ID A0R2H4_MYCS2 Unreviewed; 468 AA.
AC A0R2H4;
DT 09-JAN-2007, integrated into UniProtKB/TrEMBL.
DT 09-JAN-2007, sequence version 1.
DT 27-MAR-2024, entry version 107.
DE SubName: Full=Acyl-CoA synthase {ECO:0000313|EMBL:ABK70979.1};
GN OrderedLocusNames=MSMEG_5114 {ECO:0000313|EMBL:ABK70979.1};
OS Mycolicibacterium smegmatis (strain ATCC 700084 / mc(2)155) (Mycobacterium
OS smegmatis).
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Mycobacteriaceae;
OC Mycolicibacterium.
OX NCBI_TaxID=246196 {ECO:0000313|EMBL:ABK70979.1, ECO:0000313|Proteomes:UP000000757};
RN [1] {ECO:0000313|EMBL:ABK70979.1, ECO:0000313|Proteomes:UP000000757}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 700084 / mc(2)155 {ECO:0000313|Proteomes:UP000000757};
RA Fleischmann R.D., Dodson R.J., Haft D.H., Merkel J.S., Nelson W.C.,
RA Fraser C.M.;
RL Submitted (OCT-2006) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; CP000480; ABK70979.1; -; Genomic_DNA.
DR RefSeq; WP_011730326.1; NZ_SIJM01000038.1.
DR RefSeq; YP_889362.1; NC_008596.1.
DR AlphaFoldDB; A0R2H4; -.
DR STRING; 246196.MSMEG_5114; -.
DR PaxDb; 246196-MSMEI_4986; -.
DR GeneID; 66736431; -.
DR KEGG; msm:MSMEG_5114; -.
DR PATRIC; fig|246196.19.peg.4989; -.
DR eggNOG; COG0318; Bacteria.
DR OrthoDB; 5168424at2; -.
DR Proteomes; UP000000757; Chromosome.
DR CDD; cd05941; MCS; 1.
DR Gene3D; 3.30.300.30; -; 1.
DR Gene3D; 3.40.50.12780; N-terminal domain of ligase-like; 1.
DR InterPro; IPR025110; AMP-bd_C.
DR InterPro; IPR045851; AMP-bd_C_sf.
DR InterPro; IPR020845; AMP-binding_CS.
DR InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR InterPro; IPR042099; ANL_N_sf.
DR PANTHER; PTHR43201; ACYL-COA SYNTHETASE; 1.
DR PANTHER; PTHR43201:SF8; FATTY ACID COA SYNTHETASE FAMILY; 1.
DR Pfam; PF00501; AMP-binding; 1.
DR Pfam; PF13193; AMP-binding_C; 1.
DR SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 1.
DR PROSITE; PS00455; AMP_BINDING; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000000757}.
FT DOMAIN 45..335
FT /note="AMP-dependent synthetase/ligase"
FT /evidence="ECO:0000259|Pfam:PF00501"
FT DOMAIN 387..458
FT /note="AMP-binding enzyme C-terminal"
FT /evidence="ECO:0000259|Pfam:PF13193"
SQ SEQUENCE 468 AA; 49773 MW; 2151F78DF784877B CRC64;
MLLASLNPAA VAAGADIADA VRIDGAVLSR SDLVGGATSV AERVAVAQRV AVLAKPTATT
VLAITGCLIA GVTVVPVPAD VGVAERRHML EDSGAQAWLG ERPDDAEGLP HIPVRLHARS
WHRYAEPPPE STAIIMYTSG TTGLPKGVPI TRNAIAADID GLAKAWEWTP EDTLVHGLPL
FHVHGLVLGL IGSLRIGNRF VHTGKPTPER YAEAKGTLYF GVPTVWSRVV NNLDAALALS
SARLLVSGSA PLPVPVFEQL TKLTGQPPVE RYGSTESLIT ITTLVNGERR PGWVGVPIEG
VRTRLVDENG AEVPHDGETI GRLQIKGPTV FEGYLNRPEA TAEAFDDDGW FRTGDVAVID
AGGMHRIVGR ESVDLIKSGG YRIGAGEIET VLLGHPGVKE AAVVGVPDDD LGQRIVAYVV
GDAESDTLID FVAKQLSVHK RPREVRIVDS LPRNAMGKVL KKELAQWR
//
