ID A0PXN8_CLONN Unreviewed; 692 AA.
AC A0PXN8;
DT 09-JAN-2007, integrated into UniProtKB/TrEMBL.
DT 09-JAN-2007, sequence version 1.
DT 27-MAR-2024, entry version 109.
DE RecName: Full=Elongation factor G {ECO:0000256|ARBA:ARBA00017872};
GN Name=fusA {ECO:0000313|EMBL:ABK60531.1};
GN OrderedLocusNames=NT01CX_1056 {ECO:0000313|EMBL:ABK60531.1};
OS Clostridium novyi (strain NT).
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Clostridiaceae;
OC Clostridium.
OX NCBI_TaxID=386415 {ECO:0000313|EMBL:ABK60531.1, ECO:0000313|Proteomes:UP000008220};
RN [1] {ECO:0000313|EMBL:ABK60531.1, ECO:0000313|Proteomes:UP000008220}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NT {ECO:0000313|EMBL:ABK60531.1,
RC ECO:0000313|Proteomes:UP000008220};
RX PubMed=17115055; DOI=10.1038/nbt1256;
RA Bettegowda C., Huang X., Lin J., Cheong I., Kohli M., Szabo S.A., Zhang X.,
RA Diaz L.A. Jr., Velculescu V.E., Parmigiani G., Kinzler K.W., Vogelstein B.,
RA Zhou S.;
RT "The genome and transcriptomes of the anti-tumor agent Clostridium novyi-
RT NT.";
RL Nat. Biotechnol. 24:1573-1580(2006).
CC -!- SIMILARITY: Belongs to the TRAFAC class translation factor GTPase
CC superfamily. Classic translation factor GTPase family. EF-G/EF-2
CC subfamily. {ECO:0000256|ARBA:ARBA00005870}.
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DR EMBL; CP000382; ABK60531.1; -; Genomic_DNA.
DR RefSeq; WP_011721160.1; NC_008593.1.
DR AlphaFoldDB; A0PXN8; -.
DR STRING; 386415.NT01CX_1056; -.
DR KEGG; cno:NT01CX_1056; -.
DR PATRIC; fig|386415.7.peg.165; -.
DR eggNOG; COG0480; Bacteria.
DR HOGENOM; CLU_002794_4_1_9; -.
DR Proteomes; UP000008220; Chromosome.
DR GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR GO; GO:0003746; F:translation elongation factor activity; IEA:UniProtKB-KW.
DR CDD; cd04170; EF-G_bact; 1.
DR CDD; cd16262; EFG_III; 1.
DR CDD; cd01434; EFG_mtEFG1_IV; 1.
DR CDD; cd03713; EFG_mtEFG_C; 1.
DR CDD; cd04088; EFG_mtEFG_II; 1.
DR Gene3D; 3.30.230.10; -; 1.
DR Gene3D; 3.30.70.240; -; 1.
DR Gene3D; 3.30.70.870; Elongation Factor G (Translational Gtpase), domain 3; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 2.40.30.10; Translation factors; 1.
DR InterPro; IPR041095; EFG_II.
DR InterPro; IPR009022; EFG_III.
DR InterPro; IPR035647; EFG_III/V.
DR InterPro; IPR047872; EFG_IV.
DR InterPro; IPR035649; EFG_V.
DR InterPro; IPR000640; EFG_V-like.
DR InterPro; IPR004161; EFTu-like_2.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR020568; Ribosomal_Su5_D2-typ_SF.
DR InterPro; IPR014721; Ribsml_uS5_D2-typ_fold_subgr.
DR InterPro; IPR005225; Small_GTP-bd_dom.
DR InterPro; IPR000795; T_Tr_GTP-bd_dom.
DR InterPro; IPR009000; Transl_B-barrel_sf.
DR InterPro; IPR004540; Transl_elong_EFG/EF2.
DR InterPro; IPR005517; Transl_elong_EFG/EF2_IV.
DR NCBIfam; TIGR00484; EF-G; 1.
DR NCBIfam; TIGR00231; small_GTP; 1.
DR PANTHER; PTHR43261:SF1; RIBOSOME-RELEASING FACTOR 2, MITOCHONDRIAL; 1.
DR PANTHER; PTHR43261; TRANSLATION ELONGATION FACTOR G-RELATED; 1.
DR Pfam; PF00679; EFG_C; 1.
DR Pfam; PF14492; EFG_III; 1.
DR Pfam; PF03764; EFG_IV; 1.
DR Pfam; PF00009; GTP_EFTU; 1.
DR Pfam; PF03144; GTP_EFTU_D2; 1.
DR PRINTS; PR00315; ELONGATNFCT.
DR SMART; SM00838; EFG_C; 1.
DR SMART; SM00889; EFG_IV; 1.
DR SUPFAM; SSF54980; EF-G C-terminal domain-like; 2.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF54211; Ribosomal protein S5 domain 2-like; 1.
DR SUPFAM; SSF50447; Translation proteins; 1.
DR PROSITE; PS51722; G_TR_2; 1.
PE 3: Inferred from homology;
KW Elongation factor {ECO:0000313|EMBL:ABK60531.1};
KW GTP-binding {ECO:0000256|ARBA:ARBA00023134};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Protein biosynthesis {ECO:0000313|EMBL:ABK60531.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000008220}.
FT DOMAIN 7..280
FT /note="Tr-type G"
FT /evidence="ECO:0000259|PROSITE:PS51722"
SQ SEQUENCE 692 AA; 77298 MW; B875BD0C30D2329F CRC64;
MKSYSTQNLR NIGFIGHSGS GKTTLTEAIL YCTKTIDRFG KIAEGNTISD YDPEEKKRKI
SIATSIIPCE WNNIKINILD TPGYFDFVGE MIEALRAVDT AIITLSGKSG VKVGTEKVWK
YVNKLNIPRA FFINKLDREN SNFEKVLDQL KDRFGMSVVP IQYPIGKEEE FKGVINLIDK
KARIFNPKNE QMEVSEIPTE LLPKVDEYRK MIIESVAETD EVLLEKYLND GELTNSELYN
GIISGARDGD IAPVLCGSAF KCIGINTFLE DIMECFPCPK ECREIQAINT GNNEPINIKM
DENKPFSAFV FKTVADPFVG KLSIFKVMTG KIKSDSVVYN VNKKKQEKFS NLYVVRGKDE
ISAKEIVAGD IGAVPKLQYT STGDTLSENK YAVMYEKIDF PEPVISMAIV PKSKGDEDKI
SSGLYKLTEE DPTFTISRDE ENADTIISGV GETHLDVIVN KLKNKFGVSI ELKDPKIPYR
ETIRKVSDVQ GKHKKQSGGH GQYGDVKIKF EPRCDGKTDL LFIDKIFGGV VPKQYIPAVE
KGLKESMKHG ALAGFPVIGL KATLHDGSYH SVDSSEMAFK IAASIAYKKA MQQGDSVLLE
PIMHLEVHVP NDYMGDVMAD INKKRGRVLG MDSCGDLEKI IAEVPLAEVL KYATDLRALT
GARGSFKMKF ERYEEVPYNE AEKIINKIKE DK
//
