ID A0A1A6C5F0_9GAMM Unreviewed; 115 AA.
AC A0A1A6C5F0;
DT 05-OCT-2016, integrated into UniProtKB/TrEMBL.
DT 05-OCT-2016, sequence version 1.
DT 24-JAN-2024, entry version 22.
DE RecName: Full=Negative regulator of flagellin synthesis {ECO:0000256|ARBA:ARBA00017823};
DE AltName: Full=Anti-sigma-28 factor {ECO:0000256|ARBA:ARBA00030117};
GN ORFNames=Thpro_020837 {ECO:0000313|EMBL:OBS09787.1};
OS Acidihalobacter prosperus.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Chromatiales;
OC Ectothiorhodospiraceae; Acidihalobacter.
OX NCBI_TaxID=160660 {ECO:0000313|EMBL:OBS09787.1, ECO:0000313|Proteomes:UP000029273};
RN [1] {ECO:0000313|EMBL:OBS09787.1, ECO:0000313|Proteomes:UP000029273}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 5130 {ECO:0000313|EMBL:OBS09787.1,
RC ECO:0000313|Proteomes:UP000029273};
RX PubMed=25342676;
RA Ossandon F.J., Cardenas J.P., Corbett M., Quatrini R., Holmes D.S.,
RA Watkin E.;
RT "Draft Genome Sequence of the Iron-Oxidizing, Acidophilic, and Halotolerant
RT 'Thiobacillus prosperus' Type Strain DSM 5130.";
RL Genome Announc. 2:0-0(2014).
CC -!- FUNCTION: Responsible for the coupling of flagellin expression to
CC flagellar assembly by preventing expression of the flagellin genes when
CC a component of the middle class of proteins is defective. It negatively
CC regulates flagellar genes by inhibiting the activity of FliA by
CC directly binding to FliA. {ECO:0000256|ARBA:ARBA00024739}.
CC -!- SIMILARITY: Belongs to the FlgM family.
CC {ECO:0000256|ARBA:ARBA00005322}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OBS09787.1}.
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DR EMBL; JQSG02000002; OBS09787.1; -; Genomic_DNA.
DR RefSeq; WP_038092278.1; NZ_JQSG02000002.1.
DR AlphaFoldDB; A0A1A6C5F0; -.
DR OrthoDB; 5797147at2; -.
DR Proteomes; UP000029273; Unassembled WGS sequence.
DR GO; GO:0044781; P:bacterial-type flagellum organization; IEA:UniProtKB-KW.
DR GO; GO:0045892; P:negative regulation of DNA-templated transcription; IEA:InterPro.
DR InterPro; IPR035890; Anti-sigma-28_factor_FlgM_sf.
DR InterPro; IPR007412; FlgM.
DR InterPro; IPR031316; FlgM_C.
DR NCBIfam; TIGR03824; FlgM_jcvi; 1.
DR Pfam; PF04316; FlgM; 1.
DR SUPFAM; SSF101498; Anti-sigma factor FlgM; 1.
PE 3: Inferred from homology;
KW Bacterial flagellum biogenesis {ECO:0000256|ARBA:ARBA00022795};
KW Cell projection {ECO:0000313|EMBL:OBS09787.1};
KW Cilium {ECO:0000313|EMBL:OBS09787.1};
KW Flagellum {ECO:0000313|EMBL:OBS09787.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000029273};
KW Repressor {ECO:0000256|ARBA:ARBA00022491};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 52..105
FT /note="Anti-sigma-28 factor FlgM C-terminal"
FT /evidence="ECO:0000259|Pfam:PF04316"
FT REGION 1..57
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 115 AA; 11704 MW; 669061CA56293239 CRC64;
MNIDLKNVPQ QGGTKGAGET AGPSSRTAVQ QGAPRESAGA AQSSGAPAAS GDSVSLTRGG
QQLAQLQAGL AQQPVVDKQR VAELRQAIQS GQYHVNPGQV ADKLLGFEGQ AKQRS
//
