ID A0D7V4_PARTE Unreviewed; 862 AA.
AC A0D7V4;
DT 28-NOV-2006, integrated into UniProtKB/TrEMBL.
DT 28-NOV-2006, sequence version 1.
DT 27-MAR-2024, entry version 80.
DE RecName: Full=histidine kinase {ECO:0000256|ARBA:ARBA00012438};
DE EC=2.7.13.3 {ECO:0000256|ARBA:ARBA00012438};
GN ORFNames=GSPATT00014088001 {ECO:0000313|EMBL:CAK79121.1};
OS Paramecium tetraurelia.
OC Eukaryota; Sar; Alveolata; Ciliophora; Intramacronucleata;
OC Oligohymenophorea; Peniculida; Parameciidae; Paramecium.
OX NCBI_TaxID=5888 {ECO:0000313|EMBL:CAK79121.1, ECO:0000313|Proteomes:UP000000600};
RN [1] {ECO:0000313|EMBL:CAK79121.1, ECO:0000313|Proteomes:UP000000600}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Stock d4-2 {ECO:0000313|EMBL:CAK79121.1,
RC ECO:0000313|Proteomes:UP000000600};
RX PubMed=17086204; DOI=10.1038/nature05230;
RG Genoscope;
RA Aury J.-M., Jaillon O., Duret L., Noel B., Jubin C., Porcel B.M.,
RA Segurens B., Daubin V., Anthouard V., Aiach N., Arnaiz O., Billaut A.,
RA Beisson J., Blanc I., Bouhouche K., Camara F., Duharcourt S., Guigo R.,
RA Gogendeau D., Katinka M., Keller A.-M., Kissmehl R., Klotz C., Koll F.,
RA Le Moue A., Lepere C., Malinsky S., Nowacki M., Nowak J.K., Plattner H.,
RA Poulain J., Ruiz F., Serrano V., Zagulski M., Dessen P., Betermier M.,
RA Weissenbach J., Scarpelli C., Schachter V., Sperling L., Meyer E.,
RA Cohen J., Wincker P.;
RT "Global trends of whole-genome duplications revealed by the ciliate
RT Paramecium tetraurelia.";
RL Nature 444:171-178(2006).
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DR EMBL; CT868319; CAK79121.1; -; Genomic_DNA.
DR RefSeq; XP_001446518.1; XM_001446481.1.
DR AlphaFoldDB; A0D7V4; -.
DR STRING; 5888.A0D7V4; -.
DR EnsemblProtists; CAK79121; CAK79121; GSPATT00014088001.
DR GeneID; 5032303; -.
DR KEGG; ptm:GSPATT00014088001; -.
DR eggNOG; KOG0519; Eukaryota.
DR HOGENOM; CLU_016833_0_0_1; -.
DR InParanoid; A0D7V4; -.
DR Proteomes; UP000000600; Partially assembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR CDD; cd00082; HisKA; 1.
DR CDD; cd17546; REC_hyHK_CKI1_RcsC-like; 1.
DR Gene3D; 1.10.287.130; -; 1.
DR Gene3D; 3.40.50.2300; -; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR InterPro; IPR011006; CheY-like_superfamily.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR005467; His_kinase_dom.
DR InterPro; IPR003661; HisK_dim/P.
DR InterPro; IPR036097; HisK_dim/P_sf.
DR InterPro; IPR004358; Sig_transdc_His_kin-like_C.
DR InterPro; IPR001789; Sig_transdc_resp-reg_receiver.
DR PANTHER; PTHR43719:SF28; PEROXIDE STRESS-ACTIVATED HISTIDINE KINASE MAK2; 1.
DR PANTHER; PTHR43719; TWO-COMPONENT HISTIDINE KINASE; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF00072; Response_reg; 1.
DR PRINTS; PR00344; BCTRLSENSOR.
DR SMART; SM00387; HATPase_c; 1.
DR SMART; SM00448; REC; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF52172; CheY-like; 1.
DR SUPFAM; SSF47384; Homodimeric domain of signal transducing histidine kinase; 1.
DR PROSITE; PS50109; HIS_KIN; 1.
DR PROSITE; PS50110; RESPONSE_REGULATORY; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553, ECO:0000256|PROSITE-
KW ProRule:PRU00169}; Reference proteome {ECO:0000313|Proteomes:UP000000600};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 7..26
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 32..50
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 432..675
FT /note="Histidine kinase"
FT /evidence="ECO:0000259|PROSITE:PS50109"
FT DOMAIN 729..862
FT /note="Response regulatory"
FT /evidence="ECO:0000259|PROSITE:PS50110"
FT MOD_RES 793
FT /note="4-aspartylphosphate"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00169"
SQ SEQUENCE 862 AA; 100248 MW; 64A8521724B0E8BF CRC64;
MNQYERVFKE SWIMIIITLL IMFQSIFGDG SLIITIIILG IQILCVMMGF ISQTQKYSIH
FEMFQQWTLL FALYISSKSN AMSILALCSL KEFFICKINT QLPSLNKYQI IHQIGSDLLL
FIIILLEDYN QVYLSATTIM VHWLILFHIS KAKLVTKHTI SSTQQEINDK IMIDSVGNTQ
NHSRLKFKEK PSHNESPTIE RDNRLEILSI FPQGIGLIKI TDKKIELEYH NENLLKLSMA
EQSDQILSSL FCLEQQSIQE DQQKQQNDYK NSMSSFSTFQ QTPIPCNLIS KASRNEKRSQ
TNKLQSSHKL ELFRQNSALS NIEYKGVILR KCDTLEESIL EQELRLISSQ MRKVDFQNYM
KNQNQLIQEH VVILGYQKGQ DGKKNRTIEV KLYNALIVDV PYILMLIRDI THRDYIHQLR
DYSKQKSKTL SFVSHEYRTP LNCIIDMLEQ EVDDDQKYSS QTMIMEKDIR RSTKQNNPIK
MAKQIKIALD HAKYLQNLSD DLLDLAQIKV GKFKINKAKF NFNQLLETCV DLFQVMAERK
QIKLYINYES KAPRYICSDP SRLKQIMINL LGNAFKFTED GSVTIKVAQV NLRLEISVVD
TGIGMTEEDQ LRIFQAFGKG NSEEHKKMNK SGVGLGLLIS NQILQNLNQD LQNGLKFKSQ
YKKGSTFYFQ IQYQDINEIK SLNSMEERNQ DSEESIIMQQ QQEESIHKVY VNNQASIFKR
STKAIMTTQI MIVDDVCMNI DMLKRRLAQM QYKIIIIRGQ DHIDSATNGY LAIEKCSKKW
QANQDYYKLI FMDLEMPTIN GIQTTKKILE LSQKYGIDVK IIGCSAYESL EQKQECLNAG
MKDYITKPIQ LQDLNRIVQQ YL
//
