ID A0BPY0_PARTE Unreviewed; 779 AA.
AC A0BPY0;
DT 28-NOV-2006, integrated into UniProtKB/TrEMBL.
DT 28-NOV-2006, sequence version 1.
DT 27-MAR-2024, entry version 80.
DE RecName: Full=histidine kinase {ECO:0000256|ARBA:ARBA00012438};
DE EC=2.7.13.3 {ECO:0000256|ARBA:ARBA00012438};
GN ORFNames=GSPATT00005348001 {ECO:0000313|EMBL:CAK60597.1};
OS Paramecium tetraurelia.
OC Eukaryota; Sar; Alveolata; Ciliophora; Intramacronucleata;
OC Oligohymenophorea; Peniculida; Parameciidae; Paramecium.
OX NCBI_TaxID=5888 {ECO:0000313|EMBL:CAK60597.1, ECO:0000313|Proteomes:UP000000600};
RN [1] {ECO:0000313|EMBL:CAK60597.1, ECO:0000313|Proteomes:UP000000600}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Stock d4-2 {ECO:0000313|EMBL:CAK60597.1,
RC ECO:0000313|Proteomes:UP000000600};
RX PubMed=17086204; DOI=10.1038/nature05230;
RG Genoscope;
RA Aury J.-M., Jaillon O., Duret L., Noel B., Jubin C., Porcel B.M.,
RA Segurens B., Daubin V., Anthouard V., Aiach N., Arnaiz O., Billaut A.,
RA Beisson J., Blanc I., Bouhouche K., Camara F., Duharcourt S., Guigo R.,
RA Gogendeau D., Katinka M., Keller A.-M., Kissmehl R., Klotz C., Koll F.,
RA Le Moue A., Lepere C., Malinsky S., Nowacki M., Nowak J.K., Plattner H.,
RA Poulain J., Ruiz F., Serrano V., Zagulski M., Dessen P., Betermier M.,
RA Weissenbach J., Scarpelli C., Schachter V., Sperling L., Meyer E.,
RA Cohen J., Wincker P.;
RT "Global trends of whole-genome duplications revealed by the ciliate
RT Paramecium tetraurelia.";
RL Nature 444:171-178(2006).
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DR EMBL; CT868008; CAK60597.1; -; Genomic_DNA.
DR RefSeq; XP_001427995.1; XM_001427958.1.
DR AlphaFoldDB; A0BPY0; -.
DR STRING; 5888.A0BPY0; -.
DR EnsemblProtists; CAK60597; CAK60597; GSPATT00005348001.
DR GeneID; 5013779; -.
DR KEGG; ptm:GSPATT00005348001; -.
DR eggNOG; KOG0519; Eukaryota.
DR HOGENOM; CLU_358824_0_0_1; -.
DR InParanoid; A0BPY0; -.
DR Proteomes; UP000000600; Partially assembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR CDD; cd00082; HisKA; 1.
DR CDD; cd17546; REC_hyHK_CKI1_RcsC-like; 1.
DR Gene3D; 1.10.287.130; -; 1.
DR Gene3D; 3.40.50.2300; -; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR InterPro; IPR011006; CheY-like_superfamily.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR005467; His_kinase_dom.
DR InterPro; IPR003661; HisK_dim/P.
DR InterPro; IPR036097; HisK_dim/P_sf.
DR InterPro; IPR004358; Sig_transdc_His_kin-like_C.
DR InterPro; IPR001789; Sig_transdc_resp-reg_receiver.
DR PANTHER; PTHR43719:SF28; PEROXIDE STRESS-ACTIVATED HISTIDINE KINASE MAK2; 1.
DR PANTHER; PTHR43719; TWO-COMPONENT HISTIDINE KINASE; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF00512; HisKA; 1.
DR Pfam; PF00072; Response_reg; 1.
DR PRINTS; PR00344; BCTRLSENSOR.
DR SMART; SM00387; HATPase_c; 1.
DR SMART; SM00388; HisKA; 1.
DR SMART; SM00448; REC; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF52172; CheY-like; 1.
DR SUPFAM; SSF47384; Homodimeric domain of signal transducing histidine kinase; 1.
DR PROSITE; PS50109; HIS_KIN; 1.
DR PROSITE; PS50110; RESPONSE_REGULATORY; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553, ECO:0000256|PROSITE-
KW ProRule:PRU00169}; Reference proteome {ECO:0000313|Proteomes:UP000000600};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 12..31
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 37..57
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 64..84
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 309..535
FT /note="Histidine kinase"
FT /evidence="ECO:0000259|PROSITE:PS50109"
FT DOMAIN 645..765
FT /note="Response regulatory"
FT /evidence="ECO:0000259|PROSITE:PS50110"
FT MOD_RES 699
FT /note="4-aspartylphosphate"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00169"
SQ SEQUENCE 779 AA; 89266 MW; B4EDC3D57F6CA5C1 CRC64;
MLALCKALNK ERILQFFLII DGLIVHMQTY VTQDFSFLVI GLTLACFHLI ILCFEYMCQK
KSNLILLICL IKGVVIIGVS YLLMPQWQIY TGIQIVLIIQ LNEQYLKLTT LFFFLACIPC
ICFGNVSEIT VEILRAVVNF FLILQIYKKK GNQSFINIKS LLSQISSEEF CILDMQYNPV
YESKLFYSII KEQVMNISDH YQSRILTPRD QTTNLVKQSN CLENITTRPS LLIGDIIDQL
KKKILKLDQK LIFEPTNTSL YQVSVQKLLI ENQEFILLIK HKLYNIESFK LQSQQQKEQV
QTMIKTLHKV SHDMRNPLNA IINMQMCLSE LIDPNLFQKF LKPSLNSCHL LLNLINDILD
AAQIENKSIR IVCRKFNLAK LIDKTISLFD LLKEKKGLNI TFNYDPKLPL KINSDKLRIR
QIIMNLLSNA VKYTQPKGSI LIECIQSEQK SNSIIISVQD SGMGIKSENL KKLFQEFSKV
NDLENQKANP FGIGLGLMIS NELAKLLSTN HSIGIQVQSE YGTGSKFYFE IENEEQPSED
ISDSQISQKL AQKIPTLEFR ILQNIIQQKS PTVSIAIPMG ESSKRIIQKK NLKAINFMTS
SLNYQATLRI RNESERNLSN KPSIQSRLIQ NLLQKWNELT QQHPPILIVD DNEFNILALQ
YLLELSGISS DSAMNGIISI EKVNDRLKDN IPFQLIFMDL EMPLMLGLEA STRIHKLDRN
VTIVACSGHK LTQEIVEQFK DCGIAFGVEK PITKIKLKDL LLKLSDGIRC DSSQFSQLF
//
