ID A0B7R7_METTP Unreviewed; 281 AA.
AC A0B7R7;
DT 28-NOV-2006, integrated into UniProtKB/TrEMBL.
DT 28-NOV-2006, sequence version 1.
DT 27-MAR-2024, entry version 86.
DE SubName: Full=dTDP-4-dehydrorhamnose reductase {ECO:0000313|EMBL:ABK14741.1};
DE EC=1.1.1.133 {ECO:0000313|EMBL:ABK14741.1};
GN OrderedLocusNames=Mthe_0953 {ECO:0000313|EMBL:ABK14741.1};
OS Methanothrix thermoacetophila (strain DSM 6194 / JCM 14653 / NBRC 101360 /
OS PT) (Methanosaeta thermophila).
OC Archaea; Euryarchaeota; Stenosarchaea group; Methanomicrobia;
OC Methanotrichales; Methanotrichaceae; Methanothrix.
OX NCBI_TaxID=349307 {ECO:0000313|EMBL:ABK14741.1, ECO:0000313|Proteomes:UP000000674};
RN [1] {ECO:0000313|EMBL:ABK14741.1, ECO:0000313|Proteomes:UP000000674}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 6194 / JCM 14653 / NBRC 101360 / PT
RC {ECO:0000313|Proteomes:UP000000674};
RG US DOE Joint Genome Institute;
RA Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C.,
RA Glavina del Rio T., Hammon N., Israni S., Pitluck S., Chain P.,
RA Malfatti S., Shin M., Vergez L., Schmutz J., Larimer F., Land M.,
RA Hauser L., Kyrpides N., Kim E., Smith K.S., Ingram-Smith C., Richardson P.;
RT "Complete sequence of Methanosaeta thermophila PT.";
RL Submitted (OCT-2006) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; CP000477; ABK14741.1; -; Genomic_DNA.
DR AlphaFoldDB; A0B7R7; -.
DR STRING; 349307.Mthe_0953; -.
DR KEGG; mtp:Mthe_0953; -.
DR HOGENOM; CLU_045518_1_2_2; -.
DR OrthoDB; 4907at2157; -.
DR Proteomes; UP000000674; Chromosome.
DR GO; GO:0008831; F:dTDP-4-dehydrorhamnose reductase activity; IEA:UniProtKB-EC.
DR CDD; cd05254; dTDP_HR_like_SDR_e; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR Gene3D; 3.90.25.10; UDP-galactose 4-epimerase, domain 1; 1.
DR InterPro; IPR005913; dTDP_dehydrorham_reduct.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR029903; RmlD-like-bd.
DR NCBIfam; TIGR01214; rmlD; 1.
DR PANTHER; PTHR10491; DTDP-4-DEHYDRORHAMNOSE REDUCTASE; 1.
DR PANTHER; PTHR10491:SF4; METHIONINE ADENOSYLTRANSFERASE 2 SUBUNIT BETA; 1.
DR Pfam; PF04321; RmlD_sub_bind; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE 4: Predicted;
KW Oxidoreductase {ECO:0000313|EMBL:ABK14741.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000000674}.
FT DOMAIN 1..277
FT /note="RmlD-like substrate binding"
FT /evidence="ECO:0000259|Pfam:PF04321"
SQ SEQUENCE 281 AA; 31324 MW; 086B06B8E4BA7832 CRC64;
MRILIFGAEG QLGTELCRVL GHHDLAPFSH IEADVADLGA VLRQTERIRP DVIINSAAYT
DVDGCESARD KAVLVNAIGA RNAAIAARRA GAKFVHISTD YVFDGKKDGP YVEYDPPNPL
NVYGWSKLLG ERMVLEQNPD SFILRVAWLY GPAGRNFVKT MLSLARARDE LRVVNDQRGT
PTFAGDVANQ IDLLIETESY GLYHCTSQGE CTWYEFAVEI FRLLGMDLRV VPVSTSEFPR
PARRPANSVL DNLLLRVQGM DIMPHWRDSL RDHISEVAGR V
//
