ID   A0RN05_CAMFF            Unreviewed;       921 AA.
AC   A0RN05;
DT   09-JAN-2007, integrated into UniProtKB/TrEMBL.
DT   09-JAN-2007, sequence version 1.
DT   27-MAR-2024, entry version 103.
DE   RecName: Full=DNA 3'-5' helicase {ECO:0000256|ARBA:ARBA00034808};
DE            EC=5.6.2.4 {ECO:0000256|ARBA:ARBA00034808};
GN   OrderedLocusNames=CFF8240_0386 {ECO:0000313|EMBL:ABK82420.1};
OS   Campylobacter fetus subsp. fetus (strain 82-40).
OC   Bacteria; Campylobacterota; Epsilonproteobacteria; Campylobacterales;
OC   Campylobacteraceae; Campylobacter.
OX   NCBI_TaxID=360106 {ECO:0000313|EMBL:ABK82420.1, ECO:0000313|Proteomes:UP000000760};
RN   [1] {ECO:0000313|Proteomes:UP000000760}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=82-40 {ECO:0000313|Proteomes:UP000000760};
RA   Fouts D.E., Nelson K.E.;
RT   "Sequence of Campylobacter fetus subsp. fetus 82-40.";
RL   Submitted (NOV-2006) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC         ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC         ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=5.6.2.4;
CC         Evidence={ECO:0000256|ARBA:ARBA00034618};
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; CP000487; ABK82420.1; -; Genomic_DNA.
DR   RefSeq; WP_011731795.1; NC_008599.1.
DR   AlphaFoldDB; A0RN05; -.
DR   GeneID; 61064230; -.
DR   KEGG; cff:CFF8240_0386; -.
DR   PATRIC; fig|360106.6.peg.381; -.
DR   eggNOG; COG1074; Bacteria.
DR   HOGENOM; CLU_010638_1_0_7; -.
DR   Proteomes; UP000000760; Chromosome.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0016887; F:ATP hydrolysis activity; IEA:RHEA.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0003678; F:DNA helicase activity; IEA:InterPro.
DR   Gene3D; 3.90.320.10; -; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 4.
DR   InterPro; IPR014017; DNA_helicase_UvrD-like_C.
DR   InterPro; IPR000212; DNA_helicase_UvrD/REP.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR011604; PDDEXK-like_dom_sf.
DR   InterPro; IPR014016; UvrD-like_ATP-bd.
DR   PANTHER; PTHR11070:SF64; ATP-DEPENDENT DNA HELICASE REP; 1.
DR   PANTHER; PTHR11070; UVRD / RECB / PCRA DNA HELICASE FAMILY MEMBER; 1.
DR   Pfam; PF00580; UvrD-helicase; 1.
DR   Pfam; PF13361; UvrD_C; 2.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   PROSITE; PS51198; UVRD_HELICASE_ATP_BIND; 1.
PE   4: Predicted;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW   ProRule:PRU00560}; DNA damage {ECO:0000256|ARBA:ARBA00022763};
KW   DNA repair {ECO:0000256|ARBA:ARBA00023204};
KW   Exonuclease {ECO:0000256|ARBA:ARBA00022839};
KW   Helicase {ECO:0000256|ARBA:ARBA00022806, ECO:0000256|PROSITE-
KW   ProRule:PRU00560};
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|PROSITE-
KW   ProRule:PRU00560}; Nuclease {ECO:0000256|ARBA:ARBA00022722};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW   ProRule:PRU00560}; Reference proteome {ECO:0000313|Proteomes:UP000000760}.
FT   DOMAIN          1..409
FT                   /note="UvrD-like helicase ATP-binding"
FT                   /evidence="ECO:0000259|PROSITE:PS51198"
FT   BINDING         11..18
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00560"
SQ   SEQUENCE   921 AA;  106287 MW;  D53D25C4FF8DB7B0 CRC64;
     MSFSRYLALE ASAGSGKTFA LSVRFIALIL QGNDIAKILA LTFTKKAANE MKSRIIDAFC
     NLHESSKKNE LNELEKILEL SAVDILSLRD KYMGNFLKNE LKISTFDSFF TMILRQFSLN
     LGIMPDFKAG TSLNGLTRSE FIKNLKQNHL LESFAFYIKE TNSNKNRVFE TLELLYENIS
     LPSFGENSKI PDESYVFAKF SELKSLALEI SSDKNFLKNF EANTVSQIAG KPLIKEFDSK
     KYFEKAALNA KFMMIRDELI SNLKKYYLEY EQFKINELLK FIYLYKYSRF EAIKKENALD
     FIDVTRLVYE LLGNIDSDML YFRLDDRIKH ILIDEFQDTN IIQYDILLPL IEETLSGSGQ
     NDIGSFFYVG DIKQSIYRFR GGRKELFSRL RNSYKQIETL SLESNYRSAK NIVNFVNQTF
     SNKIKYYKTQ LSCLENEGYV EVCEFVSDEF YDTLFQKIEF FVKNGVRYDD IAILCWKNSD
     IINIKDKLEK SGVPVATGGS NLLINSANVR VVLDFIKYCL FGDEIYIYSV HEFIGEKKSK
     LSLNATAELA STLKFVASYL NLECFDKNLL KLYEISLGYA DIFDFIFNIQ NDQTPSADTS
     HCGITLLTVH KSKGLEFDHV IVADRLSRAG SNIDVFITEY NNSEQKWDIK LNDSALQNLG
     DSEFINLKQK CKDLDYEEDI NKLYVALTRA KNSLIVMSKL DSNGLKPSYF KAFTSSKEQI
     CYLDLKPFSV GKIEPSKTSM SFYGGLERLE EFETIKKQAV SDKQNDEYEL NLESIYFGEA
     LHYCLEMIFD FEEENLKNAK TALINQFGAI LSKNSIEDII NRVLNLINSV EFKNIIKDKN
     ILKEQDIAFN QVIKRLDLLC IGDDEIVVMD YKSSKKFITQ NEDQVREYMS ILSQIYPQKR
     VVGKIIYLLN DKVEFLNVDL I
//