ID A0PX00_MYCUA Unreviewed; 632 AA.
AC A0PX00;
DT 09-JAN-2007, integrated into UniProtKB/TrEMBL.
DT 09-JAN-2007, sequence version 1.
DT 27-MAR-2024, entry version 69.
DE SubName: Full=Bifunctional UDP-galactofuranosyl transferase GlfT {ECO:0000313|EMBL:ABL06869.1};
GN Name=glfT {ECO:0000313|EMBL:ABL06869.1};
GN OrderedLocusNames=MUL_4992 {ECO:0000313|EMBL:ABL06869.1};
OS Mycobacterium ulcerans (strain Agy99).
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Mycobacteriaceae;
OC Mycobacterium; Mycobacterium ulcerans group.
OX NCBI_TaxID=362242 {ECO:0000313|EMBL:ABL06869.1, ECO:0000313|Proteomes:UP000000765};
RN [1] {ECO:0000313|EMBL:ABL06869.1, ECO:0000313|Proteomes:UP000000765}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Agy99 {ECO:0000313|EMBL:ABL06869.1,
RC ECO:0000313|Proteomes:UP000000765};
RX PubMed=17210928; DOI=10.1101/gr.5942807;
RA Stinear T.P., Seemann T., Pidot S., Frigui W., Reysset G., Garnier T.,
RA Meurice G., Simon D., Bouchier C., Ma L., Tichit M., Porter J.L., Ryan J.,
RA Johnson P.D., Davies J.K., Jenkin G.A., Small P.L., Jones L.M., Tekaia F.,
RA Laval F., Daffe M., Parkhill J., Cole S.T.;
RT "Reductive evolution and niche adaptation inferred from the genome of
RT Mycobacterium ulcerans, the causative agent of Buruli ulcer.";
RL Genome Res. 17:192-200(2007).
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DR EMBL; CP000325; ABL06869.1; -; Genomic_DNA.
DR RefSeq; WP_011742460.1; NC_008611.1.
DR AlphaFoldDB; A0PX00; -.
DR CAZy; GT2; Glycosyltransferase Family 2.
DR GeneID; 72436637; -.
DR KEGG; mul:MUL_4992; -.
DR eggNOG; COG1216; Bacteria.
DR HOGENOM; CLU_019973_0_0_11; -.
DR Proteomes; UP000000765; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0016757; F:glycosyltransferase activity; IEA:UniProtKB-KW.
DR Gene3D; 3.90.550.60; -; 1.
DR InterPro; IPR045699; GlfT2_C.
DR InterPro; IPR040492; GlfT2_N.
DR InterPro; IPR029044; Nucleotide-diphossugar_trans.
DR PANTHER; PTHR43179; RHAMNOSYLTRANSFERASE WBBL; 1.
DR PANTHER; PTHR43179:SF7; RHAMNOSYLTRANSFERASE WBBL; 1.
DR Pfam; PF19320; GlfT2_domain3; 1.
DR Pfam; PF17994; Glft2_N; 1.
DR Pfam; PF13641; Glyco_tranf_2_3; 1.
DR SUPFAM; SSF53448; Nucleotide-diphospho-sugar transferases; 1.
PE 4: Predicted;
KW Transferase {ECO:0000313|EMBL:ABL06869.1}.
FT DOMAIN 7..150
FT /note="Galactofuranosyltransferase GlfT2 N-terminal"
FT /evidence="ECO:0000259|Pfam:PF17994"
FT DOMAIN 430..620
FT /note="Galactofuranosyltransferase-2 C-terminal"
FT /evidence="ECO:0000259|Pfam:PF19320"
SQ SEQUENCE 632 AA; 70804 MW; 53F3AEB3F2D35CE1 CRC64;
MSAVSLLSRV ILPRPGEPLD VRKLYLEEST TNARRACATS RTSLQIGPES EVSFATYFNA
FPASYWRRWS ICKSVVLRVE LSGAGRVDVY RTKATGARIF VEGRAFAGDE DKPAVLEIEV
ALTPFEDGGW IWFDITTDTA VTLLNAGWYA AEPAPGTANI AVGIPTFNRP ADCANALREL
TADPLVDEVV GAVIVPDQGT RKVRDHPDFP AAAARLGDRL SIHDQPNLGG SGGYSRVMYE
ALKNTDCQQI LFMDDDIRIE PDSILRVLAM HRFAKSPMLV GGQMLNLQEP SHLHIMGEVV
NRANFMWTAA SHAEYDHDFA EYPLNDNEDK SKLLHRRIDV DYNGWWTCMI PRQVAEELGQ
PLPLFIKWDD ADYGLRAAEH GYPTVTLPGA AVWHMAWSDK DDAIDWQAYF HLRNRLVVAA
MHWDGDVTGL VRSHLKATLK HLACLEYSTV EIQNKAIDDF LAGPEHIFSI LESALPEVHC
IRKSYPDAVV LPAASELPPP LHKNIVNKPP TNPVTIGYRL ARGILHNLKT ADPAHHGRPE
FNVPTQDARW FRLCTVDGVT VTTADGCGVV YRQRDRAKML SLLWQSLRRQ RELSKRFDEM
RRTYRNALPV LSSKQKWETA LLPATSHEPE HA
//
