ID A0A1B8XZ29_XENTR Unreviewed; 1603 AA.
AC A0A1B8XZ29;
DT 02-NOV-2016, integrated into UniProtKB/TrEMBL.
DT 02-NOV-2016, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE RecName: Full=CKK domain-containing protein {ECO:0000259|PROSITE:PS51508};
GN ORFNames=XENTR_v90028934mg {ECO:0000313|EMBL:OCA15937.1};
OS Xenopus tropicalis (Western clawed frog) (Silurana tropicalis).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana.
OX NCBI_TaxID=8364 {ECO:0000313|EMBL:OCA15937.1};
RN [1] {ECO:0000313|EMBL:OCA15937.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Nigerian {ECO:0000313|EMBL:OCA15937.1};
RG US DOE Joint Genome Institute (JGI-PGF);
RA Ottilar R., Schmutz J., Salamov A., Cheng J.F., Lucas S., Pitluck S.,
RA Gundlach H., Guo Y., Haberer G., Nasrallah J., Mayer K.F.X.,
RA van de Peer Y., Weigel D., Grigoriev I.V.;
RL Submitted (NOV-2009) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:OCA15937.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Nigerian {ECO:0000313|EMBL:OCA15937.1};
RX PubMed=20431018; DOI=10.1126/science.1183670;
RA Hellsten U., Harland R.M., Gilchrist M.J., Hendrix D., Jurka J.,
RA Kapitonov V., Ovcharenko I., Putnam N.H., Shu S., Taher L., Blitz I.L.,
RA Blumberg B., Dichmann D.S., Dubchak I., Amaya E., Detter J.C., Fletcher R.,
RA Gerhard D.S., Goodstein D., Graves T., Grigoriev I.V., Grimwood J.,
RA Kawashima T., Lindquist E., Lucas S.M., Mead P.E., Mitros T., Ogino H.,
RA Ohta Y., Poliakov A.V., Pollet N., Robert J., Salamov A., Sater A.K.,
RA Schmutz J., Terry A., Vize P.D., Warren W.C., Wells D., Wills A.,
RA Wilson R.K., Zimmerman L.B., Zorn A.M., Grainger R., Grammer T.,
RA Khokha M.K., Richardson P.M., Rokhsar D.S.;
RT "The genome of the Western clawed frog Xenopus tropicalis.";
RL Science 328:633-636(2010).
RN [3] {ECO:0000313|EMBL:OCA15937.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Nigerian {ECO:0000313|EMBL:OCA15937.1};
RA Sessions A., Jenkins J., Mitros T., Lyons J.T., Dichmann D.S., Robert J.,
RA Harland R.M., Rokhsar D.S.;
RT "WGS assembly of Xenopus tropicalis.";
RL Submitted (MAY-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton
CC {ECO:0000256|ARBA:ARBA00004245}.
CC -!- DOMAIN: The CKK domain binds microtubules. {ECO:0000256|PROSITE-
CC ProRule:PRU00841}.
CC -!- SIMILARITY: Belongs to the CAMSAP1 family. {ECO:0000256|PROSITE-
CC ProRule:PRU00841}.
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DR EMBL; KV460705; OCA15937.1; -; Genomic_DNA.
DR GO; GO:0005874; C:microtubule; IEA:UniProtKB-UniRule.
DR GO; GO:0005516; F:calmodulin binding; IEA:InterPro.
DR GO; GO:0008017; F:microtubule binding; IEA:InterPro.
DR GO; GO:0030507; F:spectrin binding; IEA:InterPro.
DR GO; GO:0031175; P:neuron projection development; IEA:InterPro.
DR CDD; cd22265; UDM1_RNF168; 1.
DR Gene3D; 3.10.20.360; CKK domain; 1.
DR InterPro; IPR032940; CAMSAP.
DR InterPro; IPR022613; CAMSAP-like_CH_dom.
DR InterPro; IPR031372; CAMSAP_CC1.
DR InterPro; IPR038209; CKK_dom_sf.
DR InterPro; IPR014797; CKK_domain.
DR InterPro; IPR011033; PRC_barrel-like_sf.
DR PANTHER; PTHR21595:SF3; CALMODULIN-REGULATED SPECTRIN-ASSOCIATED PROTEIN 1; 1.
DR PANTHER; PTHR21595; UNCHARACTERIZED; 1.
DR Pfam; PF17095; CAMSAP_CC1; 1.
DR Pfam; PF11971; CAMSAP_CH; 1.
DR Pfam; PF08683; CAMSAP_CKK; 1.
DR SMART; SM01051; CAMSAP_CKK; 1.
DR SUPFAM; SSF50346; PRC-barrel domain; 1.
