ID A0D3M1_PARTE Unreviewed; 1795 AA.
AC A0D3M1;
DT 28-NOV-2006, integrated into UniProtKB/TrEMBL.
DT 28-NOV-2006, sequence version 1.
DT 24-JAN-2024, entry version 81.
DE SubName: Full=Chromosome undetermined scaffold_36, whole genome shotgun sequence {ECO:0000313|EMBL:CAK77638.1};
GN ORFNames=GSPATT00013126001 {ECO:0000313|EMBL:CAK77638.1};
OS Paramecium tetraurelia.
OC Eukaryota; Sar; Alveolata; Ciliophora; Intramacronucleata;
OC Oligohymenophorea; Peniculida; Parameciidae; Paramecium.
OX NCBI_TaxID=5888 {ECO:0000313|EMBL:CAK77638.1, ECO:0000313|Proteomes:UP000000600};
RN [1] {ECO:0000313|EMBL:CAK77638.1, ECO:0000313|Proteomes:UP000000600}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Stock d4-2 {ECO:0000313|EMBL:CAK77638.1,
RC ECO:0000313|Proteomes:UP000000600};
RX PubMed=17086204; DOI=10.1038/nature05230;
RG Genoscope;
RA Aury J.-M., Jaillon O., Duret L., Noel B., Jubin C., Porcel B.M.,
RA Segurens B., Daubin V., Anthouard V., Aiach N., Arnaiz O., Billaut A.,
RA Beisson J., Blanc I., Bouhouche K., Camara F., Duharcourt S., Guigo R.,
RA Gogendeau D., Katinka M., Keller A.-M., Kissmehl R., Klotz C., Koll F.,
RA Le Moue A., Lepere C., Malinsky S., Nowacki M., Nowak J.K., Plattner H.,
RA Poulain J., Ruiz F., Serrano V., Zagulski M., Dessen P., Betermier M.,
RA Weissenbach J., Scarpelli C., Schachter V., Sperling L., Meyer E.,
RA Cohen J., Wincker P.;
RT "Global trends of whole-genome duplications revealed by the ciliate
RT Paramecium tetraurelia.";
RL Nature 444:171-178(2006).
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CT868274; CAK77638.1; -; Genomic_DNA.
DR RefSeq; XP_001445035.1; XM_001444998.1.
DR STRING; 5888.A0D3M1; -.
DR EnsemblProtists; CAK77638; CAK77638; GSPATT00013126001.
DR GeneID; 5030820; -.
DR KEGG; ptm:GSPATT00013126001; -.
DR eggNOG; ENOG502QPPT; Eukaryota.
DR HOGENOM; CLU_002334_0_0_1; -.
DR InParanoid; A0D3M1; -.
DR Proteomes; UP000000600; Partially assembled WGS sequence.
DR GO; GO:0009190; P:cyclic nucleotide biosynthetic process; IEA:InterPro.
DR GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR CDD; cd07302; CHD; 2.
DR CDD; cd00821; PH; 1.
DR Gene3D; 3.30.70.1230; Nucleotide cyclase; 2.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR InterPro; IPR001054; A/G_cyclase.
DR InterPro; IPR029787; Nucleotide_cyclase.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR001849; PH_domain.
DR PANTHER; PTHR47455; ADENYLYL CYCLASE BETA; 1.
DR PANTHER; PTHR47455:SF1; GUANYLATE CYCLASE DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF00211; Guanylate_cyc; 2.
DR Pfam; PF00169; PH; 1.
DR SMART; SM00044; CYCc; 1.
DR SMART; SM00233; PH; 1.
DR SUPFAM; SSF55073; Nucleotide cyclase; 2.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF50729; PH domain-like; 1.
DR PROSITE; PS50125; GUANYLATE_CYCLASE_2; 2.
DR PROSITE; PS50003; PH_DOMAIN; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000000600}.
