ID A0QQS3_MYCS2 Unreviewed; 337 AA.
AC A0QQS3;
DT 09-JAN-2007, integrated into UniProtKB/TrEMBL.
DT 09-JAN-2007, sequence version 1.
DT 27-MAR-2024, entry version 114.
DE SubName: Full=Transcriptional regulator, TetR family protein {ECO:0000313|EMBL:ABK72767.1};
GN OrderedLocusNames=MSMEG_0859 {ECO:0000313|EMBL:ABK72767.1};
OS Mycolicibacterium smegmatis (strain ATCC 700084 / mc(2)155) (Mycobacterium
OS smegmatis).
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Mycobacteriaceae;
OC Mycolicibacterium.
OX NCBI_TaxID=246196 {ECO:0000313|EMBL:ABK72767.1, ECO:0000313|Proteomes:UP000000757};
RN [1] {ECO:0000313|EMBL:ABK72767.1, ECO:0000313|Proteomes:UP000000757}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 700084 / mc(2)155 {ECO:0000313|Proteomes:UP000000757};
RA Fleischmann R.D., Dodson R.J., Haft D.H., Merkel J.S., Nelson W.C.,
RA Fraser C.M.;
RL Submitted (OCT-2006) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; CP000480; ABK72767.1; -; Genomic_DNA.
DR RefSeq; YP_885261.1; NC_008596.1.
DR AlphaFoldDB; A0QQS3; -.
DR STRING; 246196.MSMEG_0859; -.
DR PaxDb; 246196-MSMEI_0838; -.
DR KEGG; msm:MSMEG_0859; -.
DR PATRIC; fig|246196.19.peg.849; -.
DR eggNOG; COG1309; Bacteria.
DR eggNOG; COG3832; Bacteria.
DR OrthoDB; 6624781at2; -.
DR Proteomes; UP000000757; Chromosome.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:UniProt.
DR CDD; cd07825; SRPBCC_7; 1.
DR Gene3D; 3.30.530.20; -; 1.
DR Gene3D; 1.10.357.10; Tetracycline Repressor, domain 2; 1.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR001647; HTH_TetR.
DR InterPro; IPR019587; Polyketide_cyclase/dehydratase.
DR InterPro; IPR023393; START-like_dom_sf.
DR PANTHER; PTHR30055; HTH-TYPE TRANSCRIPTIONAL REGULATOR RUTR; 1.
DR PANTHER; PTHR30055:SF164; TRANSCRIPTIONAL REPRESSOR MCE3R; 1.
DR Pfam; PF10604; Polyketide_cyc2; 1.
DR Pfam; PF00440; TetR_N; 1.
DR PRINTS; PR00455; HTHTETR.
DR SUPFAM; SSF55961; Bet v1-like; 1.
DR SUPFAM; SSF46689; Homeodomain-like; 1.
DR PROSITE; PS50977; HTH_TETR_2; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|PROSITE-ProRule:PRU00335};
KW Reference proteome {ECO:0000313|Proteomes:UP000000757};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 6..66
FT /note="HTH tetR-type"
FT /evidence="ECO:0000259|PROSITE:PS50977"
FT DNA_BIND 29..48
FT /note="H-T-H motif"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00335"
SQ SEQUENCE 337 AA; 37055 MW; F41FC7918BF80754 CRC64;
MAPPRKHETD AILDAARALV LTEGPRAAGV AAIAKASGAP VGTLYHRFGN RDGILKATWL
RGIERFQRRA MAADGATPVD VAVAMAGAVL QFARDEPEDA RLLLSIRRAD LLDGGPDADF
DATLADMNAP VFERLHELAR GIFGRDDDRA MDAVMRAVAD LPYATVRRHI DDGKWPVWLS
EDLATSVRRL LSVDKIVSAS REIAAPSDVI FELIADPAQQ PRWDGNENLL RMASGGRVRG
VGEVFTMEIK QGGFRDNHVI EFEEGRRIAW RPAVAGEQPL GHLWRWELQP AGEGRTLVTH
TYDWTQLTDE KRFPKASATT ADKLQESVDR LAAIVEG
//
