ID   A0A194S107_RHOGW        Unreviewed;       547 AA.
AC   A0A194S107;
DT   05-OCT-2016, integrated into UniProtKB/TrEMBL.
DT   05-OCT-2016, sequence version 1.
DT   27-MAR-2024, entry version 27.
DE   RecName: Full=Phytoene desaturase {ECO:0000256|ARBA:ARBA00013293};
DE   AltName: Full=Phytoene desaturase (3,4-didehydrolycopene-forming) {ECO:0000256|ARBA:ARBA00034551};
GN   ORFNames=RHOBADRAFT_16107 {ECO:0000313|EMBL:KPV74225.1};
OS   Rhodotorula graminis (strain WP1).
OC   Eukaryota; Fungi; Dikarya; Basidiomycota; Pucciniomycotina;
OC   Microbotryomycetes; Sporidiobolales; Sporidiobolaceae; Rhodotorula.
OX   NCBI_TaxID=578459 {ECO:0000313|EMBL:KPV74225.1, ECO:0000313|Proteomes:UP000053890};
RN   [1] {ECO:0000313|EMBL:KPV74225.1, ECO:0000313|Proteomes:UP000053890}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=WP1 {ECO:0000313|EMBL:KPV74225.1,
RC   ECO:0000313|Proteomes:UP000053890};
RX   PubMed=26441909; DOI=10.3389/fmicb.2015.00978;
RA   Firrincieli A., Otillar R., Salamov A., Schmutz J., Khan Z., Redman R.S.,
RA   Fleck N.D., Lindquist E., Grigoriev I.V., Doty S.L.;
RT   "Genome sequence of the plant growth promoting endophytic yeast Rhodotorula
RT   graminis WP1.";
RL   Front. Microbiol. 6:978-978(2015).
CC   -!- COFACTOR:
CC       Name=NAD(+); Xref=ChEBI:CHEBI:57540;
CC         Evidence={ECO:0000256|ARBA:ARBA00001911};
CC   -!- PATHWAY: Carotenoid biosynthesis. {ECO:0000256|ARBA:ARBA00004829,
CC       ECO:0000256|RuleBase:RU362075}.
CC   -!- SIMILARITY: Belongs to the carotenoid/retinoid oxidoreductase family.
CC       {ECO:0000256|ARBA:ARBA00006046, ECO:0000256|RuleBase:RU362075}.
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DR   EMBL; KQ474080; KPV74225.1; -; Genomic_DNA.
DR   RefSeq; XP_018270274.1; XM_018412298.1.
DR   AlphaFoldDB; A0A194S107; -.
DR   STRING; 578459.A0A194S107; -.
DR   GeneID; 28972747; -.
DR   OMA; INYPKGG; -.
DR   OrthoDB; 5490570at2759; -.
DR   Proteomes; UP000053890; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:UniProt.
DR   GO; GO:0016627; F:oxidoreductase activity, acting on the CH-CH group of donors; IEA:UniProt.
DR   GO; GO:0016117; P:carotenoid biosynthetic process; IEA:UniProtKB-KW.
DR   Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 2.
DR   InterPro; IPR002937; Amino_oxidase.
DR   InterPro; IPR014105; Carotenoid/retinoid_OxRdtase.
DR   InterPro; IPR036188; FAD/NAD-bd_sf.
DR   InterPro; IPR008150; Phytoene_DH_bac_CS.
DR   NCBIfam; TIGR02734; crtI_fam; 1.
DR   PANTHER; PTHR43734; PHYTOENE DESATURASE; 1.
DR   PANTHER; PTHR43734:SF1; PHYTOENE DESATURASE; 1.
DR   Pfam; PF01593; Amino_oxidase; 1.
DR   SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
DR   PROSITE; PS00982; PHYTOENE_DH; 1.
PE   3: Inferred from homology;
KW   Carotenoid biosynthesis {ECO:0000256|ARBA:ARBA00022746,
KW   ECO:0000256|RuleBase:RU362075}; Membrane {ECO:0000256|SAM:Phobius};
KW   Oxidoreductase {ECO:0000256|RuleBase:RU362075};
KW   Reference proteome {ECO:0000313|Proteomes:UP000053890};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        524..545
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          16..496
FT                   /note="Amine oxidase"
FT                   /evidence="ECO:0000259|Pfam:PF01593"
SQ   SEQUENCE   547 AA;  60801 MW;  304A620E7DFEE45B CRC64;
     MAPRPSVIIV GAGVGGTSSA ARLAQAGFDV QVVEKNDFAG GRCSLFTDPT GEHRFDMGPS
     LYLIPRLFEE TFSDLGTSLD AEGIKLVKCE PNYRIVFPDK EVVEMSSDLT KMKKEVEKWE
     GEKGFEGFLG FLKEGHAHYE LSMVHVLHRN FTSYLSLLRP SLIVNLSKLH PFVSVYTRAT
     KYFKTERMRR AFTFAAMYLG MSPFDALGAY NLLQYTEHCE GILYPLGGFG TVPKALQRIA
     ERNGAKFRFN STVKRVVVQD GKAKGVELEG GEILSADIVL VNADLVWSMA HLYQETAYSK
     RLEEKPVSCS SISFYWAMKR SVPELGSHTI FLADEYKESF DSIFRDHKIP HEPSFYVNVP
     SRHDPSAAPA DKDTVIVLVP VGHISKALPT SSDWDKVVEE TRNKVIREVE GRLGMTNFRD
     LIAHETVNTP ITWGEKFNLH RGSILGLSHD FFNVLSFRPK TRHPTVKNAY FVGASAHPGT
     GVPIVLAGAR MATTQIIDDL GKQTPKEWNV SSSELATHRT GRDAMGGIGL LMALAALFLA
     IAVYLRQ
//