:PIRNR000862};
GN   ORFNames=RR46_06161 {ECO:0000313|EMBL:KPJ03003.1};
OS   Papilio xuthus (Asian swallowtail butterfly).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Lepidoptera; Glossata; Ditrysia; Papilionoidea;
OC   Papilionidae; Papilioninae; Papilio.
OX   NCBI_TaxID=66420 {ECO:0000313|EMBL:KPJ03003.1, ECO:0000313|Proteomes:UP000053268};
RN   [1] {ECO:0000313|EMBL:KPJ03003.1, ECO:0000313|Proteomes:UP000053268}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Ya'a_city_454_Px {ECO:0000313|EMBL:KPJ03003.1};
RC   TISSUE=Whole body {ECO:0000313|EMBL:KPJ03003.1};
RX   PubMed=26354079; DOI=10.1038/ncomms9212;
RA   Li X., Fan D., Zhang W., Liu G., Zhang L., Zhao L., Fang X., Chen L.,
RA   Dong Y., Chen Y., Ding Y., Zhao R., Feng M., Zhu Y., Feng Y., Jiang X.,
RA   Zhu D., Xiang H., Feng X., Li S., Wang J., Zhang G., Kronforst M.R.,
RA   Wang W.;
RT   "Outbred genome sequencing and CRISPR/Cas9 gene editing in butterflies.";
RL   Nat. Commun. 6:8212-8212(2015).
CC   -!- SIMILARITY: Belongs to the AB hydrolase superfamily. Lipase family.
CC       {ECO:0000256|ARBA:ARBA00010701, ECO:0000256|PIRNR:PIRNR000862}.
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DR   EMBL; KQ459193; KPJ03003.1; -; Genomic_DNA.
DR   RefSeq; XP_013165561.1; XM_013310107.1.
DR   AlphaFoldDB; A0A194QBS0; -.
DR   STRING; 66420.A0A194QBS0; -.
DR   GeneID; 106116322; -.
DR   KEGG; pxu:106116322; -.
DR   OrthoDB; 3259424at2759; -.
DR   Proteomes; UP000053268; Unassembled WGS sequence.
DR   GO; GO:0016788; F:hydrolase activity, acting on ester bonds; IEA:InterPro.
DR   GO; GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.50.1820; alpha/beta hydrolase; 1.
DR   InterPro; IPR029058; AB_hydrolase.
DR   InterPro; IPR006693; AB_hydrolase_lipase.
DR   InterPro; IPR025483; Lipase_euk.
DR   PANTHER; PTHR11005:SF147; LIPASE-RELATED; 1.
DR   PANTHER; PTHR11005; LYSOSOMAL ACID LIPASE-RELATED; 1.
DR   Pfam; PF04083; Abhydro_lipase; 1.
DR   PIRSF; PIRSF000862; Steryl_ester_lip; 1.
DR   SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
PE   3: Inferred from homology;
KW   Hydrolase {ECO:0000256|PIRNR:PIRNR000862};
KW   Lipid degradation {ECO:0000256|PIRNR:PIRNR000862};
KW   Lipid metabolism {ECO:0000256|PIRNR:PIRNR000862};
KW   Reference proteome {ECO:0000313|Proteomes:UP000053268}.
FT   DOMAIN          12..69
FT                   /note="Partial AB-hydrolase lipase"
FT                   /evidence="ECO:0000259|Pfam:PF04083"
FT   ACT_SITE        148
FT                   /note="Nucleophile"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR000862-1"
FT   ACT_SITE        322
FT                   /note="Charge relay system"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR000862-1"
FT   ACT_SITE        353
FT                   /note="Charge relay system"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR000862-1"
SQ   SEQUENCE   381 AA;  42616 MW;  F2E1B4E7D165412D CRC64;
     MGYPPDSLDN FTELATKYGY VSEEHTVTTE DGYILTMFRI TKGKNCNGPI RKPPVILMHG
     LLMSSDCFLD AGQDAGLAYL ISDLCYDLWV PNVRGNYYSK RHIDLDPATD NEFWDFSNLE
     FGYYDVPAFI DYILSKTKSK KLNYVGFSQG CSSFSIMNAE RQEYNDKIGV AILIEPSSRQ
     TNMRSQLTRL LFSTAATSLP ALTSVGHCEV LSLGGIVQEI AAFLCKDYIA ANTLCRVVMS
     SIDASHPGSV TTQTMRVLFG HFPAGTSTKN LAWYGQGLNT NTFQNFDYGV EENLQIYGSD
     QPPPYNLSQV TVPIVIINGN NDGLATPADV DWLTSKLPNV LEHFLVQDPL WDHLDVVYSQ
     YTRKSILPKI SQYLRSYSTY T
//