ID A0YBI5_9GAMM Unreviewed; 837 AA.
AC A0YBI5;
DT 23-JAN-2007, integrated into UniProtKB/TrEMBL.
DT 23-JAN-2007, sequence version 1.
DT 27-MAR-2024, entry version 62.
DE RecName: Full=Dimethylglycine dehydrogenase {ECO:0008006|Google:ProtNLM};
GN ORFNames=GP2143_05675 {ECO:0000313|EMBL:EAW31915.1};
OS marine gamma proteobacterium HTCC2143.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Cellvibrionales;
OC Spongiibacteraceae; BD1-7 clade.
OX NCBI_TaxID=247633 {ECO:0000313|EMBL:EAW31915.1, ECO:0000313|Proteomes:UP000004931};
RN [1] {ECO:0000313|EMBL:EAW31915.1, ECO:0000313|Proteomes:UP000004931}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=HTCC2143 {ECO:0000313|EMBL:EAW31915.1,
RC ECO:0000313|Proteomes:UP000004931};
RX PubMed=20601481; DOI=10.1128/JB.00683-10;
RA Oh H.M., Kang I., Ferriera S., Giovannoni S.J., Cho J.C.;
RT "Genome sequence of the oligotrophic marine Gammaproteobacterium HTCC2143,
RT isolated from the Oregon Coast.";
RL J. Bacteriol. 192:4530-4531(2010).
CC -!- SIMILARITY: Belongs to the GcvT family.
CC {ECO:0000256|ARBA:ARBA00008609}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EAW31915.1}.
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DR EMBL; AAVT01000002; EAW31915.1; -; Genomic_DNA.
DR AlphaFoldDB; A0YBI5; -.
DR STRING; 247633.GP2143_05675; -.
DR eggNOG; COG0404; Bacteria.
DR eggNOG; COG0665; Bacteria.
DR OrthoDB; 5287468at2; -.
DR Proteomes; UP000004931; Unassembled WGS sequence.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR Gene3D; 2.40.30.110; Aminomethyltransferase beta-barrel domains; 1.
DR Gene3D; 3.30.70.1400; Aminomethyltransferase beta-barrel domains; 1.
DR Gene3D; 3.30.9.10; D-Amino Acid Oxidase, subunit A, domain 2; 1.
DR Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 1.
DR InterPro; IPR006076; FAD-dep_OxRdtase.
DR InterPro; IPR036188; FAD/NAD-bd_sf.
DR InterPro; IPR032503; FAO_M.
DR InterPro; IPR028896; GCST/YgfZ/DmdA.
DR InterPro; IPR013977; GCV_T_C.
DR InterPro; IPR006222; GCV_T_N.
DR InterPro; IPR029043; GcvT/YgfZ_C.
DR InterPro; IPR027266; TrmE/GcvT_dom1.
DR PANTHER; PTHR43757; AMINOMETHYLTRANSFERASE; 1.
DR PANTHER; PTHR43757:SF2; AMINOMETHYLTRANSFERASE, MITOCHONDRIAL; 1.
DR Pfam; PF01266; DAO; 1.
DR Pfam; PF16350; FAO_M; 1.
DR Pfam; PF01571; GCV_T; 1.
DR Pfam; PF08669; GCV_T_C; 1.
DR SUPFAM; SSF101790; Aminomethyltransferase beta-barrel domain; 1.
DR SUPFAM; SSF54373; FAD-linked reductases, C-terminal domain; 1.
DR SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
DR SUPFAM; SSF103025; Folate-binding domain; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000004931}.
FT DOMAIN 6..368
FT /note="FAD dependent oxidoreductase"
FT /evidence="ECO:0000259|Pfam:PF01266"
FT DOMAIN 371..425
FT /note="FAD dependent oxidoreductase central"
FT /evidence="ECO:0000259|Pfam:PF16350"
FT DOMAIN 427..723
FT /note="Aminomethyltransferase folate-binding"
FT /evidence="ECO:0000259|Pfam:PF01571"
FT DOMAIN 750..829
FT /note="Glycine cleavage T-protein C-terminal barrel"
FT /evidence="ECO:0000259|Pfam:PF08669"
SQ SEQUENCE 837 AA; 92747 MW; EC4F99BCDB3717C7 CRC64;
MKSSARVVVI GGGVVGVSTL YHLAKKGWTD VVLVERKELT SGSTWHAAGL LPLFNMSYSV
GKLHQYSVNF YHELEKETGQ DVGFKVVSNI RLATCEHRMD EYRYYAGVAQ TVGVDVRFLT
PEQVKDIWPM CNTEGLIGAI QHPDDGYIQP ADLTQALAKG ARSRGATIYR NTAVTAIEQQ
PDDSWIVKTD QGDISCEHVV SCTGNFARKT GEMVGLDIPV IPVEHQYLVT EAHPDILARK
EQGLPEQGVL RESDAGYYLR EEAGGMILGP YEKGAPCCYV DGPSDESEYE LFNQDLDRLM
PHIEACINRV PAFGEVGIKT VYNGAIAYAP DGNPIVGPAW QLKNFWLNEG HSFGITAAGG
AGWQLAEWII DGDPTVDMMG VDPRRFGPYA SRGYLRAKNE ESYANVFTTH FPDEERAAAR
PLKQSPCYDR MKALGAVFGH VYGWERPNWF APADYQLSAA DLDIADCLLN DNHSPAQEDG
RIVEKNSFRR SNYFDFVGQE CRHVQSNVGL LDMSAFSKFS VKGAGAGEWL NSLVANNIPK
GNGRVGLCHM LSKNGGVRAE FTIYKKGKDD YYLVSAGAME RHDGDYLFKN LPKDGSVQLQ
TITTQRGVFV IAGPRSRELL QKLTDTDLSN DNFKWLTGQF INVGFAQADA LRVNFVGELG
WELHHPIEMQ NYIFDEVMKA GAEFGIKPFG IRAMDAMRLE KSYRLIPREM SIEYSALESG
LDRFVQLDKA CDFIGKQALL DWKNRGFDNQ FVTLEVHGIK DADARGSEAI YKDGSIVGRA
TSGGYGFRIG KSLALGMIHP NLADVGTTME IEILGKRYQA TVIEESPYDP KNVALRS
//