DR PROSITE; PS51508; CKK; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00023212};
KW Cytoskeleton {ECO:0000256|ARBA:ARBA00023212};
KW Microtubule {ECO:0000256|ARBA:ARBA00022701, ECO:0000256|PROSITE-
KW ProRule:PRU00841}.
FT DOMAIN 1417..1551
FT /note="CKK"
FT /evidence="ECO:0000259|PROSITE:PS51508"
FT REGION 326..358
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 398..427
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 524..557
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 572..603
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 731..759
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 789..813
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1033..1126
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1156..1216
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1245..1403
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 838..868
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 971..998
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 328..358
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 524..544
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 573..592
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 731..753
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 789..807
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1067..1085
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1172..1186
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1201..1216
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1245..1302
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1336..1371
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1603 AA; 178459 MW; 64246A13C9A04B4E CRC64;
MVDVGLSASG DGTRRKMESL ADGTVEVVPL DMYDSFRAKI AANLQWICAK AYGIDNVPEE
LKDPFYTDQY EQEHIKPPVI KLLLSSELYC RVCSLILKGD QVAALQGHQP VIQALSQKGI
YVMESDEAPV SDSDLSCSPI KMSAHMSMID ALMMAYTVEM ISIEKVVASV KRFSTFSASK
ELPYDLEDAM VFWINKVNLK MREILEREHR IKQQVIESPS HPKVKQIMYR ECPPGRESAA
RGISLQVYIC LKEVTSIADS LYNIQLLKEF SNEYLNKCFF LTLEDMLYSP LVLKPNVMVF
IAELFWWFEN VKPDFVQPRD TQELKEAKVA TQPKSSRPQV PISNATKRSF LASPPSTGDC
QAAAASDSCS RNYLQPEDAE NGKGCTVFSP SHPLLPLRQK QQKSVQPEES PNHRDRANSL
TRADGQPMAS IIAWPEKKLR PLSQPFGFHH GADDVDATSG DSISLARSIS KDSLASNIIS
ATPKHQTFPT PMNVGSKSLL GNVDIEDDEE ELVAFIRSDD TSCPGDLELQ SVSSRASSQM
SATRPRRPGD LESKPDSFFL EPLMPAVLKP AKEKQMVPKR EEYGEGKQKG FSSKRQNEGN
QSFSRKKIIN NHTGHDLNRT FTPLSSLESA CVTAPLRTDP AQLSIENGNG TFRPLATSSV
EPNEPVGGFF LHDINDDEVE EKPSVGSLMI EDPRKSDTTW TVLPDSEHLD IGEGEQEVVV
ARAFGKHIGE EESAKLQEDM KVKEHDDKDD ASGRSSPCLS TISQISSASM ASGSIRMTSF
AERKFQRLNS YETKSSTSSS QKTTPDGSEC CPLPLTTWKQ RREQSPGRQN KDHANVLASE
LVQLHMQLEE KRRAIEAQKK KMESLSARQR LKLGKAAFLH VVKKGKPDTV PQPVKPGHSL
KDYTKRVPED IDAVSVNAKV EQYLETIEPG DLKVQEAFAD PKQKDPASLE ADICNLIASS
TPDDADSEID VNECDLSIEK LNETISTLQQ AILKISQQQE MLMKAPAMAV PPLPNNGQEH
KLKPSVQFVE PISPPGVPVA RKTPRFGQGR NPRSLRIPEQ KTAKEKALSS SRVITPTNSI
ETVPHLKSVQ PPKSPNLPAE EPPADIVPEQ GSAYQDKPTT GGFRLHEDNN QRTFVLSASK
DANIISEQMH REAVASLRVA GGSAPESSGK ENVPVDEQNK NKSSLIEVDL SDLKETDEEG
EETDHPEKTK DIISDDQKSG LGFFFKDEQK AEDELAKKRA AFLMKQQRKA EEARIRKQQL
EAEVEQKRDE ARRKAEEDRI RKDEEKARRE LIKQEYLRRK QQQILEEQGL GRPKPKPKPR
KTRPKSVHRE ESYSDSGTKY SSTPDNLSSA QSGSSLSLAS GATTEAESVH SGGTPSHRVD
CVDSLSGMGR HQSRNAERDW ENASTASSIA SVAEYSGPKL YKEPSSKSNK PIIHNAISHC
CLAGKVNETV KNSTLEELEK CDSNHYIILF RDAGCQFRAL YSYYPDTEEI CKLMGTGPKN
ITKKMIDKLY KYSSDRKQFT VIPAKTMSAS VDALTIHNHL GKPRGPPCQR RTPCASKHLL
GRCIWFREQN VYFIFTRGYK FCCTLNVFTF PLPPPPSGGE DNY
//
