ID A1C3U8_ASPCL Unreviewed; 510 AA.
AC A1C3U8;
DT 23-JAN-2007, integrated into UniProtKB/TrEMBL.
DT 23-JAN-2007, sequence version 1.
DT 27-MAR-2024, entry version 63.
DE SubName: Full=DUF895 domain protein {ECO:0000313|EMBL:EAW15088.1};
GN ORFNames=ACLA_057440 {ECO:0000313|EMBL:EAW15088.1};
OS Aspergillus clavatus (strain ATCC 1007 / CBS 513.65 / DSM 816 / NCTC 3887 /
OS NRRL 1 / QM 1276 / 107).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus;
OC Aspergillus subgen. Fumigati.
OX NCBI_TaxID=344612 {ECO:0000313|EMBL:EAW15088.1, ECO:0000313|Proteomes:UP000006701};
RN [1] {ECO:0000313|EMBL:EAW15088.1, ECO:0000313|Proteomes:UP000006701}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 1007 / CBS 513.65 / DSM 816 / NCTC 3887 / NRRL 1
RC {ECO:0000313|Proteomes:UP000006701};
RX PubMed=18404212; DOI=10.1371/journal.pgen.1000046;
RA Fedorova N.D., Khaldi N., Joardar V.S., Maiti R., Amedeo P., Anderson M.J.,
RA Crabtree J., Silva J.C., Badger J.H., Albarraq A., Angiuoli S., Bussey H.,
RA Bowyer P., Cotty P.J., Dyer P.S., Egan A., Galens K., Fraser-Liggett C.M.,
RA Haas B.J., Inman J.M., Kent R., Lemieux S., Malavazi I., Orvis J.,
RA Roemer T., Ronning C.M., Sundaram J.P., Sutton G., Turner G., Venter J.C.,
RA White O.R., Whitty B.R., Youngman P., Wolfe K.H., Goldman G.H.,
RA Wortman J.R., Jiang B., Denning D.W., Nierman W.C.;
RT "Genomic islands in the pathogenic filamentous fungus Aspergillus
RT fumigatus.";
RL PLoS Genet. 4:E1000046-E1000046(2008).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; DS026990; EAW15088.1; -; Genomic_DNA.
DR RefSeq; XP_001276514.1; XM_001276513.1.
DR AlphaFoldDB; A1C3U8; -.
DR EnsemblFungi; EAW15088; EAW15088; ACLA_057440.
DR GeneID; 4708910; -.
DR KEGG; act:ACLA_057440; -.
DR VEuPathDB; FungiDB:ACLA_057440; -.
DR eggNOG; KOG3098; Eukaryota.
DR HOGENOM; CLU_030884_1_2_1; -.
DR OMA; AYWFMGA; -.
DR OrthoDB; 662261at2759; -.
DR Proteomes; UP000006701; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR CDD; cd06178; MFS_unc93-like; 1.
DR Gene3D; 1.20.1250.20; MFS general substrate transporter like domains; 1.
DR InterPro; IPR011701; MFS.
DR InterPro; IPR036259; MFS_trans_sf.
DR PANTHER; PTHR23294:SF54; DUF895 DOMAIN MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_8G04110); 1.
DR PANTHER; PTHR23294; ET TRANSLATION PRODUCT-RELATED; 1.
DR Pfam; PF07690; MFS_1; 1.
DR SUPFAM; SSF103473; MFS general substrate transporter; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000006701};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 56..75
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 95..111
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 118..137
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 143..168
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 180..202
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 214..233
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 270..288
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 308..326
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 338..357
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 377..400
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 443..464
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REGION 1..26
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 488..510
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..22
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 510 AA; 56660 MW; 0302B4DA7D696CEE CRC64;
MASEKPEDIH RTEKEAPEIT SDPEAGHDNA IVGKPWMYKS LQIGPWKLPY FASPEFQLVL
VSFVCFLCPG MFNAVSGLGG GGQVKQTDVS NANTALYSTF AVVGFFAGSI ANRIGLQLTI
SFGGFGYFLY VAALLSYNHN ENAGFLIFAG ALLGVCAGLL WCAQGAVMMS YPLEHEKGKF
IAIFWVIFNL GGVIGSLIPL GQNLHSTVGK VNDGTYIAFM VLMAAGFILA WSLSDSKYIV
RKNGTRVIVM KNPTWKSEFL GLYETLRSDY YIVLFFPMFL ASNWFYGYHF NSVNGAYFNI
RTRSLNSLLY WLSQMIGAFV FGHTLDLKFF SRSMRAKLNW ALLLIITMAT WGGGYAFQKG
YTRETAKQDV DWTTSGYVGP MFLYMFYGFY DAAFQTCAYW FMGSLTNNGR KLANFAGFYK
GIQSAGAAGM WRLDAENTPF MTEFASCWGL LVGSLLIAAP IIFFKVKDHI DMEEDLKFSD
ETAQDVKGIP IEDRASSSKE DLSEKRASVA
//
