ID A0E888_PARTE Unreviewed; 664 AA.
AC A0E888;
DT 28-NOV-2006, integrated into UniProtKB/TrEMBL.
DT 28-NOV-2006, sequence version 1.
DT 27-MAR-2024, entry version 90.
DE SubName: Full=Chromosome undetermined scaffold_82, whole genome shotgun sequence {ECO:0000313|EMBL:CAK91505.1};
GN ORFNames=GSPATT00024233001 {ECO:0000313|EMBL:CAK91505.1};
OS Paramecium tetraurelia.
OC Eukaryota; Sar; Alveolata; Ciliophora; Intramacronucleata;
OC Oligohymenophorea; Peniculida; Parameciidae; Paramecium.
OX NCBI_TaxID=5888 {ECO:0000313|EMBL:CAK91505.1, ECO:0000313|Proteomes:UP000000600};
RN [1] {ECO:0000313|EMBL:CAK91505.1, ECO:0000313|Proteomes:UP000000600}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Stock d4-2 {ECO:0000313|EMBL:CAK91505.1,
RC ECO:0000313|Proteomes:UP000000600};
RX PubMed=17086204; DOI=10.1038/nature05230;
RG Genoscope;
RA Aury J.-M., Jaillon O., Duret L., Noel B., Jubin C., Porcel B.M.,
RA Segurens B., Daubin V., Anthouard V., Aiach N., Arnaiz O., Billaut A.,
RA Beisson J., Blanc I., Bouhouche K., Camara F., Duharcourt S., Guigo R.,
RA Gogendeau D., Katinka M., Keller A.-M., Kissmehl R., Klotz C., Koll F.,
RA Le Moue A., Lepere C., Malinsky S., Nowacki M., Nowak J.K., Plattner H.,
RA Poulain J., Ruiz F., Serrano V., Zagulski M., Dessen P., Betermier M.,
RA Weissenbach J., Scarpelli C., Schachter V., Sperling L., Meyer E.,
RA Cohen J., Wincker P.;
RT "Global trends of whole-genome duplications revealed by the ciliate
RT Paramecium tetraurelia.";
RL Nature 444:171-178(2006).
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DR EMBL; CT868663; CAK91505.1; -; Genomic_DNA.
DR RefSeq; XP_001458902.1; XM_001458865.1.
DR AlphaFoldDB; A0E888; -.
DR STRING; 5888.A0E888; -.
DR EnsemblProtists; CAK91505; CAK91505; GSPATT00024233001.
DR GeneID; 5044687; -.
DR KEGG; ptm:GSPATT00024233001; -.
DR eggNOG; KOG0603; Eukaryota.
DR HOGENOM; CLU_413614_0_0_1; -.
DR InParanoid; A0E888; -.
DR Proteomes; UP000000600; Partially assembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR CDD; cd05123; STKc_AGC; 1.
DR Gene3D; 1.25.40.20; Ankyrin repeat-containing domain; 1.
DR Gene3D; 1.10.510.10; Transferase(Phosphotransferase) domain 1; 1.
DR InterPro; IPR002110; Ankyrin_rpt.
DR InterPro; IPR036770; Ankyrin_rpt-contain_sf.
DR InterPro; IPR011009; Kinase-like_dom_sf.
DR InterPro; IPR000719; Prot_kinase_dom.
DR InterPro; IPR017441; Protein_kinase_ATP_BS.
DR InterPro; IPR045270; STKc_AGC.
DR PANTHER; PTHR24351; RIBOSOMAL PROTEIN S6 KINASE; 1.
DR PANTHER; PTHR24351:SF243; RIBOSOMAL PROTEIN S6 KINASE; 1.
DR Pfam; PF00023; Ank; 1.
DR Pfam; PF12796; Ank_2; 1.
DR Pfam; PF00069; Pkinase; 1.
DR SMART; SM00248; ANK; 3.
DR SMART; SM00220; S_TKc; 1.
DR SUPFAM; SSF48403; Ankyrin repeat; 1.
DR SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
DR PROSITE; PS50297; ANK_REP_REGION; 2.
DR PROSITE; PS50088; ANK_REPEAT; 2.
DR PROSITE; PS00107; PROTEIN_KINASE_ATP; 1.
DR PROSITE; PS50011; PROTEIN_KINASE_DOM; 1.
PE 4: Predicted;
KW ANK repeat {ECO:0000256|PROSITE-ProRule:PRU00023};
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW ProRule:PRU10141}; Kinase {ECO:0000256|ARBA:ARBA00022777};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW ProRule:PRU10141}; Reference proteome {ECO:0000313|Proteomes:UP000000600};
KW Serine/threonine-protein kinase {ECO:0000256|ARBA:ARBA00022527};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT REPEAT 198..230
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 231..263
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT DOMAIN 351..609
FT /note="Protein kinase"
FT /evidence="ECO:0000259|PROSITE:PS50011"
FT BINDING 380
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU10141"
SQ SEQUENCE 664 AA; 76093 MW; A393445006A2555D CRC64;
MLAIFQLEIY MINFLNVKQQ SCDLYDSGQV LRFDQKNYLK QSNTMNVQQV PITKPPSRSP
MQTYNIAKII KTEPSQSDRQ FSAGHRCERS MLSPSLLDEG SVLVQKLPPN KLVINLNIKV
KASGKYPEFC IRDQDTGKVI DIRFQDWRNN WFLYFQSIRN TKSPNNAKLI KAVKNNSYNE
VKEILLKDKP DINARDTDGN TVLHLSVMSG NSKLVGLLLY HEAQIDSLNS KLQTPLMIAC
SLGIEEITQQ LITAGADINS QDINKNTCLH LATMNERQKI MDLLLNKQSL NMTLKNKENK
IAMDYSSNQQ MFLQAMQKQN NNSIKIYDAR TDFGSENCNS FNEDKVGPHH FKVHALIGKG
SFGEVYLVEK LDTNQLLAMK VLHKSKIQKQ NLTRYALTER NVLSLTKHPF IVRLRYAFQT
ADKLCLIMDY CPGGDLSSHL RREQRFPEER VKLYLTQMIL ALEDLHKRDI IFRDLKPDNI
VLDADGYAML TDFGLSKEGV QEHYTGARSF CGSVAYLAPE MLKRCGHGKA VDWYLLGVVM
YELLVGQPPY YANDREELFN NIQKADLKLP TYISHDGINL LKALLQRNPA KRLGSGKGDA
EEIKAHPYFK DIEWGKVKDK EIKMPILSRK TRFIKVEHNV FEIGSFLEQS HLAGWSFAEH
KIQQ
//