FT DOMAIN 45..187
FT /note="Guanylate cyclase"
FT /evidence="ECO:0000259|PROSITE:PS50125"
FT DOMAIN 284..409
FT /note="Guanylate cyclase"
FT /evidence="ECO:0000259|PROSITE:PS50125"
FT DOMAIN 1123..1231
FT /note="PH"
FT /evidence="ECO:0000259|PROSITE:PS50003"
FT REGION 1456..1475
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1551..1576
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1612..1645
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1769..1795
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1795 AA; 206796 MW; E278C3F28BFB3FEB CRC64;
MSQQFQSQSM SILGYVPALV VQHLLNLKMN KLLRKLPEKQ RIRSVVMFAD ISGFTRLTEL
LSQLGTEGAE RIAFAINRYM ELLVQGIGRS GGDIFKFAGD AMIVIWPPPP NDQNFQQNLE
TLLKQAIQSA LLIQEKLTKA QIEQGIQLSV KIGFGVGEMN IIHVGGVFNR MEYLATGDPL
IQAFHSEHCL TEGGKIIISQ QIYDMINNFF ECQKVVDHEG HYEVIKLQQA KVKMKADALL
IKNNITLSQF QMIRNEIQSY IPAALLPYID INEEAWSAEL RRLSIMFVNL KMDLNSAKNA
QGLEQIQRVI KTVQKCIYMH EGSLNKLLMD DKGSTLIVVF GLPPLSHQND PVRAILTAQL
MNKELPKINC GCSIGIVTGT VFAGVVGTSG SRREYSVLGD SVNLAARLMQ AACSETTHKI
LMCLETAKSA GNCISTAFLR QTQVKGKNAP VHIYVPLDKL VEPTQGNLLP NFKTHNYAYG
FAKKSDFIAV QLFGREEQHK KLLNQIDKVI KGVDKKSLII LKGTYGCGKS ILAKKVLHRV
QEKINSNQYS PWKYGEYPHL LVQQLDPITR TFKLNGLRSI LKQIFLLYAK RVEKPPNMEL
FNMMVDVNIH PQNMILMLQE IVGLNDNRHL EKFPARQQEE DKEIEIKRIV FQFLSNFFEQ
IPSKFSELYE GRSPDQIGWD VMKSSVQRQI NYSIKYTNII APVVLCLDDI QNYDQISFQI
LRQMVKTYDR LTILALYRDS FQEMIIQPKV AEKRKSQEDI AIEGITALED RMDGNPFILM
QLRGVERKGG VDDEFAKMIR FSFNIQKFTP EQECRQSIGE GSIRKRNTSS IHDVVIQENQ
SREINNQFLF CENKQKLIKT DVELLFMQWI YMKTGGNPLM VLNFVQNLID LDLIRLSPKN
ATITNELVNL INYEESIIVD APYCRIEVNG PIIDKLSCLE QLLLKSASVI GDIFDIQLLN
KTYPFKNAVN NKLQKFLDEL EAKEVIEVME VREQNIFYRF TCPFMRDCLY QRITFKQRRQ
LHKAVAEAIQ QLPLPFETEE LVECKKLQFQ WLMAESNAYQ QINFENNDDN KSNSKPNFLV
NLINPKCTQD TQKFQNMSSK ALKSIILKQI GNKFNRSQNH ANIILRGGVL IKKSKNRVSS
VPRYVILDGK ELKLYQNRQD SLNCELPLCS IPLKSIYSVM ALESEKNFTL QIGSTYWYKN
LKEMGDRKFL FDAKDNEDLQ LWTIYLEFAK ALAIYEDFTN NYGKICFPIS NQYEQYDSQF
KYDIRIENKS IRGIQIEKTQ KNNKESIIQR NSRRSNRHSK FTVSSKQFKF MEKNSTDELQ
IQSAQVVDMQ LLKERVNLFL QKGILLLFSH LFEQSIQKAD DFKILGNTSI AMRKLNNVFK
IDKQLINEHN KKSSAFLQQQ QIMMEDKQET KLQDNWEIVI QKVEMDNDLT NNQNLNQMLE
EKIEKTDMIF ELERKSSQDQ EKLSELENDD QTPKLNLQVK SFKDLKENID EEEVDNFQLD
ESALRKQQHL RIQRLQNFKG SFGNDSFQKM HSESVLRSSP LMKQEDTLTE VLATQSQTEN
SKRESTDLYQ STQQPPQLLT KISEKESITD ASCQVSRHLS ICQVDKIIPV SNNQRSRQTS
NINNQQNRSP PHTQKSLTPT NHSQKNTQFN LLDECKSKAK RDSQLSSQLN SGRNKPAHLL
TNYINSQKTF SKQNNIVYGT AINNCKPITG DNFILKPGYK VIVQRIDKQA QLIECLYENL
IGIFRLRDIA VIEDPTIEQK IEITSLLSKQ PSKSPLKKQL QSNRPKPFLT PTKKN
//
