ID A0A194QG82_PAPXU Unreviewed; 610 AA.
AC A0A194QG82;
DT 05-OCT-2016, integrated into UniProtKB/TrEMBL.
DT 05-OCT-2016, sequence version 1.
DT 22-FEB-2023, entry version 21.
DE SubName: Full=X-ray repair cross-complementing protein 5 {ECO:0000313|EMBL:KPJ02456.1};
GN ORFNames=RR46_09659 {ECO:0000313|EMBL:KPJ02456.1};
OS Papilio xuthus (Asian swallowtail butterfly).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Lepidoptera; Glossata; Ditrysia; Papilionoidea;
OC Papilionidae; Papilioninae; Papilio.
OX NCBI_TaxID=66420 {ECO:0000313|EMBL:KPJ02456.1, ECO:0000313|Proteomes:UP000053268};
RN [1] {ECO:0000313|EMBL:KPJ02456.1, ECO:0000313|Proteomes:UP000053268}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Ya'a_city_454_Px {ECO:0000313|EMBL:KPJ02456.1};
RC TISSUE=Whole body {ECO:0000313|EMBL:KPJ02456.1};
RX PubMed=26354079; DOI=10.1038/ncomms9212;
RA Li X., Fan D., Zhang W., Liu G., Zhang L., Zhao L., Fang X., Chen L.,
RA Dong Y., Chen Y., Ding Y., Zhao R., Feng M., Zhu Y., Feng Y., Jiang X.,
RA Zhu D., Xiang H., Feng X., Li S., Wang J., Zhang G., Kronforst M.R.,
RA Wang W.;
RT "Outbred genome sequencing and CRISPR/Cas9 gene editing in butterflies.";
RL Nat. Commun. 6:8212-8212(2015).
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR EMBL; KQ459232; KPJ02456.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A194QG82; -.
DR STRING; 66420.A0A194QG82; -.
DR Proteomes; UP000053268; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR GO; GO:0006310; P:DNA recombination; IEA:UniProtKB-KW.
DR GO; GO:0006303; P:double-strand break repair via nonhomologous end joining; IEA:InterPro.
DR Gene3D; 1.10.1600.10; -; 1.
DR Gene3D; 2.40.290.10; -; 1.
DR Gene3D; 1.25.40.240; Ku, C-terminal domain; 1.
DR Gene3D; 3.40.50.410; von Willebrand factor, type A domain; 1.
DR InterPro; IPR006164; Ku70/Ku80_beta-barrel_dom.
DR InterPro; IPR036494; Ku_C_sf.
DR InterPro; IPR014893; Ku_PK_bind.
DR InterPro; IPR016194; SPOC-like_C_dom_sf.
DR InterPro; IPR036465; vWFA_dom_sf.
DR PANTHER; PTHR12604; KU AUTOANTIGEN DNA HELICASE; 1.
DR PANTHER; PTHR12604:SF4; X-RAY REPAIR CROSS-COMPLEMENTING PROTEIN 5; 1.
DR Pfam; PF02735; Ku; 1.
DR Pfam; PF08785; Ku_PK_bind; 1.
DR SMART; SM00559; Ku78; 1.
DR SUPFAM; SSF101420; C-terminal domain of Ku80; 1.
DR SUPFAM; SSF100939; SPOC domain-like; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW DNA damage {ECO:0000256|ARBA:ARBA00022763};
KW DNA recombination {ECO:0000256|ARBA:ARBA00023172};
KW DNA repair {ECO:0000256|ARBA:ARBA00023204};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Helicase {ECO:0000256|ARBA:ARBA00022806};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000053268}.
FT DOMAIN 206..344
FT /note="Ku"
FT /evidence="ECO:0000259|SMART:SM00559"
SQ SEQUENCE 610 AA; 69707 MW; 69A40F4B3E51C33D CRC64;
MTQGTVIIFD IGPNTLVLDG NDKSFFQRSK EFITRVIERK IMTLDKEPLA LFLMGCENAG
ISCVNFKFEI PSWNMIRNLP CEIKNQLVNE NFQVDVIGCD LFEEPCTDSD KNLAKIIVND
TNGVSILFDD AMRQLNFYKK KHVAGNPWLV DLCIGPNINI PISSYIRTQK ETPLKTWIEA
IRDPITNRAS TVVRVNKKKL YINAENKVVN NKDIVKGVHY GGIIIPLSSL DKNFNYIAES
KSLNIYCFTS ASNLKWENLN YDSLSYIFGR KDDKNACNTI RCLAECLMAR NMIAIARGVK
KKNCAPRMYA LMPVKENKTL CLSMVGICYK EEIKHMIFPQ TECKKFTCSR EQIDAFKDLI
KAMNLNTDEL EGSEAFEFSK VPSPYAQYAY DSIVFRANNP DKPLPKPRDD IINLFQVPTL
IKMRATEPIE KLKSLFVLNK INANQIDNSE AMVVTDDVEN IKTESIEYIE SKSIGTVNPI
NDYNLLLSLG RPLNTISQEM SNAIETLFNS NSDQHKCKAI DAMLFFRAES VKDNPIFYNK
WLKGFKMELI DRKKDDIIKL IEEKEMDFIL NNENELSELK SVDSEMCKMD TCNLIDVAIS
SEVTDFFDNM
//
