ID A0PCL5_XENLA Unreviewed; 569 AA.
AC A0PCL5;
DT 09-JAN-2007, integrated into UniProtKB/TrEMBL.
DT 09-JAN-2007, sequence version 1.
DT 27-MAR-2024, entry version 72.
DE SubName: Full=Chromatin assembly factor 1 {ECO:0000313|EMBL:CAE18107.1};
DE SubName: Full=Chromatin assembly factor-1 p60 subunit isoform X1 {ECO:0000313|RefSeq:XP_018100852.1};
GN Name=chaf1b.L {ECO:0000313|RefSeq:XP_018100852.1,
GN ECO:0000313|Xenbase:XB-GENE-996582};
GN Synonyms=caf-1 {ECO:0000313|RefSeq:XP_018100852.1}, chaf1b
GN {ECO:0000313|RefSeq:XP_018100852.1}, p60
GN {ECO:0000313|EMBL:CAE18107.1};
OS Xenopus laevis (African clawed frog).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus.
OX NCBI_TaxID=8355 {ECO:0000313|EMBL:CAE18107.1};
RN [1] {ECO:0000313|EMBL:CAE18107.1}
RP NUCLEOTIDE SEQUENCE.
RA Ray-Gallet D.;
RL Submitted (JUL-2003) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:CAE18107.1}
RP NUCLEOTIDE SEQUENCE.
RA Quivy J.P.;
RL Submitted (NOV-2006) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|RefSeq:XP_018100852.1}
RP IDENTIFICATION.
RC STRAIN=J_2021 {ECO:0000313|RefSeq:XP_018100852.1};
RC TISSUE=Erythrocytes {ECO:0000313|RefSeq:XP_018100852.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR EMBL; AJ579309; CAE18107.1; -; mRNA.
DR RefSeq; XP_018100852.1; XM_018245363.2.
DR STRING; 8355.A0PCL5; -.
DR PaxDb; 8355-A0PCL5; -.
DR GeneID; 779086; -.
DR AGR; Xenbase:XB-GENE-996582; -.
DR CTD; 779086; -.
DR Xenbase; XB-GENE-996582; chaf1b.L.
DR OMA; QIYWHES; -.
DR OrthoDB; 5478541at2759; -.
DR Proteomes; UP000186698; Chromosome 2L.
DR Bgee; 779086; Expressed in testis and 18 other cell types or tissues.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0006335; P:DNA replication-dependent chromatin assembly; IEA:InterPro.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 3.
DR InterPro; IPR029129; CAF1_p60_C.
DR InterPro; IPR001632; Gprotein_B.
DR InterPro; IPR045145; PTHR15271.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR InterPro; IPR019775; WD40_repeat_CS.
DR InterPro; IPR036322; WD40_repeat_dom_sf.
DR InterPro; IPR001680; WD40_rpt.
DR PANTHER; PTHR15271; CHROMATIN ASSEMBLY FACTOR 1 SUBUNIT B; 1.
DR PANTHER; PTHR15271:SF4; CHROMATIN ASSEMBLY FACTOR 1 SUBUNIT B; 1.
DR Pfam; PF15512; CAF-1_p60_C; 1.
DR Pfam; PF00400; WD40; 5.
DR PRINTS; PR00319; GPROTEINB.
DR SMART; SM00320; WD40; 5.
DR SUPFAM; SSF50978; WD40 repeat-like; 1.
DR PROSITE; PS00678; WD_REPEATS_1; 1.
DR PROSITE; PS50082; WD_REPEATS_2; 3.
DR PROSITE; PS50294; WD_REPEATS_REGION; 2.
PE 2: Evidence at transcript level;
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000186698};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW WD repeat {ECO:0000256|ARBA:ARBA00022574, ECO:0000256|PROSITE-
KW ProRule:PRU00221}.
FT REPEAT 61..102
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 124..165
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 166..207
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT DOMAIN 386..551
FT /note="Chromatin assembly factor 1 subunit B C-terminal"
FT /evidence="ECO:0000259|Pfam:PF15512"
FT REGION 400..569
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 413..471
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 487..525
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 539..553
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 554..569
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 569 AA; 62936 MW; B8CF950F5D10AF68 CRC64;
MKVITCEISW HNKEPVYSLD FQHGNDKFNR LASAGVDTAV RLWKIERSPE GKAVVEFLAS
LARHTKAVNV VRFSPNGEIL ASGGDDAAIL LWKLNETKEC EPAPFQEQDE FELNKENWTV
FKTLRGHLED VYDICWTQDS NFMVSASVDN TAITWDVTKG QKLSIFNEHK SYVQGVTWDP
LGQYIATLSC DRIMRVYKTE TKRVAYNVSK MTSSPGPDGE AKSFRMYHDD SMKSFFRRLT
FTPDGSLLLT PAGCVEAGET VINTTYVFGR KNLRRPIAHL PCPTKATLAV RCCPVYFELR
PTMKDDSGES RPQGLITQPY RMVFAVASED AVLFYDTQQL FPFGYVSNVH YHTLSDISWS
SDGNFLAISS TDGYCSFVTF EEGELGVPLK EKPVALIPKT PATERKIKKA QSKKVSSPGS
RQELTPSNKS MEHSAPSTPM NSRPTPASGS RECTPVSSNS LASTPNSEDK RNAKGGQPRR
IMLNTLEAWS KPTTPSPRRI SLISVKTNSP SSAPSSPALS TTPRPEANPS VPPSEDVGCK
PPESKRLRTE DSPSCSSSDK PSGSDQTNK
//
