ID A1A1F6_BIFAA Unreviewed; 1036 AA.
AC A1A1F6;
DT 23-JAN-2007, integrated into UniProtKB/TrEMBL.
DT 23-JAN-2007, sequence version 1.
DT 27-MAR-2024, entry version 106.
DE SubName: Full=Glutamate-ammonia-ligase adenylyltransferase {ECO:0000313|EMBL:BAF39539.1};
GN Name=glnE {ECO:0000313|EMBL:BAF39539.1};
GN OrderedLocusNames=BAD_0758 {ECO:0000313|EMBL:BAF39539.1};
OS Bifidobacterium adolescentis (strain ATCC 15703 / DSM 20083 / NCTC 11814 /
OS E194a).
OC Bacteria; Actinomycetota; Actinomycetes; Bifidobacteriales;
OC Bifidobacteriaceae; Bifidobacterium.
OX NCBI_TaxID=367928 {ECO:0000313|EMBL:BAF39539.1, ECO:0000313|Proteomes:UP000008702};
RN [1] {ECO:0000313|EMBL:BAF39539.1, ECO:0000313|Proteomes:UP000008702}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 15703 / DSM 20083 / NCTC 11814 / E194a
RC {ECO:0000313|Proteomes:UP000008702};
RA Suzuki T., Tsuda Y., Kanou N., Inoue T., Kumazaki K., Nagano S., Hirai S.,
RA Tanaka K., Watanabe K.;
RT "Bifidobacterium adolescentis complete genome sequence.";
RL Submitted (DEC-2006) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; AP009256; BAF39539.1; -; Genomic_DNA.
DR AlphaFoldDB; A1A1F6; -.
DR STRING; 367928.BAD_0758; -.
DR PaxDb; 1680-BADO_0806; -.
DR KEGG; bad:BAD_0758; -.
DR HOGENOM; CLU_006233_1_0_11; -.
DR Proteomes; UP000008702; Chromosome.
DR GO; GO:0008882; F:[glutamate-ammonia-ligase] adenylyltransferase activity; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR CDD; cd05401; NT_GlnE_GlnD_like; 2.
DR Gene3D; 3.30.460.10; Beta Polymerase, domain 2; 2.
DR Gene3D; 1.20.120.330; Nucleotidyltransferases domain 2; 2.
DR InterPro; IPR023057; GlnE.
DR InterPro; IPR005190; GlnE_rpt_dom.
DR InterPro; IPR043519; NT_sf.
DR InterPro; IPR013546; PII_UdlTrfase/GS_AdlTrfase.
DR PANTHER; PTHR30621:SF0; BIFUNCTIONAL GLUTAMINE SYNTHETASE ADENYLYLTRANSFERASE_ADENYLYL-REMOVING ENZYME; 1.
DR PANTHER; PTHR30621; GLUTAMINE SYNTHETASE ADENYLYLTRANSFERASE; 1.
DR Pfam; PF08335; GlnD_UR_UTase; 2.
DR Pfam; PF03710; GlnE; 2.
DR SUPFAM; SSF81301; Nucleotidyltransferase; 2.
DR SUPFAM; SSF81593; Nucleotidyltransferase substrate binding subunit/domain; 2.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Magnesium {ECO:0000256|ARBA:ARBA00022842};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Nucleotidyltransferase {ECO:0000256|ARBA:ARBA00022695,
KW ECO:0000313|EMBL:BAF39539.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000008702};
KW Transferase {ECO:0000256|ARBA:ARBA00022695, ECO:0000313|EMBL:BAF39539.1}.
FT DOMAIN 90..338
FT /note="Glutamate-ammonia ligase adenylyltransferase
FT repeated"
FT /evidence="ECO:0000259|Pfam:PF03710"
FT DOMAIN 364..460
FT /note="PII-uridylyltransferase/Glutamine-synthetase
FT adenylyltransferase"
FT /evidence="ECO:0000259|Pfam:PF08335"
FT DOMAIN 625..864
FT /note="Glutamate-ammonia ligase adenylyltransferase
FT repeated"
FT /evidence="ECO:0000259|Pfam:PF03710"
FT DOMAIN 889..1032
FT /note="PII-uridylyltransferase/Glutamine-synthetase
FT adenylyltransferase"
FT /evidence="ECO:0000259|Pfam:PF08335"
SQ SEQUENCE 1036 AA; 116409 MW; 4C8A850DDD79A273 CRC64;
MGTMASSTHQ FEVLDLIRAG LQDLDTARTL LDELRADGID DDRLCLLMKT LEQTCEPDIA
LRNLVDIIKA LQSQGRDFHQ VITDDAGLVR LVTVLGVSDG MGKLMRFRPE LVMAAASDSC
ESHLYNHAQR RAHVLEAVGA DPADNRMPKA TKPLAEAATA LRQTYRKQLA AIMAQDATAD
DPIEIQPRIS QELSDLADAA LEGALAIARN EVDSSEHVRF AIIGMGKLGA RELNYVSDVD
LIYVVEPADA DTNGMTLNRV GTKMATTLQR VCQSVIMGVA EPTLWQIDGG LRPEGKDGPL
VRKLESHEAY YEQWAENWEF QALLKARPVA GDPDLGQAYM DMTRPFVWTA SKRDNFVYDC
QQMRKRVEDL IPAPLKDREI KLGRGGLRDV EFTVQMLQLV HGRADETLRT SSTLESLQRL
AEGGYVSRRQ AKKLSWDYRF ERVMEHRQQM WALKRTHLFP DLGKASLGGI ERKRDANDDE
LNHNLELRRL ARAFHMHPEE LVDKYDETRR EVRHLHMDIY YRPMLPINAG LDDEQVELSA
NAMQERFASI GFADPDAAMR HVTALTAGIS RAAKINRILL PAVLQWLGEG QNPDMGLLNW
RKLEEHFGTD SEYLGFLRDS PSAAQRLCHV LSNSRFLGDA LNKSVESVTW LGSDNDLQPR
SRESLDVQTH ASLERNVGSI NDFANSIRAM RRHEIERIGL GWMSGVIDDK ASLAGMTDVY
DTAIDASLTW AIRHQTQEMG FDEAPAAIAV IGMGRYGGRE VNFSSDADVI IIYRPSDNAD
DNQANLFARK VQEDLRAILQ GPTTLEPKIE LDMDLRPEGK NGPLVRSYAS CEEYYRSWAS
TWEHQALLRA RYAAGDAALA EDFLMNVADP LRYPKIDLTE AQVAEIRKLK ARMEAERLPR
GVRRDRHLKL GKGGLSDVEW TIQLLQLQHA GDNANLRVNG TMQALDELER RKLVSAGDAV
VLRRAWWMCT AARNGSYLWS GRVNQADILP DDTYSLGGLA VYLGYDANRG QHFENDLLAV
MRKARDVTER LFYGLS
//
