ID A0KGM2_AERHH Unreviewed; 540 AA.
AC A0KGM2;
DT 12-DEC-2006, integrated into UniProtKB/TrEMBL.
DT 12-DEC-2006, sequence version 1.
DT 27-MAR-2024, entry version 100.
DE RecName: Full=Thiamine transport system permease protein ThiP {ECO:0000256|ARBA:ARBA00016947};
GN Name=thiP {ECO:0000313|EMBL:ABK37028.1};
GN OrderedLocusNames=AHA_0875 {ECO:0000313|EMBL:ABK37028.1};
OS Aeromonas hydrophila subsp. hydrophila (strain ATCC 7966 / DSM 30187 / BCRC
OS 13018 / CCUG 14551 / JCM 1027 / KCTC 2358 / NCIMB 9240 / NCTC 8049).
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Aeromonadales;
OC Aeromonadaceae; Aeromonas.
OX NCBI_TaxID=380703 {ECO:0000313|EMBL:ABK37028.1, ECO:0000313|Proteomes:UP000000756};
RN [1] {ECO:0000313|EMBL:ABK37028.1, ECO:0000313|Proteomes:UP000000756}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 7966 / DSM 30187 / BCRC 13018 / CCUG 14551 / JCM 1027 /
RC KCTC 2358 / NCIMB 9240 / NCTC 8049
RC {ECO:0000313|Proteomes:UP000000756};
RX PubMed=16980456; DOI=10.1128/JB.00621-06;
RA Seshadri R., Joseph S.W., Chopra A.K., Sha J., Shaw J., Graf J., Haft D.,
RA Wu M., Ren Q., Rosovitz M.J., Madupu R., Tallon L., Kim M., Jin S.,
RA Vuong H., Stine O.C., Ali A., Horneman A.J., Heidelberg J.F.;
RT "Genome sequence of Aeromonas hydrophila ATCC 7966T: jack of all trades.";
RL J. Bacteriol. 188:8272-8282(2006).
CC -!- SUBUNIT: The complex is composed of two ATP-binding proteins (ThiQ),
CC two transmembrane proteins (ThiP) and a solute-binding protein (ThiB).
CC {ECO:0000256|ARBA:ARBA00011650}.
CC -!- SUBCELLULAR LOCATION: Cell inner membrane
CC {ECO:0000256|ARBA:ARBA00004429}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004429}. Cell membrane
CC {ECO:0000256|RuleBase:RU363032}; Multi-pass membrane protein
CC {ECO:0000256|RuleBase:RU363032}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the binding-protein-dependent transport system
CC permease family. {ECO:0000256|RuleBase:RU363032}.
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DR EMBL; CP000462; ABK37028.1; -; Genomic_DNA.
DR RefSeq; WP_011704815.1; NC_008570.1.
DR RefSeq; YP_855414.1; NC_008570.1.
DR AlphaFoldDB; A0KGM2; -.
DR STRING; 380703.AHA_0875; -.
DR EnsemblBacteria; ABK37028; ABK37028; AHA_0875.
DR KEGG; aha:AHA_0875; -.
DR PATRIC; fig|380703.7.peg.875; -.
DR eggNOG; COG1178; Bacteria.
DR HOGENOM; CLU_021838_5_3_6; -.
DR OrthoDB; 7066776at2; -.
DR Proteomes; UP000000756; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR GO; GO:0015888; P:thiamine transport; IEA:InterPro.
DR CDD; cd06261; TM_PBP2; 2.
DR Gene3D; 1.10.3720.10; MetI-like; 2.
DR InterPro; IPR000515; MetI-like.
DR InterPro; IPR035906; MetI-like_sf.
DR InterPro; IPR005947; ThiP_ABC_transpt.
DR NCBIfam; TIGR01253; thiP; 1.
DR PANTHER; PTHR30183; MOLYBDENUM TRANSPORT SYSTEM PERMEASE PROTEIN MODB; 1.
DR PANTHER; PTHR30183:SF9; THIAMINE TRANSPORT SYSTEM PERMEASE PROTEIN THIP; 1.
DR Pfam; PF00528; BPD_transp_1; 1.
DR SUPFAM; SSF161098; MetI-like; 2.
DR PROSITE; PS50928; ABC_TM1; 2.
PE 3: Inferred from homology;
KW Cell inner membrane {ECO:0000256|ARBA:ARBA00022519};
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU363032};
KW Reference proteome {ECO:0000313|Proteomes:UP000000756};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU363032};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|RuleBase:RU363032}; Transport {ECO:0000256|RuleBase:RU363032}.
FT TRANSMEM 60..81
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363032"
FT TRANSMEM 93..117
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363032"
FT TRANSMEM 137..161
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363032"
FT TRANSMEM 201..222
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363032"
FT TRANSMEM 242..262
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363032"
FT TRANSMEM 292..317
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363032"
FT TRANSMEM 337..358
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363032"
FT TRANSMEM 379..401
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363032"
FT TRANSMEM 407..425
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363032"
FT TRANSMEM 469..488
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363032"
FT TRANSMEM 508..529
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363032"
FT DOMAIN 58..261
FT /note="ABC transmembrane type-1"
FT /evidence="ECO:0000259|PROSITE:PS50928"
FT DOMAIN 334..529
FT /note="ABC transmembrane type-1"
FT /evidence="ECO:0000259|PROSITE:PS50928"
SQ SEQUENCE 540 AA; 58412 MW; 604C5689B052B3B5 CRC64;
MSRIFARAQA RPLWWLPGSA ATLIILLLSL GPLAALLWQA GSLAPRTLLA DPYLRHVLGF
SLWQALLSTL LSLGLAIPVA RALARRRFIG RRLLLKLFGL SLVLPVIIAI FGIVAVHGKQ
GWLPQLLHGL GLAPGNYLYG LLGILLAHVF FNMPLAARLL LQSIESIPES SWRLASQLGM
RSSHIFRLLE WPLIRAQLPG LASLIFMLCF TSFTTVLALG GGPKSTTLEV AVYQALRFDF
DLATAGGLAL VQLILTAGLL MLQHKLQSSP ASRISARRPC LRPDRHQPGT GLVDTLALGI
GLAVFLPPLL AIVVAGLNPG LLGALTSSKL WLASGQSLLI ALAAGTLATL LGSALLLTSR
HLRVRDRKRR AAALWEASGS VILMIPAVVL STGLFILFMP FADVFALGPW LVVLVNALMA
LPYVLRTLSA PMQLVVRQYD RLADSLGVRG LHRLRLVEWP LLRRPLAQAA ALSMILSLGD
LGAIAMFGSQ ELTTLPWLLY QQLGSYRLTE AAATALLLLI LCFSLFWLIE RGLGGKHADH
//
