ID   A0P826_9PROT            Unreviewed;       355 AA.
AC   A0P826;
DT   03-OCT-2012, integrated into UniProtKB/TrEMBL.
DT   03-OCT-2012, sequence version 1.
DT   13-SEP-2023, entry version 36.
DE   SubName: Full=Aldo/keto reductase {ECO:0000313|EMBL:EAV47686.1};
GN   ORFNames=MB2181_06395 {ECO:0000313|EMBL:EAV47686.1};
OS   Methylophilales bacterium HTCC2181.
OC   Bacteria; Pseudomonadota; Betaproteobacteria; Nitrosomonadales; OM43 clade.
OX   NCBI_TaxID=383631 {ECO:0000313|EMBL:EAV47686.1, ECO:0000313|Proteomes:UP000054262};
RN   [1] {ECO:0000313|EMBL:EAV47686.1, ECO:0000313|Proteomes:UP000054262}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=HTCC2181 {ECO:0000313|EMBL:EAV47686.1,
RC   ECO:0000313|Proteomes:UP000054262};
RA   Giovannoni S., Vergin K., Ferriera S., Johnson J., Kravitz S., Beeson K.,
RA   Sutton G., Rogers Y.-H., Friedman R., Frazier M., Venter J.C.;
RL   Submitted (NOV-2006) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EAV47686.1}.
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DR   EMBL; AAUX01000001; EAV47686.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0P826; -.
DR   OrthoDB; 5488419at2; -.
DR   Proteomes; UP000054262; Unassembled WGS sequence.
DR   CDD; cd19094; AKR_Tas-like; 1.
DR   Gene3D; 3.20.20.100; NADP-dependent oxidoreductase domain; 1.
DR   InterPro; IPR023210; NADP_OxRdtase_dom.
DR   InterPro; IPR036812; NADP_OxRdtase_dom_sf.
DR   PANTHER; PTHR43364:SF4; NAD(P)-LINKED OXIDOREDUCTASE SUPERFAMILY PROTEIN; 1.
DR   PANTHER; PTHR43364; NADH-SPECIFIC METHYLGLYOXAL REDUCTASE-RELATED; 1.
DR   Pfam; PF00248; Aldo_ket_red; 1.
DR   SUPFAM; SSF51430; NAD(P)-linked oxidoreductase; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000054262}.
FT   DOMAIN          19..346
FT                   /note="NADP-dependent oxidoreductase"
FT                   /evidence="ECO:0000259|Pfam:PF00248"
SQ   SEQUENCE   355 AA;  40565 MW;  5763F6CAEC4A53EA CRC64;
     MFEKKDYRLV GNSSLLVSPI TLGTMTFGDQ NTQEEAFHQL DFAIDQGINC LDVAELYPVP
     PKADTYTKTE IIIGNWLKYQ KREELVLSTK VAGPRRDLSW IRGGPLSLDR KNIIESVEKS
     LQRLQTDYVD LLYLHWPERN VPMFGQYKFD PEMEYRDGKK INWVSIEEQL NTLSELVSSG
     KARFIALSNE WSWGVMEFIR IAREKGLPVI CNIQNNYSLL NRVAELGLTE IMYREGISFF
     PYSPLGFGHL TGKYLKNPEE KGRVNLFKGY AQRFDKPGVP KAVESYSALA ADMGVSPTSL
     ALSFVYHQWF VKSTVIGATS IEQLKENIEA YALRLDDSVL KRIDDIHLRC MNPAP
//